Ensembl ID ENSG00000080824 Gene ID 3320 Accession 5253
Gene Symbol HSP90AA1 Alias EL52;HSPN;LAP2;HSP86;HSPC1;HSPCA;Hsp89;Hsp90;LAP-2;HSP89A;HSP90A;HSP90N;Hsp103;HSPCAL1;HSPCAL4;HEL-S-65p Full Name heat shock protein 90 alpha family class A member 1
Position 14 : 102080742 - 102139699 Length 58958 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

ENSG00000080824 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000080824 -0.8 5.43e-31 KIRC
ENSG00000080824 0.47 1.12e-11 BRCA
ENSG00000080824 0.63 8.72e-13 COAD
ENSG00000080824 0.62 5.44e-13 LUSC
ENSG00000080824 0.98 1.36e-17 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000080824 tumors 14666454
ENSG00000080824 tumour 15756260
ENSG00000080824 tumor 16532261
ENSG00000080824 endometrial cancer 16951393
ENSG00000080824 cancer 17767061
ENSG00000080824 breast cancer 19014541
ENSG00000080824 endometrial cancer 19745797
ENSG00000080824 cancer 19995938
ENSG00000080824 prostate cancer 20626159
ENSG00000080824 tumour 20858068
ENSG00000080824 tumor 21127066
ENSG00000080824 breast cancer 22018398
ENSG00000080824 tumors 22083493
ENSG00000080824 breast cancer 22510516
ENSG00000080824 ovarian cancer 23135731
ENSG00000080824 cancer 23196876
ENSG00000080824 benign tumors 23599795
ENSG00000080824 lung cancer 23762832
ENSG00000080824 tumor 24066008
ENSG00000080824 non-small cell lung cancer 24511009
ENSG00000080824 uterine cancer 24596812
ENSG00000080824 cancer 25167922
ENSG00000080824 prostate cancer 25313363
ENSG00000080824 cancer 25375091
ENSG00000080824 lung cancer 26124566
ENSG00000080824 cancer 26328888
ENSG00000080824 cancer 26704341
ENSG00000080824 ovarian cancer 27026916
ENSG00000080824 bladder cancer 27034531
ENSG00000080824 Prostate cancer 27221337
ENSG00000080824 lung cancer 27356570
ENSG00000080824 cancer 27485604
ENSG00000080824 cancer 27809917
ENSG00000080824 tumors 28043142
ENSG00000080824 breast cancers 28051275
ENSG00000080824 cancer 28057171
ENSG00000080824 breast cancer 28081538
ENSG00000080824 tumor 28248256
ENSG00000080824 cancer 28255900
ENSG00000080824 lung cancer 28290473
ENSG00000080824 Warthin's tumor 28386459
ENSG00000080824 tumor 28468249
ENSG00000080824 head and neck cancer 28915052
ENSG00000080824 tumor 29088865
ENSG00000080824 breast cancer 29138518
ENSG00000080824 tumor 2925609
ENSG00000080824 cancers 29379595
ENSG00000080824 AML 29545342
ENSG00000080824 Prostate cancer 29703916
ENSG00000080824 laryngeal cancer 29755572
ENSG00000080824 tumor 29872313
ENSG00000080824 cancer 29882813
ENSG00000080824 tumor 30153855
ENSG00000080824 AML 30214614
ENSG00000080824 prostate cancer 30255424
ENSG00000080824 Cancer 30471108
ENSG00000080824 cancer 30982140
ENSG00000080824 cancers 31101846
ENSG00000080824 cancer 31273033
ENSG00000080824 tumor 31337655
ENSG00000080824 cancer 31508330
ENSG00000080824 ovarian cancer 31540229
ENSG00000080824 cancer 31567483
ENSG00000080824 cancer 31765670
ENSG00000080824 cancer 31814876
