Ensembl ID ENSG00000089157 Gene ID 6175 Accession 10371
Gene Symbol RPLP0 Alias P0;LP0;L10E;RPP0;uL10;PRLP0 Full Name ribosomal protein lateral stalk subunit P0
Position 12 : 120196699 - 120201235 Length 4537 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

ENSG00000089157 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000089157 RPLP0 1.05 8.85e-35 KIRC
ENSG00000089157 RPLP0 0.97 1.31e-21 LUSC
ENSG00000089157 RPLP0 2.92 9.03e-22 GBM
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000089157 RPLP0 tumor 16215318
ENSG00000089157 RPLP0 tumour 18042273
ENSG00000089157 RPLP0 cancer 18211679
ENSG00000089157 RPLP0 tumors 18423048
ENSG00000089157 RPLP0 breast tumors 19544972
ENSG00000089157 RPLP0 breast cancer 21420492
ENSG00000089157 RPLP0 breast cancer 21702980
ENSG00000089157 RPLP0 cancer 23054956
ENSG00000089157 RPLP0 tumors 24252460
ENSG00000089157 RPLP0 cancer 24313945
ENSG00000089157 RPLP0 ovarian cancer 24776823
ENSG00000089157 RPLP0 colorectal cancer 24859296
ENSG00000089157 RPLP0 breast cancer 24911873
ENSG00000089157 RPLP0 tumor 25225161
ENSG00000089157 RPLP0 gastric cancer 25433997
ENSG00000089157 RPLP0 small cell lung cancer 25573171
ENSG00000089157 RPLP0 tumor 27832777
ENSG00000089157 RPLP0 AML 29286103
ENSG00000089157 RPLP0 tumors 30538116
ENSG00000089157 RPLP0 cervical cancer 31131438
ENSG00000089157 RPLP0 cancer 31712650
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000089157 RPLP0 SARC 0.017 high
ENSG00000089157 RPLP0 UVM 0.039 low
ENSG00000089157 RPLP0 UCEC 0.0051 low
ENSG00000089157 RPLP0 LUSC 0.04 low
ENSG00000089157 RPLP0 LUAD 0.036 high
ENSG00000089157 RPLP0 PCPG 0.00025 high
ENSG00000089157 RPLP0 BRCA 0.0015 low
ENSG00000089157 RPLP0 ESCA 0.038 low
ENSG00000089157 RPLP0 OV 0.00017 high
ENSG00000089157 RPLP0 LAML 0.0022 high
ENSG00000089157 RPLP0 GBM 0.03 low
ENSG00000089157 RPLP0 SKCM 0.0068 high
ENSG00000089157 RPLP0 LIHC 0.004 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000089157 RPLP0 PAAD Del 1.194446 0.055898 0.345588 0.222826
ENSG00000089157 RPLP0 LIHC Del 0.706077 0.065252 0.409786 0.132432
ENSG00000089157 RPLP0 BRCA Del 2.819053 0.080196 0.369908 0.192593
ENSG00000089157 RPLP0 OV Del 2.250501 0.206994 0.556102 0.312608