Ensembl ID ENSG00000080503 Gene ID 6595 Accession 11098
Gene Symbol SMARCA2 Alias BIS;BRM;SNF2;SWI2;hBRM;NCBRS;Sth1p;BAF190;SNF2L2;SNF2LA;hSNF2a Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Position 9 : 1980290 - 2193624 Length 213335 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]

ENSG00000080503 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000080503 -0.9 7.18e-56 KIRC
ENSG00000080503 -0.6 1.41e-33 BRCA
ENSG00000080503 -0.6 7.37e-11 COAD
ENSG00000080503 -1.0 1.22e-21 KIRP
ENSG00000080503 -0.8 9.88e-12 LIHC
ENSG00000080503 -1.4 1.70e-21 UCEC
ENSG00000080503 -0.9 3.42e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000080503 tumour 10319872
ENSG00000080503 cancer 11274403
ENSG00000080503 cancer 11338758
ENSG00000080503 cancer 11471830
ENSG00000080503 tumor 11850839
ENSG00000080503 tumor 12149641
ENSG00000080503 lung cancers 12566296
ENSG00000080503 Cancer 12783373
ENSG00000080503 tumor 14508105
ENSG00000080503 cancer 14603256
ENSG00000080503 tumor 14619462
ENSG00000080503 cancer 14627127
ENSG00000080503 tumor 14990991
ENSG00000080503 cancer 15058795
ENSG00000080503 tumor 15160218
ENSG00000080503 non-small cell lung cancer 15240517
ENSG00000080503 cancer 1530341
ENSG00000080503 tumor 15485929
ENSG00000080503 cancer 15586241
ENSG00000080503 cancer 15622755
ENSG00000080503 primary cancers 15722796
ENSG00000080503 cancer 15751158
ENSG00000080503 Cancer 15804320
ENSG00000080503 tumor 15887247
ENSG00000080503 AML 15983063
ENSG00000080503 cancer 1599803
ENSG00000080503 tumor 16135788
ENSG00000080503 cancer 16158783
ENSG00000080503 tumor 16315899
ENSG00000080503 tumor 16452305
ENSG00000080503 tumor 16554097
ENSG00000080503 tumor 16824695
ENSG00000080503 tumor 1690346
ENSG00000080503 cancer 1697151
ENSG00000080503 prostate cancers 17075831
ENSG00000080503 cancer 1713048
ENSG00000080503 cancer 17546055
ENSG00000080503 Cancer 17570854
ENSG00000080503 cancers 1786197
ENSG00000080503 tumor 18508913
ENSG00000080503 esophageal cancer 1877817
ENSG00000080503 non-melanoma skin cancers 18923443
ENSG00000080503 liver cancer 1908665
ENSG00000080503 breast cancer 19183483
ENSG00000080503 cancer 1944195
ENSG00000080503 tumor 19488910
ENSG00000080503 tumours 19602054
ENSG00000080503 cancer 19784067
ENSG00000080503 malignant brain tumors 1992912
ENSG00000080503 breast tumors 20333683
ENSG00000080503 prostatic cancer 21092585
ENSG00000080503 tumor 21478905
ENSG00000080503 cancer 21478907
ENSG00000080503 cancer 21520050
ENSG00000080503 cancer 21534871
ENSG00000080503 tumours 21564052
ENSG00000080503 tumor 21811517
ENSG00000080503 cancer 2186383
ENSG00000080503 skin cancers 22123419
ENSG00000080503 tumors 22363625
ENSG00000080503 malignant rhabdoid tumors 22467207
ENSG00000080503 cancer 22942713
ENSG00000080503 tumor 23010866
ENSG00000080503 cancer 23045253
ENSG00000080503 tumours 23088494
ENSG00000080503 Lung cancer 23163725
ENSG00000080503 tumor 23229642
ENSG00000080503 tumor 2324583
ENSG00000080503 liver cancer 23267895
ENSG00000080503 GBM 23276717
ENSG00000080503 tumors 23322154
ENSG00000080503 tumor 23349796
ENSG00000080503 tumor 23359823
ENSG00000080503 tumor 2337372
ENSG00000080503 tumour 23478234
ENSG00000080503 tumor 23524580
ENSG00000080503 cancer 23533649
ENSG00000080503 cancer 23565070
ENSG00000080503 prostate cancer 23668334
ENSG00000080503 cancer 23872584
ENSG00000080503 tumor 2389941
ENSG00000080503 cancer 23936361
ENSG00000080503 cancer 2410519
ENSG00000080503 cancer 2415550
ENSG00000080503 tumors 24212667
ENSG00000080503 tumor 24231704
