Ensembl ID ENSG00000089195 Gene ID 51605 Accession 20900
Gene Symbol TRMT6 Alias GCD10;CGI-09;Gcd10p Full Name tRNA methyltransferase 6 non-catalytic subunit
Position 20 : 5937228 - 5950558 Length 13331 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

ENSG00000089195 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000089195 TRMT6 -0.6 1.22e-33 KIRC
ENSG00000089195 TRMT6 0.48 5.34e-20 BRCA
ENSG00000089195 TRMT6 1.03 4.38e-24 COAD
ENSG00000089195 TRMT6 1.13 9.31e-41 LUSC
ENSG00000089195 TRMT6 -0.5 2.20e-17 PRAD
ENSG00000089195 TRMT6 0.62 7.85e-16 LIHC
ENSG00000089195 TRMT6 1.04 7.13e-18 STAD
ENSG00000089195 TRMT6 0.56 5.76e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000089195 TRMT6 pancreatic cancer 22767216
ENSG00000089195 TRMT6 Colon Cancers 28803425
ENSG00000089195 TRMT6 cancer 30588513
ENSG00000089195 TRMT6 cancers 31352195
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000089195 TRMT6 MESO 0.019 high
ENSG00000089195 TRMT6 SARC 0.0017 high
ENSG00000089195 TRMT6 STAD 0.016 low
ENSG00000089195 TRMT6 PAAD 0.049 low
ENSG00000089195 TRMT6 THCA 0.0049 high
ENSG00000089195 TRMT6 ACC 0.0099 high
ENSG00000089195 TRMT6 READ 0.05 low
ENSG00000089195 TRMT6 KIRP 0.00016 high
ENSG00000089195 TRMT6 KICH 0.011 high
ENSG00000089195 TRMT6 COAD 0.011 high
ENSG00000089195 TRMT6 UCS 0.044 high
ENSG00000089195 TRMT6 ESCA 0.0033 high
ENSG00000089195 TRMT6 DLBC 0.0092 low
ENSG00000089195 TRMT6 KIRC 0.0032 high
ENSG00000089195 TRMT6 BLCA 0.014 low
ENSG00000089195 TRMT6 LAML 0.0014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000089195 TRMT6 READ Del 1.124057 0.084644 0.568421 0.290909
ENSG00000089195 TRMT6 COAD Del 1.043114 0.046331 0.549942 0.179601