Ensembl ID ENSG00000082258 Gene ID 905 Accession 1600
Gene Symbol CCNT2 Alias CYCT2 Full Name cyclin T2
Position 2 : 134918235 - 134959342 Length 41108 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Non-canonical_RBPs
Summary The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]

ENSG00000082258 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000082258 CCNT2 AML 24701579
ENSG00000082258 CCNT2 gastric cancers 29849811
ENSG00000082258 CCNT2 AML 31455838
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000082258 CCNT2 ACC 0.003 high
ENSG00000082258 CCNT2 LUSC 0.0086 low
ENSG00000082258 CCNT2 HNSC 0.0023 low
ENSG00000082258 CCNT2 READ 0.05 low
ENSG00000082258 CCNT2 KIRP 0.027 high
ENSG00000082258 CCNT2 LUAD 0.033 low
ENSG00000082258 CCNT2 PCPG 0.0027 high
ENSG00000082258 CCNT2 BRCA 0.015 low
ENSG00000082258 CCNT2 OV 0.014 low
ENSG00000082258 CCNT2 KIRC 0.021 high
ENSG00000082258 CCNT2 BLCA 0.00065 low
ENSG00000082258 CCNT2 GBM 0.014 low
ENSG00000082258 CCNT2 LIHC 0.021 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000082258 CCNT2 DLBC Del 0.821169 0.130820 0.513090 0.125000
ENSG00000082258 CCNT2 STAD Del 0.678868 0.060147 0.364535 0.120181
ENSG00000082258 CCNT2 PRAD Del 15.454238 0.180442 0.535636 0.176829