Ensembl ID ENSG00000099381 Gene ID 9739 Accession 29010
Gene Symbol SETD1A Alias Set1;EPEDD;EPEO2;KMT2F;Set1A;NEDSID Full Name SET domain containing 1A, histone lysine methyltransferase
Position 16 : 30957754 - 30984664 Length 26911 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily. [provided by RefSeq, Dec 2016]

ENSG00000099381 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000099381 SETD1A 0.33 1.32e-11 KIRC
ENSG00000099381 SETD1A 0.27 3.86e-12 BRCA
ENSG00000099381 SETD1A 0.49 1.85e-13 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000099381 SETD1A tumour 20725831
ENSG00000099381 SETD1A cancers 22989411
ENSG00000099381 SETD1A cancer 22990868
ENSG00000099381 SETD1A cancer 23235145
ENSG00000099381 SETD1A cancers 24900672
ENSG00000099381 SETD1A colon cancer 24948597
ENSG00000099381 SETD1A breast cancers 25373480
ENSG00000099381 SETD1A breast cancer 25537518
ENSG00000099381 SETD1A liver tumors 25658102
ENSG00000099381 SETD1A cancers 26147337
ENSG00000099381 SETD1A tumours 26394836
ENSG00000099381 SETD1A Liver Cancer 26581161
ENSG00000099381 SETD1A prostate cancer 27268279
ENSG00000099381 SETD1A cancers 27563068
ENSG00000099381 SETD1A ovarian cancer 28385531
ENSG00000099381 SETD1A tumours 28587163
ENSG00000099381 SETD1A Tumor 28828481
ENSG00000099381 SETD1A cancer 29177029
ENSG00000099381 SETD1A cancers 29474905
ENSG00000099381 SETD1A cancer 30008910
ENSG00000099381 SETD1A breast cancer 30191958
ENSG00000099381 SETD1A cancer 30221689
ENSG00000099381 SETD1A cancers 30448059
ENSG00000099381 SETD1A breast cancers 30583339
ENSG00000099381 SETD1A breast tumors 30990809
ENSG00000099381 SETD1A tumors 31005631
ENSG00000099381 SETD1A tumor 31253781
ENSG00000099381 SETD1A triple negative breast cancer 31552595
ENSG00000099381 SETD1A cancer 31846841
ENSG00000099381 SETD1A breast cancers 31897900
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000099381 SETD1A STAD 0.029 low
ENSG00000099381 SETD1A UVM 0.0096 low
ENSG00000099381 SETD1A PAAD 0.024 low
ENSG00000099381 SETD1A THCA 6e-04 high
ENSG00000099381 SETD1A LUSC 0.028 low
ENSG00000099381 SETD1A HNSC 0.013 low
ENSG00000099381 SETD1A KICH 0.0041 low
ENSG00000099381 SETD1A PCPG 0.0089 low
ENSG00000099381 SETD1A THYM 0.0038 low
ENSG00000099381 SETD1A BRCA 0.037 high
ENSG00000099381 SETD1A KIRC 0.003 high
ENSG00000099381 SETD1A LAML 0.013 high
ENSG00000099381 SETD1A SKCM 0.044 high
ENSG00000099381 SETD1A CESC 0.04 low
ENSG00000099381 SETD1A LIHC 0.0011 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000099381 SETD1A COAD Amp 0.909240 0.071917 0.456949 0.277162
ENSG00000099381 SETD1A UCS Amp 1.474218 0.617969 0.824056 0.357143
ENSG00000099381 SETD1A UCEC Amp 2.593149 0.144084 0.705903 0.122449