Ensembl ID
ENSG00000075856
Gene ID
9733
Accession
16860
Gene Symbol
SART3
Alias
P100;p110;DSAP1;TIP110;p110(nrb);RP11-13G14
Full Name
spliceosome associated factor 3, U4/U6 recycling protein
Position
12 : 108522214 - 108561400
Length
39187 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]
ENSG00000075856 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000075856
SART3
0.39
2.13e-14
COAD
ENSG00000075856
SART3
0.44
5.89e-15
LUSC
ENSG00000075856
SART3
0.42
4.73e-12
STAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000075856
SART3
gastric cancers
10760694
ENSG00000075856
SART3
Tumor
10761712
ENSG00000075856
SART3
brain tumors
11001544
ENSG00000075856
SART3
tumor
11058882
ENSG00000075856
SART3
tumor
11061933
ENSG00000075856
SART3
gynecologic cancers
11092984
ENSG00000075856
SART3
breast cancer
11286471
ENSG00000075856
SART3
tumors
11398844
ENSG00000075856
SART3
oral cancers
11402621
ENSG00000075856
SART3
tumor
11477570
ENSG00000075856
SART3
colorectal cancer
11751487
ENSG00000075856
SART3
tumor
11920522
ENSG00000075856
SART3
cancers
12458792
ENSG00000075856
SART3
tumor
15010873
ENSG00000075856
SART3
tumor
16188028
ENSG00000075856
SART3
tumor
16489090
ENSG00000075856
SART3
prostate cancer
16937115
ENSG00000075856
SART3
prostate cancer
19148489
ENSG00000075856
SART3
cancer
21447833
ENSG00000075856
SART3
cancer
22132941
ENSG00000075856
SART3
cancers
23822148
ENSG00000075856
SART3
tumor
24984263
ENSG00000075856
SART3
tumor
25013909
ENSG00000075856
SART3
tumor
25819159
ENSG00000075856
SART3
Cancer
25939381
ENSG00000075856
SART3
tumors
26203351
ENSG00000075856
SART3
colorectal cancer
26343847
ENSG00000075856
SART3
GBM
26881967
ENSG00000075856
SART3
cancer
26896687
ENSG00000075856
SART3
breast tumor
28096337
ENSG00000075856
SART3
tumor
28114424
ENSG00000075856
SART3
cancer
28584285
ENSG00000075856
SART3
tumor
28622427
ENSG00000075856
SART3
Tumor
28835717
ENSG00000075856
SART3
oral cancer
29443735
ENSG00000075856
SART3
tumor
29590477
ENSG00000075856
SART3
tumor
29938870
ENSG00000075856
SART3
lung cancer
31619517
ENSG00000075856
SART3
cancer
31956895
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000075856
SART3
MESO
0.034
high
show
ENSG00000075856
SART3
SARC
0.033
high
show
ENSG00000075856
SART3
STAD
0.0016
low
show
ENSG00000075856
SART3
UVM
0.045
high
show
ENSG00000075856
SART3
PAAD
0.019
low
show
ENSG00000075856
SART3
ACC
0.023
high
show
ENSG00000075856
SART3
LGG
0.028
low
show
ENSG00000075856
SART3
HNSC
0.017
low
show
ENSG00000075856
SART3
THYM
0.0088
low
show
ENSG00000075856
SART3
COAD
0.026
high
show
ENSG00000075856
SART3
UCS
0.024
low
show
ENSG00000075856
SART3
KIRC
0.018
low
show
ENSG00000075856
SART3
LAML
0.0059
high
show
ENSG00000075856
SART3
GBM
0.022
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000075856
SART3
CHOL
Del
0.848275
0.219537
0.589045
0.222222
ENSG00000075856
SART3
PAAD
Del
1.596230
0.063547
0.352967
0.228261
ENSG00000075856
SART3
SKCM
Del
1.519854
0.079650
0.435299
0.242507
ENSG00000075856
SART3
BRCA
Del
2.146667
0.075685
0.383380
0.184259
ENSG00000075856
SART3
UCEC
Del
0.720455
0.047805
0.382150
0.105751
ENSG00000075856
SART3
OV
Del
2.383488
0.209425
0.554287
0.321244
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