Ensembl ID
ENSG00000079134
Gene ID
9984
Accession
19070
Gene Symbol
THOC1
Alias
P84;HPR1;P84N5;DFNA86
Full Name
THO complex subunit 1
Position
18 : 214520 - 268050
Length
53531 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
Predicted to enable DNA binding activity and RNA binding activity. Involved in several processes, including negative regulation of DNA damage checkpoint; regulation of nucleobase-containing compound metabolic process; and viral mRNA export from host cell nucleus. Located in cytoplasm and nuclear speck. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000079134 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000079134
THOC1
0.74
8.02e-27
KIRC
ENSG00000079134
THOC1
0.71
9.11e-16
LUSC
ENSG00000079134
THOC1
0.64
1.02e-15
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000079134
THOC1
tumor
10840029
ENSG00000079134
THOC1
cancer
11593432
ENSG00000079134
THOC1
tumor
12136427
ENSG00000079134
THOC1
tumor
15358532
ENSG00000079134
THOC1
breast cancer
15833825
ENSG00000079134
THOC1
tumor
21329510
ENSG00000079134
THOC1
ovarian cancer
22952718
ENSG00000079134
THOC1
prostate cancer
25296641
ENSG00000079134
THOC1
tumor
27035147
ENSG00000079134
THOC1
tumor
27679854
ENSG00000079134
THOC1
breast cancer
31889940
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000079134
THOC1
MESO
0.002
high
show
ENSG00000079134
THOC1
UVM
0.031
high
show
ENSG00000079134
THOC1
PAAD
0.039
low
show
ENSG00000079134
THOC1
UCEC
0.0019
high
show
ENSG00000079134
THOC1
ACC
0.0024
high
show
ENSG00000079134
THOC1
LGG
0.0027
high
show
ENSG00000079134
THOC1
LUSC
0.00098
low
show
ENSG00000079134
THOC1
KIRP
0.049
low
show
ENSG00000079134
THOC1
KICH
0.016
high
show
ENSG00000079134
THOC1
LUAD
0.0011
low
show
ENSG00000079134
THOC1
THYM
0.0046
low
show
ENSG00000079134
THOC1
BRCA
0.00031
low
show
ENSG00000079134
THOC1
COAD
0.049
high
show
ENSG00000079134
THOC1
UCS
0.0084
high
show
ENSG00000079134
THOC1
ESCA
0.044
high
show
ENSG00000079134
THOC1
PRAD
0.018
high
show
ENSG00000079134
THOC1
BLCA
0.00041
low
show
ENSG00000079134
THOC1
LAML
0.00083
low
show
ENSG00000079134
THOC1
GBM
0.04
high
show
ENSG00000079134
THOC1
SKCM
0.0015
low
show
ENSG00000079134
THOC1
CESC
0.0034
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
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