ENSG00000080503 cancer 24360954
ENSG00000080503 cancers 24421395
ENSG00000080503 tumours 24471421
ENSG00000080503 cancers 24519853
ENSG00000080503 cancers 24520176
ENSG00000080503 tumor 24522270
ENSG00000080503 cancer 2454612
ENSG00000080503 Tumor 24622842
ENSG00000080503 tumor 24817979
ENSG00000080503 cancer 24876151
ENSG00000080503 tumor 24913006
ENSG00000080503 cancer 24997128
ENSG00000080503 tumors 25026375
ENSG00000080503 rhabdoid tumor 25200863
ENSG00000080503 tumours 25254962
ENSG00000080503 tumors 25391308
ENSG00000080503 vulvar cancer 2543316
ENSG00000080503 cancer 25462860
ENSG00000080503 cancers 25484574
ENSG00000080503 malignant rhabdoid tumours 25496315
ENSG00000080503 tumor 25544751
ENSG00000080503 tumors 25774356
ENSG00000080503 breast cancers 25808524
ENSG00000080503 tumor 25904594
ENSG00000080503 cancer 26059320
ENSG00000080503 tumors 26097869
ENSG00000080503 tumors 26110843
ENSG00000080503 Cancers 26139243
ENSG00000080503 cancer 26233959
ENSG00000080503 tumour 26356327
ENSG00000080503 cancers 26359351
ENSG00000080503 cancer 26396593
ENSG00000080503 tumors 26551623
ENSG00000080503 tumors 26564006
ENSG00000080503 renal cancer 2658819
ENSG00000080503 tumors 26646792
ENSG00000080503 tumor 26702435
ENSG00000080503 tumors 26743474
ENSG00000080503 small cell Lung cancer 26796307
ENSG00000080503 cancers 26942101
ENSG00000080503 cancer 2699034
ENSG00000080503 tumor 27029062
ENSG00000080503 tumor 27188282
ENSG00000080503 intestinal cancer 2730024
ENSG00000080503 tumor 2730029
ENSG00000080503 cancer 27413115
ENSG00000080503 tumor 27486753
ENSG00000080503 pancreatic cancer 27487558
ENSG00000080503 cancers 27556043
ENSG00000080503 cancer 27617704
ENSG00000080503 tumors 27764136
ENSG00000080503 Non-Small Cell Lung Cancer 27827316
ENSG00000080503 tumor 2782888
ENSG00000080503 tumour 27905400
ENSG00000080503 cancer 27911230
ENSG00000080503 pancreatic cancer 27999365
ENSG00000080503 non-small cell lung cancer 28038711
ENSG00000080503 tumour 28070921
ENSG00000080503 tumors 28105457
ENSG00000080503 cancer 28105458
ENSG00000080503 tumor 28176137
ENSG00000080503 tumors 28177947
ENSG00000080503 cancer 28212646
ENSG00000080503 tumor 28232072
ENSG00000080503 ovarian cancers 28292935
ENSG00000080503 breast cancer 28421159
ENSG00000080503 cancer 28427211
ENSG00000080503 Tumor 28445125
ENSG00000080503 tumors 28521512
ENSG00000080503 tumors 28555282
ENSG00000080503 cancer 28571677
ENSG00000080503 tumor 28601660
ENSG00000080503 pancreatic cancer 28602977
ENSG00000080503 tumors 28643792
ENSG00000080503 tumors 28697345
ENSG00000080503 cancer 28811898
ENSG00000080503 tumors 28844694
ENSG00000080503 tumor 28870942
ENSG00000080503 pancreatic cancers 28892201
ENSG00000080503 tumors 29087303
ENSG00000080503 cancer 29273066
ENSG00000080503 cancer 29391527
ENSG00000080503 ovarian cancer 29440177
ENSG00000080503 tumor 29482773
ENSG00000080503 pancreatic cancers 29515757
ENSG00000080503 cancer 2952067
ENSG00000080503 gastric cancer 2968070
ENSG00000080503 cancers 29795359
ENSG00000080503 colorectal cancer 29894502
ENSG00000080503 epithelial ovarian cancer 30127991
ENSG00000080503 tumor 30178299
ENSG00000080503 prostate cancer 30278885
ENSG00000080503 cancers 30287812
ENSG00000080503 ovarian cancer 30297712
ENSG00000080503 Cancers 30339381
ENSG00000080503 tumor 3036718
ENSG00000080503 cancer 30382367
ENSG00000080503 lung cancer 30447346
ENSG00000080503 tumors 30451731
ENSG00000080503 Lung Cancer 30478150
ENSG00000080503 cancers 30527810
ENSG00000080503 tumor 30667054
ENSG00000080503 lung cancer 3067072
