Ensembl ID ENSG00000090905 Gene ID 27327 Accession 11969
Gene Symbol TNRC6A Alias GW1;FAME6;GW182;TNRC6;CAGH26 Full Name trinucleotide repeat containing adaptor 6A
Position 16 : 24729651 - 24827632 Length 97982 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]

ENSG00000090905 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000090905 TNRC6A 1.02 2.22e-22 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000090905 TNRC6A colorectal cancers 20198652
ENSG00000090905 TNRC6A esophageal cancers 20402672
ENSG00000090905 TNRC6A tumors 23135352
ENSG00000090905 TNRC6A breast cancer 23224974
ENSG00000090905 TNRC6A cancer 29907771
ENSG00000090905 TNRC6A cancers 30038597
ENSG00000090905 TNRC6A tumor 31510013
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000090905 TNRC6A PAAD 0.0061 low
ENSG00000090905 TNRC6A LGG 0.00039 high
ENSG00000090905 TNRC6A LUSC 0.05 low
ENSG00000090905 TNRC6A HNSC 0.001 low
ENSG00000090905 TNRC6A READ 0.0081 low
ENSG00000090905 TNRC6A KIRP 0.044 low
ENSG00000090905 TNRC6A KICH 0.0025 low
ENSG00000090905 TNRC6A LUAD 0.0067 low
ENSG00000090905 TNRC6A PCPG 0.0079 low
ENSG00000090905 TNRC6A COAD 0.0098 high
ENSG00000090905 TNRC6A ESCA 0.0025 low
ENSG00000090905 TNRC6A OV 0.04 low
ENSG00000090905 TNRC6A KIRC 0.00095 high
ENSG00000090905 TNRC6A PRAD 0.0039 high
ENSG00000090905 TNRC6A GBM 0.024 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000090905 TNRC6A GBM Del 0.701941 0.051787 0.401495 0.154246
ENSG00000090905 TNRC6A BLCA Amp 2.314097 0.219161 0.637115 0.223039