Ensembl ID ENSG00000092199 Gene ID 3183 Accession 5035
Gene Symbol HNRNPC Alias C1;C2;HNRNP;HNRPC;SNRPC Full Name heterogeneous nuclear ribonucleoprotein C
Position 14 : 21209136 - 21269494 Length 60359 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

ENSG00000092199 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000092199 HNRNPC 0.49 5.29e-57 BRCA
ENSG00000092199 HNRNPC -0.6 4.69e-21 KICH
ENSG00000092199 HNRNPC 0.62 4.85e-26 LUSC
ENSG00000092199 HNRNPC 0.54 1.17e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000092199 HNRNPC tumor 17627933
ENSG00000092199 HNRNPC cancer 24379680
ENSG00000092199 HNRNPC breast cancer 25913416
ENSG00000092199 HNRNPC gastric cancer 26453116
ENSG00000092199 HNRNPC tumour 26774260
ENSG00000092199 HNRNPC breast cancer 29063053
ENSG00000092199 HNRNPC ovarian cancer 29899543
ENSG00000092199 HNRNPC breast cancer 30158112
ENSG00000092199 HNRNPC breast cancer 30389667
ENSG00000092199 HNRNPC testicular germ cell tumors 30903744
ENSG00000092199 HNRNPC COAD 31396313
ENSG00000092199 HNRNPC tumour 31632489
ENSG00000092199 HNRNPC gastric cancer 31681576
ENSG00000092199 HNRNPC cancer 31720080
ENSG00000092199 HNRNPC lung cancer 31775888
ENSG00000092199 HNRNPC colon cancer 31823961
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000092199 HNRNPC MESO 0.047 high
ENSG00000092199 HNRNPC SARC 0.00035 high
ENSG00000092199 HNRNPC CHOL 0.0057 low
ENSG00000092199 HNRNPC UVM 0.033 high
ENSG00000092199 HNRNPC PAAD 0.0026 high
ENSG00000092199 HNRNPC UCEC 0.04 low
ENSG00000092199 HNRNPC THCA 0.002 low
ENSG00000092199 HNRNPC ACC 0.00043 high
ENSG00000092199 HNRNPC LGG 0.00082 low
ENSG00000092199 HNRNPC LUSC 0.041 low
ENSG00000092199 HNRNPC HNSC 0.0036 high
ENSG00000092199 HNRNPC KIRP 0.00016 high
ENSG00000092199 HNRNPC KICH 0.014 high
ENSG00000092199 HNRNPC LUAD 0.00015 high
ENSG00000092199 HNRNPC THYM 0.028 low
ENSG00000092199 HNRNPC BRCA 0.0014 low
ENSG00000092199 HNRNPC ESCA 0.0064 high
ENSG00000092199 HNRNPC PRAD 0.027 high
ENSG00000092199 HNRNPC TGCT 0.0034 low
ENSG00000092199 HNRNPC BLCA 0.017 high
ENSG00000092199 HNRNPC LAML 0.035 high
ENSG00000092199 HNRNPC GBM 0.016 low
ENSG00000092199 HNRNPC SKCM 0.023 low
ENSG00000092199 HNRNPC CESC 0.008 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000092199 HNRNPC LUSC Del 1.428968 0.076066 0.360816 0.349301
ENSG00000092199 HNRNPC LUAD Amp 1.307272 0.133333 0.423601 0.319767
ENSG00000092199 HNRNPC KIRP Del 1.294553 0.033081 0.546491 0.173611
ENSG00000092199 HNRNPC ACC Amp 0.908712 0.273335 1.099683 0.300000
ENSG00000092199 HNRNPC READ Del 0.947544 0.079394 0.491519 0.418182
ENSG00000092199 HNRNPC GBM Del 5.463633 0.096069 0.598619 0.296360
ENSG00000092199 HNRNPC PAAD Del 0.915393 0.050014 0.424627 0.108696
ENSG00000092199 HNRNPC HNSC Del 1.120533 0.059318 0.413777 0.136015
ENSG00000092199 HNRNPC OV Amp 3.200603 0.408373 0.811859 0.243523