Ensembl ID ENSG00000080603 Gene ID 10847 Accession 16974
Gene Symbol SRCAP Alias EAF1;FLHS;SWR1;DOMO1;DEHMBA Full Name Snf2 related CREBBP activator protein
Position 16 : 30698209 - 30741409 Length 43201 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]

ENSG00000080603 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000080603 0.35 6.69e-16 BRCA
ENSG00000080603 0.94 1.99e-26 KICH
ENSG00000080603 1.19 4.03e-31 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000080603 prostate cancer 20432434
ENSG00000080603 prostate tumor 20841388
ENSG00000080603 prostate cancer 24398858
ENSG00000080603 cancer 26796307
ENSG00000080603 tumor 28642609
ENSG00000080603 liver tumor 29925408
ENSG00000080603 cancer 31015463
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000080603 SARC 0.033 low
ENSG00000080603 CHOL 0.021 low
ENSG00000080603 UVM 0.036 low
ENSG00000080603 PAAD 0.013 high
ENSG00000080603 UCEC 0.0076 low
ENSG00000080603 ACC 0.012 low
ENSG00000080603 LUSC 0.01 high
ENSG00000080603 READ 0.017 low
ENSG00000080603 PCPG 0.0033 low
ENSG00000080603 THYM 0.021 low
ENSG00000080603 BRCA 0.037 high
ENSG00000080603 ESCA 0.0035 low
ENSG00000080603 OV 0.039 high
ENSG00000080603 TGCT 0.048 low
ENSG00000080603 LAML 0.039 high
ENSG00000080603 SKCM 0.00036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000080603 READ Amp 0.884377 0.134262 0.637183 0.284848
ENSG00000080603 COAD Amp 1.268480 0.079204 0.467406 0.277162
ENSG00000080603 UCS Amp 1.791223 0.662996 0.875468 0.357143
ENSG00000080603 UCEC Amp 1.731197 0.127560 0.677722 0.116883