Ensembl ID ENSG00000083312 Gene ID 3842 Accession 6401
Gene Symbol TNPO1 Alias MIP;TRN;IPO2;MIP1;KPNB2 Full Name transportin 1
Position 5 : 72816312 - 72916733 Length 100422 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018]

ENSG00000083312 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000083312 TNPO1 cancer 18026834
ENSG00000083312 TNPO1 breast cancer 21050422
ENSG00000083312 TNPO1 cancer 21847406
ENSG00000083312 TNPO1 tumor 22595208
ENSG00000083312 TNPO1 Metastatic Prostate Cancer 23468933
ENSG00000083312 TNPO1 tumors 24041225
ENSG00000083312 TNPO1 breast cancer 24939415
ENSG00000083312 TNPO1 cancer 26864452
ENSG00000083312 TNPO1 breast cancer 29051499
ENSG00000083312 TNPO1 cancer 29370181
ENSG00000083312 TNPO1 tumor 31561101
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000083312 TNPO1 MESO 0.0035 high
ENSG00000083312 TNPO1 SARC 0.027 high
ENSG00000083312 TNPO1 UVM 2e-04 high
ENSG00000083312 TNPO1 THCA 0.0041 high
ENSG00000083312 TNPO1 HNSC 0.0051 high
ENSG00000083312 TNPO1 READ 0.0055 low
ENSG00000083312 TNPO1 KIRP 0.0051 high
ENSG00000083312 TNPO1 KICH 0.00025 high
ENSG00000083312 TNPO1 LUAD 0.00037 high
ENSG00000083312 TNPO1 PCPG 0.045 high
ENSG00000083312 TNPO1 COAD 0.0037 high
ENSG00000083312 TNPO1 ESCA 0.024 high
ENSG00000083312 TNPO1 OV 0.0033 high
ENSG00000083312 TNPO1 KIRC 0.0034 low
ENSG00000083312 TNPO1 TGCT 0.0012 low
ENSG00000083312 TNPO1 BLCA 0.00047 high
ENSG00000083312 TNPO1 LAML 0.0011 low
ENSG00000083312 TNPO1 SKCM 0.0014 low
ENSG00000083312 TNPO1 CESC 0.013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000083312 TNPO1 LUSC Del 2.818261 0.092274 0.404959 0.766467
ENSG00000083312 TNPO1 LUAD Del 2.342875 0.070708 0.338528 0.395349
ENSG00000083312 TNPO1 CESC Del 0.812093 0.068996 0.470438 0.244068
ENSG00000083312 TNPO1 COAD Del 2.512752 0.060974 0.384674 0.241685
ENSG00000083312 TNPO1 UCS Del 2.644146 0.347995 0.499781 0.535714
ENSG00000083312 TNPO1 PAAD Del 1.765578 0.066489 0.347030 0.173913
ENSG00000083312 TNPO1 ESCA Del 2.649705 0.149453 0.438457 0.619565
ENSG00000083312 TNPO1 HNSC Del 2.369902 0.071762 0.384994 0.417625
ENSG00000083312 TNPO1 BLCA Del 3.750447 0.120206 0.409566 0.507353
ENSG00000083312 TNPO1 BRCA Del 6.761580 0.101148 0.453136 0.267593
ENSG00000083312 TNPO1 STAD Del 7.382001 0.127659 0.393542 0.371882
ENSG00000083312 TNPO1 PRAD Del 18.913102 0.198266 0.563531 0.186992
ENSG00000083312 TNPO1 UCEC Del 8.102412 0.108466 0.511296 0.204082
ENSG00000083312 TNPO1 OV Del 77.857552 0.699889 0.676235 0.723661