Ensembl ID ENSG00000087274 Gene ID 118 Accession 243
Gene Symbol ADD1 Alias ADDA Full Name adducin 1
Position 4 : 2843844 - 2930076 Length 86233 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]

ENSG00000087274 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000087274 -0.9 4.06e-20 BLCA
ENSG00000087274 -0.4 2.82e-34 BRCA
ENSG00000087274 -0.8 2.96e-58 COAD
ENSG00000087274 -0.8 2.46e-15 READ
ENSG00000087274 -0.9 3.78e-47 LUSC
ENSG00000087274 -0.3 2.37e-23 PRAD
ENSG00000087274 -0.7 1.23e-15 STAD
ENSG00000087274 -0.8 1.52e-33 UCEC
ENSG00000087274 -0.7 8.82e-45 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000087274 breast cancer 11278421
ENSG00000087274 tumour 22415278
ENSG00000087274 gastric cancer 23985264
ENSG00000087274 breast cancers 25803781
ENSG00000087274 colorectal cancer 25816007
ENSG00000087274 tumor 26279304
ENSG00000087274 cancer 27679486
ENSG00000087274 tumor 28032742
ENSG00000087274 tumor 28368404
ENSG00000087274 colorectal cancer 28476036
ENSG00000087274 tumor 28628114
ENSG00000087274 lung cancer 31399647
ENSG00000087274 tumor 31548578
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000087274 PAAD 0.00065 low
ENSG00000087274 UCEC 0.0014 low
ENSG00000087274 LUSC 0.0073 high
ENSG00000087274 HNSC 0.028 low
ENSG00000087274 READ 0.0036 high
ENSG00000087274 PCPG 0.02 low
ENSG00000087274 THYM 0.048 low
ENSG00000087274 COAD 0.019 low
ENSG00000087274 UCS 0.029 low
ENSG00000087274 ESCA 0.0063 low
ENSG00000087274 DLBC 0.0098 high
ENSG00000087274 PRAD 0.031 low
ENSG00000087274 BLCA 0.005 low
ENSG00000087274 LAML 0.015 high
ENSG00000087274 SKCM 0.016 low
ENSG00000087274 LIHC 0.0044 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000087274 ESCA Del 1.208557 0.111207 0.440553 0.559783
ENSG00000087274 HNSC Del 2.207486 0.070310 0.421513 0.392720
ENSG00000087274 UCEC Del 0.855016 0.049814 0.488825 0.166976
ENSG00000087274 OV Amp 1.175317 0.346138 0.727556 0.255613