ENSG00000080503 tumors 30718506
ENSG00000080503 pancreatic cancer 30745850
ENSG00000080503 pancreatic cancer 30790683
ENSG00000080503 lung cancer 30877105
ENSG00000080503 tumors 30897306
ENSG00000080503 tumours 30898143
ENSG00000080503 cancer 30910006
ENSG00000080503 breast cancer 30946989
ENSG00000080503 primary liver cancer 3099651
ENSG00000080503 AML 31091680
ENSG00000080503 cancer 31178587
ENSG00000080503 pancreatic cancer 31238554
ENSG00000080503 tumors 31273213
ENSG00000080503 tumors 31288309
ENSG00000080503 cancers 31355511
ENSG00000080503 cancers 31406271
ENSG00000080503 cancers 31427792
ENSG00000080503 tumor 31448657
ENSG00000080503 cancers 31602276
ENSG00000080503 tumour 31722744
ENSG00000080503 tumor 3180149
ENSG00000080503 tumor 31909846
ENSG00000080503 tumor 31988001
ENSG00000080503 cancer 3260467
ENSG00000080503 cancer 3382231
ENSG00000080503 cancer 3382233
ENSG00000080503 cancer 3408253
ENSG00000080503 tumor 3488023
ENSG00000080503 tumor 3488024
ENSG00000080503 cancer 3494429
ENSG00000080503 cancer 3538633
ENSG00000080503 tumor 3729450
ENSG00000080503 breast cancer 3873910
ENSG00000080503 tumor 3994067
ENSG00000080503 cancer 6188871
ENSG00000080503 cancer 6202795
ENSG00000080503 tumor 6235447
ENSG00000080503 tumor 7574777
ENSG00000080503 tumor 7807182
ENSG00000080503 pancreatic cancer 7838109
ENSG00000080503 cancer 7855624
ENSG00000080503 cancer 8103128
ENSG00000080503 tumors 8239902
ENSG00000080503 tumour 8267386
ENSG00000080503 tumor 8476212
ENSG00000080503 cancer 8854802
ENSG00000080503 metastatic tumors 8924352
ENSG00000080503 colorectal cancer 9382553
ENSG00000080503 lung cancer 9427781
ENSG00000080503 tumor 9586358
ENSG00000080503 lung cancer 9597487
ENSG00000080503 tumor 9829383
ENSG00000080503 cancer 9950100
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000080503 MESO 0.00035 low
ENSG00000080503 UVM 0.0027 high
ENSG00000080503 PAAD 0.0052 low
ENSG00000080503 THCA 5e-04 high
ENSG00000080503 LGG 0.00061 low
ENSG00000080503 HNSC 0.0079 low
ENSG00000080503 READ 0.02 low
ENSG00000080503 KIRP 0.0093 low
ENSG00000080503 KICH 0.039 high
ENSG00000080503 LUAD 0.036 low
ENSG00000080503 THYM 0.012 high
ENSG00000080503 BRCA 0.029 high
ENSG00000080503 COAD 0.044 high
ENSG00000080503 ESCA 0.0028 low
ENSG00000080503 OV 0.047 high
ENSG00000080503 PRAD 0.037 high
ENSG00000080503 LAML 0.025 high
ENSG00000080503 SKCM 0.006 low
ENSG00000080503 CESC 0.026 low
ENSG00000080503 LIHC 0.047 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000080503 LUSC Del 11.275166 0.158400 0.437938 0.656687
ENSG00000080503 LUAD Del 8.993277 0.120015 0.386129 0.529070
ENSG00000080503 LGG Del 11.148191 0.110375 0.542631 0.288499
ENSG00000080503 CESC Amp 1.297311 0.152203 0.690428 0.203390
ENSG00000080503 UCS Del 1.572094 0.278396 0.512965 0.607143
ENSG00000080503 SARC Del 4.292402 0.204313 0.564514 0.385214
ENSG00000080503 GBM Del 18.215172 0.169434 0.677952 0.396880
ENSG00000080503 PAAD Del 1.597036 0.063547 0.376727 0.456522
ENSG00000080503 ESCA Del 2.749164 0.151806 0.469101 0.586957
ENSG00000080503 SKCM Del 4.665309 0.118590 0.568875 0.673025
ENSG00000080503 HNSC Amp 3.270535 0.173014 0.648232 0.233716
ENSG00000080503 HNSC Del 4.376284 0.087732 0.457885 0.413793
ENSG00000080503 TGCT Del 4.134723 0.126309 0.406819 0.466667
ENSG00000080503 BLCA Del 2.101202 0.099774 0.499828 0.433824
ENSG00000080503 BRCA Del 1.400289 0.069871 0.440932 0.300926
ENSG00000080503 STAD Del 5.778952 0.114893 0.433901 0.399093
ENSG00000080503 OV Del 2.724244 0.215034 0.630965 0.450777