Ensembl ID ENSG00000088205 Gene ID 8886 Accession 2741
Gene Symbol DDX18 Alias Has1;MrDb Full Name DEAD-box helicase 18
Position 2 : 117814691 - 117832377 Length 17687 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008]

ENSG00000088205 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000088205 DDX18 0.65 2.45e-19 COAD
ENSG00000088205 DDX18 0.59 4.03e-19 LUSC
ENSG00000088205 DDX18 0.65 2.20e-15 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000088205 DDX18 tumor 18351129
ENSG00000088205 DDX18 acute myeloid leukemia (AML) 21653321
ENSG00000088205 DDX18 breast cancer 25284587
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000088205 DDX18 MESO 0.00049 high
ENSG00000088205 DDX18 UVM 0.038 high
ENSG00000088205 DDX18 PAAD 0.0035 high
ENSG00000088205 DDX18 UCEC 0.00025 high
ENSG00000088205 DDX18 LGG 0.00066 high
ENSG00000088205 DDX18 LUSC 0.00067 low
ENSG00000088205 DDX18 HNSC 0.0014 high
ENSG00000088205 DDX18 KICH 0.021 high
ENSG00000088205 DDX18 PCPG 0.017 high
ENSG00000088205 DDX18 THYM 0.039 low
ENSG00000088205 DDX18 UCS 0.025 high
ENSG00000088205 DDX18 ESCA 0.025 low
ENSG00000088205 DDX18 PRAD 0.031 low
ENSG00000088205 DDX18 BLCA 0.033 high
ENSG00000088205 DDX18 SKCM 0.015 low
ENSG00000088205 DDX18 CESC 0.02 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000088205 DDX18 ESCA Amp 1.775114 0.325366 0.629918 0.331522
ENSG00000088205 DDX18 PRAD Del 2.918340 0.097262 0.474058 0.107724