Ensembl ID ENSG00000096696 Gene ID 1832 Accession 3052
Gene Symbol DSP Alias DP;DCWHKTA Full Name desmoplakin
Position 6 : 7541617 - 7586714 Length 45098 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

ENSG00000096696 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000096696 DSP -1.4 1.04e-18 KIRC
ENSG00000096696 DSP 3.89 3.62e-152 LUSC
ENSG00000096696 DSP -1.4 3.25e-11 STAD
ENSG00000096696 DSP 2.06 4.22e-41 UCEC
ENSG00000096696 DSP 5.34 4.19e-16 CESC
ENSG00000096696 DSP 2.17 2.04e-34 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000096696 DSP tumour 10095451
ENSG00000096696 DSP tumour 10320997
ENSG00000096696 DSP breast cancer 10533469
ENSG00000096696 DSP tumor 11408923
ENSG00000096696 DSP tumours 11508766
ENSG00000096696 DSP tumor 11850808
ENSG00000096696 DSP cancer 12718697
ENSG00000096696 DSP meningeal tumors 12845453
ENSG00000096696 DSP tumors 1377859
ENSG00000096696 DSP breast cancer 15084247
ENSG00000096696 DSP tumor 15190119
ENSG00000096696 DSP tumors 15609307
ENSG00000096696 DSP tumor 16280302
ENSG00000096696 DSP tumour 16489176
ENSG00000096696 DSP tumour 16603084
ENSG00000096696 DSP cancer 17194181
ENSG00000096696 DSP testicular non-seminomatous germ cell tumors 1725164
ENSG00000096696 DSP tumour 17606330
ENSG00000096696 DSP breast cancers 18179684
ENSG00000096696 DSP tumor 18298792
ENSG00000096696 DSP cancer 18855677
ENSG00000096696 DSP oropharyngeal cancer 19386346
ENSG00000096696 DSP tumors 20413845
ENSG00000096696 DSP tumor 20862307
ENSG00000096696 DSP tumor 20975948
ENSG00000096696 DSP cancer 21082774
ENSG00000096696 DSP tumor 22069554
ENSG00000096696 DSP tumours 2212065
ENSG00000096696 DSP cancer 22453032
ENSG00000096696 DSP tumor 22481945
ENSG00000096696 DSP tumor 22791817
ENSG00000096696 DSP tumors 22898789
ENSG00000096696 DSP cancer 22963885
ENSG00000096696 DSP oral cancer 23233820
ENSG00000096696 DSP tumor 2410318
ENSG00000096696 DSP cancer 24184795
ENSG00000096696 DSP lung cancer 24223161
ENSG00000096696 DSP Tumor 2423346
ENSG00000096696 DSP tumor 24260260
ENSG00000096696 DSP tumors 2437802
ENSG00000096696 DSP tumors 2442053
ENSG00000096696 DSP lung cancer 24751108
ENSG00000096696 DSP Childhood Cancer 25058607
ENSG00000096696 DSP tumor 26118837
ENSG00000096696 DSP basal-like breast cancer 26241740
ENSG00000096696 DSP prostate cancer 26259043
ENSG00000096696 DSP tumor 26441981
ENSG00000096696 DSP tumors 27351128
ENSG00000096696 DSP cancer 27707353
ENSG00000096696 DSP Cancer 27881474
ENSG00000096696 DSP Lung cancer 27999279
ENSG00000096696 DSP ovarian cancer 28123876
ENSG00000096696 DSP tumors 28187001
ENSG00000096696 DSP gastric cancer 2831906
ENSG00000096696 DSP tumors 28323918
ENSG00000096696 DSP tumors 2847570
ENSG00000096696 DSP HNSCC 29157176
ENSG00000096696 DSP cancer 29373494
ENSG00000096696 DSP tumour 29402961
ENSG00000096696 DSP tumor 29499219
ENSG00000096696 DSP lung cancer 29517586
ENSG00000096696 DSP tumor 29587367
ENSG00000096696 DSP cancer 29669982
ENSG00000096696 DSP Tumor 2981372
ENSG00000096696 DSP tumor 29855376
ENSG00000096696 DSP tumor 30076294
ENSG00000096696 DSP tumor 30400822
ENSG00000096696 DSP cancer 30479833
ENSG00000096696 DSP tumour 30566430
ENSG00000096696 DSP tumors 31214676
ENSG00000096696 DSP breast cancer 31375149
ENSG00000096696 DSP gastric cancer 31484163
ENSG00000096696 DSP cancer 31501460
ENSG00000096696 DSP tumor 31502169
ENSG00000096696 DSP luminal breast cancer 31636386
ENSG00000096696 DSP tumor 31703602
ENSG00000096696 DSP tumor 31896964
ENSG00000096696 DSP tumor 31896965
ENSG00000096696 DSP tumors 31934531
ENSG00000096696 DSP tumors 3290868
ENSG00000096696 DSP tumours 3323433
ENSG00000096696 DSP tumors 3531717
ENSG00000096696 DSP tumor 3548408
ENSG00000096696 DSP tumor 3674283
ENSG00000096696 DSP tumor 6340102
ENSG00000096696 DSP tumors 6387275
ENSG00000096696 DSP ovarian tumor 7527220
ENSG00000096696 DSP tumors 7656386
ENSG00000096696 DSP tumour 7821894
ENSG00000096696 DSP breast cancer 7881109
ENSG00000096696 DSP Merkel cell tumor 8120418
ENSG00000096696 DSP tumor 8381787
ENSG00000096696 DSP tumor 9109790
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000096696 DSP MESO 0.023 low
ENSG00000096696 DSP PAAD 0.044 high
ENSG00000096696 DSP UCEC 0.0063 high
ENSG00000096696 DSP LGG 0.038 high
ENSG00000096696 DSP LUSC 0.037 low
ENSG00000096696 DSP HNSC 0.0093 low
ENSG00000096696 DSP READ 0.011 low
ENSG00000096696 DSP KIRP 0.016 low
ENSG00000096696 DSP KICH 0.016 high
ENSG00000096696 DSP LUAD 0.0053 high
ENSG00000096696 DSP BLCA 0.00051 high
ENSG00000096696 DSP LAML 0.039 low
ENSG00000096696 DSP LIHC 0.05 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000096696 DSP LUSC Del 2.388761 0.087736 0.350549 0.263473
ENSG00000096696 DSP LUAD Amp 0.819748 0.120202 0.438456 0.383721
ENSG00000096696 DSP THYM Del 1.199597 0.053692 0.413516 0.211382
ENSG00000096696 DSP SARC Del 1.379796 0.141545 0.522860 0.319066
ENSG00000096696 DSP PAAD Del 2.560929 0.080022 0.353548 0.402174
ENSG00000096696 DSP ESCA Del 6.076772 0.217707 0.446403 0.331522
ENSG00000096696 DSP SKCM Amp 7.635369 0.304152 0.785148 0.569482
ENSG00000096696 DSP HNSC Del 0.995101 0.057866 0.373351 0.178161
ENSG00000096696 DSP LIHC Amp 2.493459 0.157074 0.751560 0.413514
ENSG00000096696 DSP BLCA Amp 4.786909 0.284439 0.533676 0.325980
ENSG00000096696 DSP BRCA Del 0.809241 0.064458 0.414658 0.162037
ENSG00000096696 DSP STAD Del 4.421905 0.103355 0.412652 0.190476
ENSG00000096696 DSP UVM Amp 5.139661 0.410285 1.204233 0.562500
ENSG00000096696 DSP OV Amp 8.033295 0.511433 0.784509 0.485320