Ensembl ID ENSG00000084073 Gene ID 10269 Accession 12877
Gene Symbol ZMPSTE24 Alias HGPS;PRO1;FACE1;RSDM1;STE24;FACE-1;Ste24p Full Name zinc metallopeptidase STE24
Position 1 : 40258041 - 40294180 Length 36140 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]

ENSG00000084073 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000084073 ZMPSTE24 -0.5 7.69e-22 KIRC
ENSG00000084073 ZMPSTE24 0.53 1.12e-27 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000084073 ZMPSTE24 tumor 19680556
ENSG00000084073 ZMPSTE24 cancer 23917225
ENSG00000084073 ZMPSTE24 pancreatic cancer 24533689
ENSG00000084073 ZMPSTE24 colorectal cancers 27729169
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000084073 ZMPSTE24 SARC 0.011 high
ENSG00000084073 ZMPSTE24 STAD 0.041 low
ENSG00000084073 ZMPSTE24 UVM 1e-04 high
ENSG00000084073 ZMPSTE24 PAAD 0.043 high
ENSG00000084073 ZMPSTE24 UCEC 0.046 high
ENSG00000084073 ZMPSTE24 ACC 0.0075 high
ENSG00000084073 ZMPSTE24 HNSC 0.05 high
ENSG00000084073 ZMPSTE24 KIRP 0.0048 high
ENSG00000084073 ZMPSTE24 KICH 0.015 high
ENSG00000084073 ZMPSTE24 BRCA 0.042 high
ENSG00000084073 ZMPSTE24 COAD 0.0034 low
ENSG00000084073 ZMPSTE24 UCS 0.046 high
ENSG00000084073 ZMPSTE24 ESCA 0.0012 high
ENSG00000084073 ZMPSTE24 OV 0.0049 low
ENSG00000084073 ZMPSTE24 DLBC 0.034 high
ENSG00000084073 ZMPSTE24 PRAD 0.047 high
ENSG00000084073 ZMPSTE24 BLCA 0.037 low
ENSG00000084073 ZMPSTE24 GBM 0.0016 low
ENSG00000084073 ZMPSTE24 CESC 0.013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000084073 ZMPSTE24 CHOL Del 1.366964 0.267655 0.616490 0.277778
ENSG00000084073 ZMPSTE24 LUAD Amp 1.287956 0.132857 0.417630 0.271318
ENSG00000084073 ZMPSTE24 KIRP Del 1.051437 0.030450 0.601841 0.138889
ENSG00000084073 ZMPSTE24 ESCA Amp 1.479907 0.309044 0.811080 0.195652
ENSG00000084073 ZMPSTE24 LIHC Del 2.921431 0.097731 0.508427 0.297297
ENSG00000084073 ZMPSTE24 PCPG Del 1.415567 0.073513 0.676188 0.629630
ENSG00000084073 ZMPSTE24 BLCA Amp 5.976423 0.310736 0.696308 0.247549
ENSG00000084073 ZMPSTE24 UCEC Amp 2.604956 0.144178 0.613635 0.129870
ENSG00000084073 ZMPSTE24 UVM Del 1.628635 0.096085 0.809086 0.300000
ENSG00000084073 ZMPSTE24 OV Amp 22.702867 0.731626 0.798526 0.507772