Ensembl ID
ENSG00000087274
Gene ID
118
Accession
243
Gene Symbol
ADD1
Alias
ADDA
Full Name
adducin 1
Position
4 : 2843844 - 2930076
Length
86233 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
ENSG00000087274 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000087274
-0.9
4.06e-20
BLCA
ENSG00000087274
-0.4
2.82e-34
BRCA
ENSG00000087274
-0.8
2.96e-58
COAD
ENSG00000087274
-0.8
2.46e-15
READ
ENSG00000087274
-0.9
3.78e-47
LUSC
ENSG00000087274
-0.3
2.37e-23
PRAD
ENSG00000087274
-0.7
1.23e-15
STAD
ENSG00000087274
-0.8
1.52e-33
UCEC
ENSG00000087274
-0.7
8.82e-45
LUAD
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000087274
PAAD
0.00065
low
show
ENSG00000087274
UCEC
0.0014
low
show
ENSG00000087274
LUSC
0.0073
high
show
ENSG00000087274
HNSC
0.028
low
show
ENSG00000087274
READ
0.0036
high
show
ENSG00000087274
PCPG
0.02
low
show
ENSG00000087274
THYM
0.048
low
show
ENSG00000087274
COAD
0.019
low
show
ENSG00000087274
UCS
0.029
low
show
ENSG00000087274
ESCA
0.0063
low
show
ENSG00000087274
DLBC
0.0098
high
show
ENSG00000087274
PRAD
0.031
low
show
ENSG00000087274
BLCA
0.005
low
show
ENSG00000087274
LAML
0.015
high
show
ENSG00000087274
SKCM
0.016
low
show
ENSG00000087274
LIHC
0.0044
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000087274
ESCA
Del
1.208557
0.111207
0.440553
0.559783
ENSG00000087274
HNSC
Del
2.207486
0.070310
0.421513
0.392720
ENSG00000087274
UCEC
Del
0.855016
0.049814
0.488825
0.166976
ENSG00000087274
OV
Amp
1.175317
0.346138
0.727556
0.255613
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