Ensembl ID ENSG00000079785 Gene ID 1653 Accession 2734
Gene Symbol DDX1 Alias DBP-RB;UKVH5d Full Name DEAD-box helicase 1
Position 2 : 15591178 - 15634346 Length 43169 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that acts as an ATP-dependent RNA helicase that has been found to promote coronaviruses replication. [provided by RefSeq, Aug 2021]

ENSG00000079785 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000079785 DDX1 -0.3 5.85e-21 KIRC
ENSG00000079785 DDX1 0.58 1.57e-13 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000079785 DDX1 tumors 10319407
ENSG00000079785 DDX1 tumors 10935481
ENSG00000079785 DDX1 tumors 15226335
ENSG00000079785 DDX1 tumor 17028906
ENSG00000079785 DDX1 tumor 17044047
ENSG00000079785 DDX1 tumours 17611020
ENSG00000079785 DDX1 childhood tumors 17927523
ENSG00000079785 DDX1 tumors 18710941
ENSG00000079785 DDX1 GBM 19139420
ENSG00000079785 DDX1 tumors 19398953
ENSG00000079785 DDX1 tumours 19615087
ENSG00000079785 DDX1 breast cancer 20499159
ENSG00000079785 DDX1 breast cancer 20694745
ENSG00000079785 DDX1 tumor 21154590
ENSG00000079785 DDX1 breast cancer 21761397
ENSG00000079785 DDX1 tumors 22085494
ENSG00000079785 DDX1 breast cancer 23216862
ENSG00000079785 DDX1 ovarian tumor 25176654
ENSG00000079785 DDX1 tumor 25690890
ENSG00000079785 DDX1 cancer 25909345
ENSG00000079785 DDX1 ovarian cancer 26308063
ENSG00000079785 DDX1 tumour 26323305
ENSG00000079785 DDX1 tumor 26713367
ENSG00000079785 DDX1 colorectal cancer 28040436
ENSG00000079785 DDX1 colorectal cancer 29869821
ENSG00000079785 DDX1 Wilms' tumor 31057612
ENSG00000079785 DDX1 tumours 8622876
ENSG00000079785 DDX1 tumors 8834177
ENSG00000079785 DDX1 tumors 8875996
ENSG00000079785 DDX1 tumours 9516849
ENSG00000079785 DDX1 tumors 9694872
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000079785 DDX1 MESO 0.027 high
ENSG00000079785 DDX1 SARC 0.049 high
ENSG00000079785 DDX1 UVM 0.027 high
ENSG00000079785 DDX1 UCEC 0.0049 high
ENSG00000079785 DDX1 ACC 0.00029 high
ENSG00000079785 DDX1 LGG 0.011 low
ENSG00000079785 DDX1 LUSC 0.0029 low
ENSG00000079785 DDX1 HNSC 0.0018 high
ENSG00000079785 DDX1 KICH 0.014 high
ENSG00000079785 DDX1 OV 0.0058 low
ENSG00000079785 DDX1 BLCA 0.0027 high
ENSG00000079785 DDX1 GBM 0.0055 low
ENSG00000079785 DDX1 SKCM 0.0017 low
ENSG00000079785 DDX1 CESC 0.01 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000079785 DDX1 GBM Amp 3.763392 0.117257 0.876379 0.077990
ENSG00000079785 DDX1 LIHC Amp 1.082611 0.123315 0.531693 0.167568
ENSG00000079785 DDX1 TGCT Amp 1.710327 0.163905 0.451276 0.393333
ENSG00000079785 DDX1 UCEC Amp 2.255653 0.138087 0.612049 0.224490