Ensembl ID ENSG00000085999 Gene ID 8438 Accession 9826
Gene Symbol RAD54L Alias HR54;hHR54;RAD54A;hRAD54 Full Name RAD54 like
Position 1 : 46247688 - 46278480 Length 30793 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]

ENSG00000085999 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000085999 2.49 1.47e-58 KIRC
ENSG00000085999 1.60 1.20e-43 HNSC
ENSG00000085999 2.25 8.77e-24 BLCA
ENSG00000085999 2.79 1.09e-131 BRCA
ENSG00000085999 1.48 6.83e-42 COAD
ENSG00000085999 4.22 8.60e-284 LUSC
ENSG00000085999 1.84 2.03e-21 KIRP
ENSG00000085999 3.36 5.43e-51 LIHC
ENSG00000085999 1.73 3.19e-25 STAD
ENSG00000085999 3.37 1.47e-86 UCEC
ENSG00000085999 2.03 9.04e-17 ESCA
ENSG00000085999 4.53 7.58e-25 CHOL
ENSG00000085999 4.89 1.24e-39 CESC
ENSG00000085999 3.28 5.05e-92 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000085999 tumor 10326867
ENSG00000085999 tumor 10451706
ENSG00000085999 tumors 10640146
ENSG00000085999 breast tumors 9192813
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000085999 SARC 0.00061 high
ENSG00000085999 STAD 0.0079 low
ENSG00000085999 PAAD 0.00058 high
ENSG00000085999 UCEC 0.0055 high
ENSG00000085999 HNSC 0.00089 low
ENSG00000085999 READ 0.0039 low
ENSG00000085999 LUAD 0.00057 high
ENSG00000085999 PCPG 0.0074 high
ENSG00000085999 THYM 0.0038 low
ENSG00000085999 BRCA 0.032 high
ENSG00000085999 COAD 0.041 high
ENSG00000085999 UCS 0.00056 low
ENSG00000085999 OV 0.048 low
ENSG00000085999 LAML 0.006 high
ENSG00000085999 SKCM 0.025 high
ENSG00000085999 CESC 0.0016 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000085999 CHOL Del 1.033657 0.234574 0.607663 0.277778
ENSG00000085999 KIRP Del 0.646972 0.026314 0.603087 0.135417
ENSG00000085999 LIHC Del 1.052424 0.071396 0.487340 0.278378
ENSG00000085999 PCPG Del 3.860630 0.114948 0.677432 0.666667
ENSG00000085999 UCEC Amp 1.272788 0.117554 0.538059 0.131725
ENSG00000085999 UVM Del 1.063142 0.074432 0.811138 0.287500
ENSG00000085999 OV Amp 5.155346 0.454249 0.642092 0.442142