Ensembl ID ENSG00000092964 Gene ID 1808 Accession 3014
Gene Symbol DPYSL2 Alias DRP2;N2A3;CRMP2;DRP-2;ULIP2;CRMP-2;DHPRP2;ULIP-2 Full Name dihydropyrimidinase like 2
Position 8 : 26514031 - 26658178 Length 144148 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

ENSG00000092964 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000092964 DPYSL2 0.73 2.07e-22 KIRC
ENSG00000092964 DPYSL2 -1.3 1.83e-68 BRCA
ENSG00000092964 DPYSL2 -1.5 2.88e-15 KICH
ENSG00000092964 DPYSL2 -2.8 3.95e-101 LUSC
ENSG00000092964 DPYSL2 -0.7 4.76e-11 PRAD
ENSG00000092964 DPYSL2 -1.6 1.13e-17 UCEC
ENSG00000092964 DPYSL2 -1.5 4.52e-43 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000092964 DPYSL2 cancer 18203259
ENSG00000092964 DPYSL2 tumor 18218617
ENSG00000092964 DPYSL2 cancer 19204725
ENSG00000092964 DPYSL2 lung cancer 23023514
ENSG00000092964 DPYSL2 breast cancer 23381229
ENSG00000092964 DPYSL2 tumor 23667495
ENSG00000092964 DPYSL2 tumors 24011394
ENSG00000092964 DPYSL2 tumors 24765134
ENSG00000092964 DPYSL2 GBM 24838487
ENSG00000092964 DPYSL2 colorectal cancer 25050539
ENSG00000092964 DPYSL2 tumors 25224486
ENSG00000092964 DPYSL2 tumour 26555036
ENSG00000092964 DPYSL2 tumours 28585546
ENSG00000092964 DPYSL2 prostate cancer 28651527
ENSG00000092964 DPYSL2 cancer 28660485
ENSG00000092964 DPYSL2 breast cancer 28731166
ENSG00000092964 DPYSL2 ovarian cancer 29396402
ENSG00000092964 DPYSL2 tumor 30587593
ENSG00000092964 DPYSL2 tumors 30816227
ENSG00000092964 DPYSL2 cancer 30915713
ENSG00000092964 DPYSL2 tumor 30969984
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000092964 DPYSL2 MESO 0.014 low
ENSG00000092964 DPYSL2 STAD 0.018 high
ENSG00000092964 DPYSL2 CHOL 0.024 low
ENSG00000092964 DPYSL2 UVM 0.007 low
ENSG00000092964 DPYSL2 PAAD 0.00012 low
ENSG00000092964 DPYSL2 UCEC 0.0026 high
ENSG00000092964 DPYSL2 THCA 0.0014 high
ENSG00000092964 DPYSL2 ACC 0.0012 high
ENSG00000092964 DPYSL2 LUSC 0.0012 high
ENSG00000092964 DPYSL2 HNSC 0.012 low
ENSG00000092964 DPYSL2 KIRP 0.014 low
ENSG00000092964 DPYSL2 LUAD 2e-04 low
ENSG00000092964 DPYSL2 PRAD 0.025 low
ENSG00000092964 DPYSL2 SKCM 0.012 low
ENSG00000092964 DPYSL2 CESC 0.0057 low
ENSG00000092964 DPYSL2 LIHC 0.006 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000092964 DPYSL2 LUSC Del 2.692767 0.090977 0.450567 0.658683
ENSG00000092964 DPYSL2 LUAD Del 1.852064 0.065672 0.451486 0.515504
ENSG00000092964 DPYSL2 READ Del 6.194671 0.172568 0.683513 0.593939
ENSG00000092964 DPYSL2 COAD Del 6.432688 0.090501 0.674004 0.430155
ENSG00000092964 DPYSL2 UCS Del 0.993070 0.226197 0.702239 0.553571
ENSG00000092964 DPYSL2 ESCA Del 0.789586 0.099439 0.471154 0.472826
ENSG00000092964 DPYSL2 LIHC Del 4.202021 0.112654 0.706626 0.702703
ENSG00000092964 DPYSL2 BLCA Del 3.878602 0.121798 0.514758 0.605392
ENSG00000092964 DPYSL2 BRCA Del 18.250121 0.143251 0.591545 0.533333
ENSG00000092964 DPYSL2 STAD Del 0.653924 0.059656 0.443690 0.303855
ENSG00000092964 DPYSL2 PRAD Del 22.824282 0.217410 0.575918 0.565041
ENSG00000092964 DPYSL2 UCEC Del 8.731697 0.112282 0.700756 0.215213
ENSG00000092964 DPYSL2 OV Del 28.911774 0.443157 0.761310 0.699482