Ensembl ID ENSG00000089597 Gene ID 23193 Accession 4138
Gene Symbol GANAB Alias G2AN;GIIA;PKD3;GLUII;GIIalpha Full Name glucosidase II alpha subunit
Position 11 : 62624826 - 62646726 Length 21901 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]

ENSG00000089597 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000089597 GANAB 0.61 3.22e-16 HNSC
ENSG00000089597 GANAB 0.40 4.96e-18 BRCA
ENSG00000089597 GANAB 0.61 1.45e-21 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000089597 GANAB tumor 21459849
ENSG00000089597 GANAB cancer 21642380
ENSG00000089597 GANAB tumor 30301907
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000089597 GANAB STAD 0.039 low
ENSG00000089597 GANAB PAAD 0.0013 high
ENSG00000089597 GANAB HNSC 0.029 high
ENSG00000089597 GANAB READ 0.012 low
ENSG00000089597 GANAB KIRP 0.027 high
ENSG00000089597 GANAB LUAD 0.0024 high
ENSG00000089597 GANAB PCPG 0.045 high
ENSG00000089597 GANAB UCS 0.049 low
ENSG00000089597 GANAB PRAD 0.04 low
ENSG00000089597 GANAB TGCT 0.017 high
ENSG00000089597 GANAB BLCA 0.0028 high
ENSG00000089597 GANAB LAML 0.012 low
ENSG00000089597 GANAB GBM 0.017 high
ENSG00000089597 GANAB SKCM 0.049 high
ENSG00000089597 GANAB CESC 0.0015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000089597 GANAB HNSC Amp 1.287693 0.131420 0.403898 0.235632
ENSG00000089597 GANAB BRCA Del 1.477862 0.070472 0.426327 0.218519
ENSG00000089597 GANAB UCEC Amp 0.812488 0.105813 0.516370 0.115028