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000080824 esophageal squamous cell carcinoma missense_variant 0.7407% (5/675) 3 entries
ENSG00000080824 skin melanoma missense_variant 0.5171% (5/967) 1 entry
ENSG00000080824 colorectal adenocarcinoma sequence_alteration 2.197% (25/1138) 1 entry
ENSG00000080824 papillary thyroid carcinoma missense_variant 0.7595% (3/395) 1 entry
ENSG00000080824 female breast carcinoma missense_variant 1.023% (4/391) 1 entry
ENSG00000080824 colorectal adenocarcinoma missense_variant 2.197% (25/1138) 2 entries
ENSG00000080824 hepatocellular carcinoma missense_variant 0.3337% (3/899) 1 entry
ENSG00000080824 ovarian serous adenocarcinoma missense_variant 0.7375% (5/678) 1 entry
ENSG00000080824 lung adenocarcinoma missense_variant 0.8197% (10/1220) 3 entries
ENSG00000080824 lung adenocarcinoma stop_gained 0.8197% (10/1220) 1 entry
ENSG00000080824 clear cell renal carcinoma missense_variant 0.6074% (8/1317) 1 entry
ENSG00000080824 squamous cell lung carcinoma missense_variant 0.8485% (7/825) 2 entries
ENSG00000080824 prostate adenocarcinoma sequence_alteration 1.582% (23/1454) 1 entry
ENSG00000080824 colon adenocarcinoma missense_variant 1.195% (9/753) 3 entries
ENSG00000080824 breast carcinoma missense_variant 0.4252% (6/1411) 1 entry
ENSG00000080824 gastric intestinal type adenocarcinoma missense_variant 5.882% (5/85) 2 entries
ENSG00000080824 brain glioblastoma sequence_alteration 0.54% (5/926) 1 entry
ENSG00000080824 colon adenocarcinoma sequence_alteration 1.195% (9/753) 2 entries
ENSG00000080824 bladder transitional cell carcinoma missense_variant 3.65% (5/137) 2 entries
ENSG00000080824 rectal adenocarcinoma sequence_alteration 1.81% (4/221) 1 entry
ENSG00000080824 melanoma missense_variant 4.95% (5/101) 1 entry
ENSG00000080824 gastric intestinal type adenocarcinoma frameshift_variant 5.882% (5/85) 1 entry
ENSG00000080824 HER2 Positive Breast Carcinoma missense_variant 3.636% (6/165) 2 entries
ENSG00000080824 gastric adenocarcinoma missense_variant 1.178% (8/679) 1 entry
ENSG00000080824 rectal adenocarcinoma missense_variant 1.81% (4/221) 1 entry
ENSG00000080824 chronic lymphocytic leukemia missense_variant 0.7883% (7/888) 1 entry
ENSG00000080824 Spinal Cord Astrocytoma missense_variant 25.0% (1/4) 1 entry
ENSG00000080824 ovarian serous adenocarcinoma frameshift_variant 0.7375% (5/678) 1 entry
ENSG00000080824 prostate carcinoma missense_variant 0.6198% (3/484) 1 entry
ENSG00000080824 colorectal adenocarcinoma frameshift_variant 2.197% (25/1138) 1 entry
ENSG00000080824 colorectal adenocarcinoma stop_gained 2.197% (25/1138) 1 entry
ENSG00000080824 papillary renal cell carcinoma missense_variant 0.5666% (2/353) 1 entry
ENSG00000080824 esophageal adenocarcinoma missense_variant 2.511% (11/438) 1 entry
ENSG00000080824 metaplastic breast carcinoma frameshift_variant 5.882% (3/51) 1 entry
ENSG00000080824 basal cell carcinoma sequence_alteration 1.724% (1/58) 1 entry
ENSG00000080824 breast ductal adenocarcinoma missense_variant 4.444% (26/585) 1 entry
