Ensembl ID ENSG00000076928 Gene ID 9138 Accession 681
Gene Symbol ARHGEF1 Alias LSC;GEF1;IMD62;LBCL2;SUB1.5;P115-RHOGEF Full Name Rho guanine nucleotide exchange factor 1
Position 19 : 41883184 - 41930150 Length 46967 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

ENSG00000076928 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000076928 1.17 2.43e-52 KIRC
ENSG00000076928 0.64 3.29e-18 HNSC
ENSG00000076928 0.49 8.47e-14 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000076928 breast cancer 12748184
ENSG00000076928 tumors 15548366
ENSG00000076928 prostate cancer 20734387
ENSG00000076928 tumor 21634119
ENSG00000076928 DLBCL 25274307
ENSG00000076928 breast cancer 25840418
ENSG00000076928 tumor 26258642
ENSG00000076928 DLBCL 26654227
ENSG00000076928 tumor 26911374
ENSG00000076928 metastatic prostate cancer 27206800
ENSG00000076928 tumor 27355516
ENSG00000076928 cancer 27765040
ENSG00000076928 breast cancer 29190905
ENSG00000076928 breast-cancer 31667337
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000076928 MESO 0.023 high
ENSG00000076928 PAAD 0.022 low
ENSG00000076928 UCEC 0.00014 low
ENSG00000076928 LUSC 0.02 high
ENSG00000076928 HNSC 0.007 low
ENSG00000076928 KIRP 0.011 high
ENSG00000076928 KICH 0.0021 low
ENSG00000076928 PCPG 0.031 low
ENSG00000076928 THYM 0.00013 low
ENSG00000076928 BRCA 0.00028 low
ENSG00000076928 COAD 0.00095 high
ENSG00000076928 UCS 0.0057 high
ENSG00000076928 ESCA 0.024 low
ENSG00000076928 OV 0.014 high
ENSG00000076928 PRAD 0.018 high
ENSG00000076928 BLCA 0.0077 low
ENSG00000076928 LAML 0.00032 high
ENSG00000076928 GBM 0.042 high
ENSG00000076928 SKCM 0.031 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000076928 LUSC Del 1.191801 0.073041 0.366590 0.233533
ENSG00000076928 LGG Del 7.557632 0.090748 0.663367 0.469786
ENSG00000076928 GBM Del 5.382988 0.095506 0.537082 0.119584
ENSG00000076928 OV Del 6.554531 0.264772 0.587508 0.417962