Ensembl ID
ENSG00000088205
Gene ID
8886
Accession
2741
Gene Symbol
DDX18
Alias
Has1;MrDb
Full Name
DEAD-box helicase 18
Position
2 : 117814691 - 117832377
Length
17687 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs rRNA RBP type
Canonical_RBPs
Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008]
ENSG00000088205 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000088205
DDX18
0.65
2.45e-19
COAD
ENSG00000088205
DDX18
0.59
4.03e-19
LUSC
ENSG00000088205
DDX18
0.65
2.20e-15
STAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000088205
DDX18
tumor
18351129
ENSG00000088205
DDX18
acute myeloid leukemia (AML)
21653321
ENSG00000088205
DDX18
breast cancer
25284587
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000088205
DDX18
MESO
0.00049
high
show
ENSG00000088205
DDX18
UVM
0.038
high
show
ENSG00000088205
DDX18
PAAD
0.0035
high
show
ENSG00000088205
DDX18
UCEC
0.00025
high
show
ENSG00000088205
DDX18
LGG
0.00066
high
show
ENSG00000088205
DDX18
LUSC
0.00067
low
show
ENSG00000088205
DDX18
HNSC
0.0014
high
show
ENSG00000088205
DDX18
KICH
0.021
high
show
ENSG00000088205
DDX18
PCPG
0.017
high
show
ENSG00000088205
DDX18
THYM
0.039
low
show
ENSG00000088205
DDX18
UCS
0.025
high
show
ENSG00000088205
DDX18
ESCA
0.025
low
show
ENSG00000088205
DDX18
PRAD
0.031
low
show
ENSG00000088205
DDX18
BLCA
0.033
high
show
ENSG00000088205
DDX18
SKCM
0.015
low
show
ENSG00000088205
DDX18
CESC
0.02
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000088205
DDX18
ESCA
Amp
1.775114
0.325366
0.629918
0.331522
ENSG00000088205
DDX18
PRAD
Del
2.918340
0.097262
0.474058
0.107724
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