Ensembl ID
ENSG00000078269
Gene ID
8871
Accession
11504
Gene Symbol
SYNJ2
Alias
INPP5H
Full Name
synaptojanin 2
Position
6 : 157981863 - 158099176
Length
117314 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Canonical_RBPs
Summary
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
ENSG00000078269 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000078269
1.08
2.57e-28
LUSC
ENSG00000078269
1.51
8.90e-52
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000078269
malignant tumors
15548694
ENSG00000078269
prostate cancer
16102578
ENSG00000078269
tumor
23076136
ENSG00000078269
breast cancer
25605973
ENSG00000078269
colorectal cancer
26616230
ENSG00000078269
tumor
29163781
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000078269
MESO
0.00024
high
show
ENSG00000078269
STAD
0.018
low
show
ENSG00000078269
PAAD
0.0011
low
show
ENSG00000078269
UCEC
0.016
high
show
ENSG00000078269
LGG
0.0046
high
show
ENSG00000078269
LUSC
0.014
high
show
ENSG00000078269
READ
0.029
low
show
ENSG00000078269
KIRP
0.00091
high
show
ENSG00000078269
KICH
0.00014
high
show
ENSG00000078269
LUAD
0.012
high
show
ENSG00000078269
THYM
0.00021
low
show
ENSG00000078269
ESCA
0.0013
low
show
ENSG00000078269
OV
0.0052
high
show
ENSG00000078269
DLBC
0.036
high
show
ENSG00000078269
TGCT
0.033
high
show
ENSG00000078269
LAML
0.033
high
show
ENSG00000078269
GBM
0.016
high
show
ENSG00000078269
CESC
0.02
high
show
ENSG00000078269
LIHC
0.019
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000078269
LUAD
Del
2.110708
0.068400
0.375212
0.507752
ENSG00000078269
LGG
Del
1.210919
0.044741
0.574253
0.155945
ENSG00000078269
CESC
Del
1.566858
0.084043
0.474932
0.325424
ENSG00000078269
GBM
Del
9.202744
0.120461
0.563629
0.282496
ENSG00000078269
SKCM
Del
5.396694
0.126260
0.559453
0.602180
ENSG00000078269
LIHC
Del
4.320949
0.114117
0.606892
0.375676
ENSG00000078269
BLCA
Del
0.753441
0.077749
0.375894
0.458333
ENSG00000078269
BRCA
Del
11.124029
0.119092
0.484276
0.333333
ENSG00000078269
STAD
Del
1.258035
0.068740
0.358638
0.208617
ENSG00000078269
MESO
Del
1.211708
0.145598
0.532586
0.413793
ENSG00000078269
KIRC
Del
6.540876
0.053107
0.462371
0.285985
ENSG00000078269
UVM
Del
1.628635
0.094732
0.833766
0.312500
ENSG00000078269
OV
Del
32.012608
0.462791
0.662003
0.642487
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.