Ensembl ID
ENSG00000099381
Gene ID
9739
Accession
29010
Gene Symbol
SETD1A
Alias
Set1;EPEDD;EPEO2;KMT2F;Set1A;NEDSID
Full Name
SET domain containing 1A, histone lysine methyltransferase
Position
16 : 30957754 - 30984664
Length
26911 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily. [provided by RefSeq, Dec 2016]
ENSG00000099381 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000099381
SETD1A
0.33
1.32e-11
KIRC
ENSG00000099381
SETD1A
0.27
3.86e-12
BRCA
ENSG00000099381
SETD1A
0.49
1.85e-13
KIRP
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000099381
SETD1A
tumour
20725831
ENSG00000099381
SETD1A
cancers
22989411
ENSG00000099381
SETD1A
cancer
22990868
ENSG00000099381
SETD1A
cancer
23235145
ENSG00000099381
SETD1A
cancers
24900672
ENSG00000099381
SETD1A
colon cancer
24948597
ENSG00000099381
SETD1A
breast cancers
25373480
ENSG00000099381
SETD1A
breast cancer
25537518
ENSG00000099381
SETD1A
liver tumors
25658102
ENSG00000099381
SETD1A
cancers
26147337
ENSG00000099381
SETD1A
tumours
26394836
ENSG00000099381
SETD1A
Liver Cancer
26581161
ENSG00000099381
SETD1A
prostate cancer
27268279
ENSG00000099381
SETD1A
cancers
27563068
ENSG00000099381
SETD1A
ovarian cancer
28385531
ENSG00000099381
SETD1A
tumours
28587163
ENSG00000099381
SETD1A
Tumor
28828481
ENSG00000099381
SETD1A
cancer
29177029
ENSG00000099381
SETD1A
cancers
29474905
ENSG00000099381
SETD1A
cancer
30008910
ENSG00000099381
SETD1A
breast cancer
30191958
ENSG00000099381
SETD1A
cancer
30221689
ENSG00000099381
SETD1A
cancers
30448059
ENSG00000099381
SETD1A
breast cancers
30583339
ENSG00000099381
SETD1A
breast tumors
30990809
ENSG00000099381
SETD1A
tumors
31005631
ENSG00000099381
SETD1A
tumor
31253781
ENSG00000099381
SETD1A
triple negative breast cancer
31552595
ENSG00000099381
SETD1A
cancer
31846841
ENSG00000099381
SETD1A
breast cancers
31897900
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000099381
SETD1A
STAD
0.029
low
show
ENSG00000099381
SETD1A
UVM
0.0096
low
show
ENSG00000099381
SETD1A
PAAD
0.024
low
show
ENSG00000099381
SETD1A
THCA
6e-04
high
show
ENSG00000099381
SETD1A
LUSC
0.028
low
show
ENSG00000099381
SETD1A
HNSC
0.013
low
show
ENSG00000099381
SETD1A
KICH
0.0041
low
show
ENSG00000099381
SETD1A
PCPG
0.0089
low
show
ENSG00000099381
SETD1A
THYM
0.0038
low
show
ENSG00000099381
SETD1A
BRCA
0.037
high
show
ENSG00000099381
SETD1A
KIRC
0.003
high
show
ENSG00000099381
SETD1A
LAML
0.013
high
show
ENSG00000099381
SETD1A
SKCM
0.044
high
show
ENSG00000099381
SETD1A
CESC
0.04
low
show
ENSG00000099381
SETD1A
LIHC
0.0011
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000099381
SETD1A
COAD
Amp
0.909240
0.071917
0.456949
0.277162
ENSG00000099381
SETD1A
UCS
Amp
1.474218
0.617969
0.824056
0.357143
ENSG00000099381
SETD1A
UCEC
Amp
2.593149
0.144084
0.705903
0.122449
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