Ensembl ID ENSG00000086504 Gene ID 10573 Accession 14484
Gene Symbol MRPL28 Alias p15;MAAT1;bL28m Full Name mitochondrial ribosomal protein L28
Position 16 : 366969 - 371289 Length 4321 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]

ENSG00000086504 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000086504 MRPL28 0.85 1.72e-28 BRCA
ENSG00000086504 MRPL28 0.61 2.12e-15 LUSC
ENSG00000086504 MRPL28 0.94 6.57e-12 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000086504 MRPL28 MESO 0.0045 high
ENSG00000086504 MRPL28 CHOL 0.00053 high
ENSG00000086504 MRPL28 UVM 0.0074 high
ENSG00000086504 MRPL28 PAAD 0.026 low
ENSG00000086504 MRPL28 ACC 0.0097 high
ENSG00000086504 MRPL28 LGG 0.00026 low
ENSG00000086504 MRPL28 LUSC 0.015 high
ENSG00000086504 MRPL28 KICH 0.0071 low
ENSG00000086504 MRPL28 LUAD 0.0054 high
ENSG00000086504 MRPL28 PCPG 0.011 low
ENSG00000086504 MRPL28 UCS 2e-04 high
ENSG00000086504 MRPL28 KIRC 0.009 high
ENSG00000086504 MRPL28 LAML 0.00024 high
ENSG00000086504 MRPL28 GBM 0.022 high
ENSG00000086504 MRPL28 CESC 0.0037 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency