Ensembl ID
ENSG00000087077
Gene ID
7205
Accession
12311
Gene Symbol
TRIP6
Alias
OIP1;OIP-1;ZRP-1;TRIP-6;TRIP6i2
Full Name
thyroid hormone receptor interactor 6
Position
7 : 100867387 - 100873454
Length
6068 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
ENSG00000087077 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000087077
TRIP6
1.18
9.35e-12
COAD
ENSG00000087077
TRIP6
0.84
2.63e-14
LUSC
ENSG00000087077
TRIP6
-0.9
9.45e-13
PRAD
ENSG00000087077
TRIP6
2.04
6.59e-11
GBM
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000087077
TRIP6
ovarian cancer
14688263
ENSG00000087077
TRIP6
colon tumors
19017743
ENSG00000087077
TRIP6
cancer
21689746
ENSG00000087077
TRIP6
cancer
22054418
ENSG00000087077
TRIP6
tumor
23339869
ENSG00000087077
TRIP6
nasopharyngeal cancer
23576104
ENSG00000087077
TRIP6
tumor
26298725
ENSG00000087077
TRIP6
ovarian cancer
27134758
ENSG00000087077
TRIP6
tumor
29080747
ENSG00000087077
TRIP6
tumor
30061182
ENSG00000087077
TRIP6
colorectal cancer
31018940
ENSG00000087077
TRIP6
colorectal cancer
31029422
ENSG00000087077
TRIP6
tumor
31354238
ENSG00000087077
TRIP6
tumor
31424277
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000087077
TRIP6
MESO
0.018
low
show
ENSG00000087077
TRIP6
STAD
0.046
low
show
ENSG00000087077
TRIP6
CHOL
0.037
low
show
ENSG00000087077
TRIP6
UVM
0.0036
low
show
ENSG00000087077
TRIP6
PAAD
0.0055
high
show
ENSG00000087077
TRIP6
UCEC
0.0042
high
show
ENSG00000087077
TRIP6
LUSC
0.015
low
show
ENSG00000087077
TRIP6
HNSC
0.027
high
show
ENSG00000087077
TRIP6
KICH
0.0016
low
show
ENSG00000087077
TRIP6
THYM
0.029
high
show
ENSG00000087077
TRIP6
BRCA
8e-04
low
show
ENSG00000087077
TRIP6
COAD
0.0013
high
show
ENSG00000087077
TRIP6
ESCA
0.044
low
show
ENSG00000087077
TRIP6
OV
0.024
high
show
ENSG00000087077
TRIP6
KIRC
0.0079
high
show
ENSG00000087077
TRIP6
PRAD
0.017
low
show
ENSG00000087077
TRIP6
BLCA
0.042
high
show
ENSG00000087077
TRIP6
LAML
0.0068
high
show
ENSG00000087077
TRIP6
GBM
0.0015
high
show
ENSG00000087077
TRIP6
SKCM
0.024
high
show
ENSG00000087077
TRIP6
LIHC
0.0074
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000087077
TRIP6
PAAD
Amp
0.633560
0.078080
0.418628
0.288043
ENSG00000087077
TRIP6
ESCA
Amp
4.843906
0.470086
0.713803
0.548913
ENSG00000087077
TRIP6
HNSC
Amp
5.826481
0.216548
0.587086
0.319923
ENSG00000087077
TRIP6
STAD
Amp
4.114880
0.219194
0.547801
0.433107
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