Ensembl ID
ENSG00000084073
Gene ID
10269
Accession
12877
Gene Symbol
ZMPSTE24
Alias
HGPS;PRO1;FACE1;RSDM1;STE24;FACE-1;Ste24p
Full Name
zinc metallopeptidase STE24
Position
1 : 40258041 - 40294180
Length
36140 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
ENSG00000084073 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000084073
ZMPSTE24
-0.5
7.69e-22
KIRC
ENSG00000084073
ZMPSTE24
0.53
1.12e-27
BRCA
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000084073
ZMPSTE24
tumor
19680556
ENSG00000084073
ZMPSTE24
cancer
23917225
ENSG00000084073
ZMPSTE24
pancreatic cancer
24533689
ENSG00000084073
ZMPSTE24
colorectal cancers
27729169
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000084073
ZMPSTE24
SARC
0.011
high
show
ENSG00000084073
ZMPSTE24
STAD
0.041
low
show
ENSG00000084073
ZMPSTE24
UVM
1e-04
high
show
ENSG00000084073
ZMPSTE24
PAAD
0.043
high
show
ENSG00000084073
ZMPSTE24
UCEC
0.046
high
show
ENSG00000084073
ZMPSTE24
ACC
0.0075
high
show
ENSG00000084073
ZMPSTE24
HNSC
0.05
high
show
ENSG00000084073
ZMPSTE24
KIRP
0.0048
high
show
ENSG00000084073
ZMPSTE24
KICH
0.015
high
show
ENSG00000084073
ZMPSTE24
BRCA
0.042
high
show
ENSG00000084073
ZMPSTE24
COAD
0.0034
low
show
ENSG00000084073
ZMPSTE24
UCS
0.046
high
show
ENSG00000084073
ZMPSTE24
ESCA
0.0012
high
show
ENSG00000084073
ZMPSTE24
OV
0.0049
low
show
ENSG00000084073
ZMPSTE24
DLBC
0.034
high
show
ENSG00000084073
ZMPSTE24
PRAD
0.047
high
show
ENSG00000084073
ZMPSTE24
BLCA
0.037
low
show
ENSG00000084073
ZMPSTE24
GBM
0.0016
low
show
ENSG00000084073
ZMPSTE24
CESC
0.013
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000084073
ZMPSTE24
CHOL
Del
1.366964
0.267655
0.616490
0.277778
ENSG00000084073
ZMPSTE24
LUAD
Amp
1.287956
0.132857
0.417630
0.271318
ENSG00000084073
ZMPSTE24
KIRP
Del
1.051437
0.030450
0.601841
0.138889
ENSG00000084073
ZMPSTE24
ESCA
Amp
1.479907
0.309044
0.811080
0.195652
ENSG00000084073
ZMPSTE24
LIHC
Del
2.921431
0.097731
0.508427
0.297297
ENSG00000084073
ZMPSTE24
PCPG
Del
1.415567
0.073513
0.676188
0.629630
ENSG00000084073
ZMPSTE24
BLCA
Amp
5.976423
0.310736
0.696308
0.247549
ENSG00000084073
ZMPSTE24
UCEC
Amp
2.604956
0.144178
0.613635
0.129870
ENSG00000084073
ZMPSTE24
UVM
Del
1.628635
0.096085
0.809086
0.300000
ENSG00000084073
ZMPSTE24
OV
Amp
22.702867
0.731626
0.798526
0.507772
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.