ENSG00000080824 diffuse large B-cell lymphoma missense_variant 0.3289% (1/304) 1 entry
ENSG00000080824 colon adenocarcinoma conservative_inframe_deletion 1.195% (9/753) 1 entry
ENSG00000080824 anaplastic astrocytoma sequence_alteration 2.222% (1/45) 1 entry
ENSG00000080824 metaplastic breast carcinoma stop_gained 5.882% (3/51) 1 entry
ENSG00000080824 adenosquamous lung carcinoma missense_variant 9.091% (1/11) 1 entry
ENSG00000080824 melanoma frameshift_variant 4.95% (5/101) 1 entry
ENSG00000080824 prostate carcinoma stop_gained 0.6198% (3/484) 1 entry
ENSG00000080824 basal cell carcinoma missense_variant 1.724% (1/58) 1 entry
ENSG00000080824 squamous cell lung carcinoma sequence_alteration 0.8485% (7/825) 1 entry
ENSG00000080824 large cell lung carcinoma missense_variant 5.556% (1/18) 1 entry
ENSG00000080824 T-cell acute lymphoblastic leukemia sequence_alteration 0.2632% (1/380) 1 entry
ENSG00000080824 gastric adenocarcinoma sequence_alteration 1.178% (8/679) 1 entry
ENSG00000080824 clear cell renal carcinoma sequence_alteration 0.6074% (8/1317) 1 entry
ENSG00000080824 chromophobe renal cell carcinoma missense_variant 0.8772% (1/114) 1 entry
ENSG00000080824 cecum adenocarcinoma missense_variant 0.7634% (1/131) 1 entry
ENSG00000080824 skin melanoma sequence_alteration 0.5171% (5/967) 1 entry
ENSG00000080824 Ampulla of Vater Carcinoma missense_variant 1.176% (1/85) 1 entry
ENSG00000080824 rectal adenocarcinoma stop_gained 1.81% (4/221) 1 entry
ENSG00000080824 Thyroid Gland Undifferentiated (Anaplastic) Carcinoma missense_variant 0.5848% (1/171) 1 entry
ENSG00000080824 gastric intestinal type adenocarcinoma conservative_inframe_deletion 5.882% (5/85) 1 entry
ENSG00000080824 prostate carcinoma sequence_alteration 0.6198% (3/484) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000080824 MESO 0.0047 high
ENSG00000080824 UVM 0.0029 high
ENSG00000080824 PAAD 0.03 high
ENSG00000080824 LGG 0.043 high
ENSG00000080824 HNSC 0.0013 high
ENSG00000080824 KIRP 0.0051 high
ENSG00000080824 LUAD 0.0032 high
ENSG00000080824 BRCA 0.00053 high
ENSG00000080824 ESCA 0.041 high
ENSG00000080824 OV 0.011 low
ENSG00000080824 DLBC 0.0096 low
ENSG00000080824 KIRC 0.00041 low
ENSG00000080824 PRAD 0.034 high
ENSG00000080824 BLCA 0.031 high
ENSG00000080824 LAML 0.036 high
ENSG00000080824 SKCM 0.0061 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000080824 CHOL Del 1.999344 0.312766 0.657093 0.555556
ENSG00000080824 LUAD Del 1.341084 0.060007 0.312422 0.284884
ENSG00000080824 LGG Del 5.500398 0.078297 0.532212 0.210526
ENSG00000080824 CESC Del 2.310728 0.095787 0.476045 0.169492
ENSG00000080824 GBM Del 1.505792 0.062107 0.584964 0.279029
ENSG00000080824 HNSC Del 0.773722 0.055170 0.458005 0.139847
ENSG00000080824 LIHC Del 3.616552 0.106217 0.511373 0.356757
ENSG00000080824 BLCA Del 1.668020 0.093405 0.388119 0.301471
ENSG00000080824 BRCA Del 1.646533 0.071876 0.400934 0.285185
ENSG00000080824 STAD Del 2.533983 0.084943 0.350612 0.299320