Ensembl ID ENSG00000075856 Gene ID 9733 Accession 16860
Gene Symbol SART3 Alias P100;p110;DSAP1;TIP110;p110(nrb);RP11-13G14 Full Name spliceosome associated factor 3, U4/U6 recycling protein
Position 12 : 108522214 - 108561400 Length 39187 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]

ENSG00000075856 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000075856 SART3 0.39 2.13e-14 COAD
ENSG00000075856 SART3 0.44 5.89e-15 LUSC
ENSG00000075856 SART3 0.42 4.73e-12 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000075856 SART3 gastric cancers 10760694
ENSG00000075856 SART3 Tumor 10761712
ENSG00000075856 SART3 brain tumors 11001544
ENSG00000075856 SART3 tumor 11058882
ENSG00000075856 SART3 tumor 11061933
ENSG00000075856 SART3 gynecologic cancers 11092984
ENSG00000075856 SART3 breast cancer 11286471
ENSG00000075856 SART3 tumors 11398844
ENSG00000075856 SART3 oral cancers 11402621
ENSG00000075856 SART3 tumor 11477570
ENSG00000075856 SART3 colorectal cancer 11751487
ENSG00000075856 SART3 tumor 11920522
ENSG00000075856 SART3 cancers 12458792
ENSG00000075856 SART3 tumor 15010873
ENSG00000075856 SART3 tumor 16188028
ENSG00000075856 SART3 tumor 16489090
ENSG00000075856 SART3 prostate cancer 16937115
ENSG00000075856 SART3 prostate cancer 19148489
ENSG00000075856 SART3 cancer 21447833
ENSG00000075856 SART3 cancer 22132941
ENSG00000075856 SART3 cancers 23822148
ENSG00000075856 SART3 tumor 24984263
ENSG00000075856 SART3 tumor 25013909
ENSG00000075856 SART3 tumor 25819159
ENSG00000075856 SART3 Cancer 25939381
ENSG00000075856 SART3 tumors 26203351
ENSG00000075856 SART3 colorectal cancer 26343847
ENSG00000075856 SART3 GBM 26881967
ENSG00000075856 SART3 cancer 26896687
ENSG00000075856 SART3 breast tumor 28096337
ENSG00000075856 SART3 tumor 28114424
ENSG00000075856 SART3 cancer 28584285
ENSG00000075856 SART3 tumor 28622427
ENSG00000075856 SART3 Tumor 28835717
ENSG00000075856 SART3 oral cancer 29443735
ENSG00000075856 SART3 tumor 29590477
ENSG00000075856 SART3 tumor 29938870
ENSG00000075856 SART3 lung cancer 31619517
ENSG00000075856 SART3 cancer 31956895
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000075856 SART3 MESO 0.034 high
ENSG00000075856 SART3 SARC 0.033 high
ENSG00000075856 SART3 STAD 0.0016 low
ENSG00000075856 SART3 UVM 0.045 high
ENSG00000075856 SART3 PAAD 0.019 low
ENSG00000075856 SART3 ACC 0.023 high
ENSG00000075856 SART3 LGG 0.028 low
ENSG00000075856 SART3 HNSC 0.017 low
ENSG00000075856 SART3 THYM 0.0088 low
ENSG00000075856 SART3 COAD 0.026 high
ENSG00000075856 SART3 UCS 0.024 low
ENSG00000075856 SART3 KIRC 0.018 low
ENSG00000075856 SART3 LAML 0.0059 high
ENSG00000075856 SART3 GBM 0.022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000075856 SART3 CHOL Del 0.848275 0.219537 0.589045 0.222222
ENSG00000075856 SART3 PAAD Del 1.596230 0.063547 0.352967 0.228261
ENSG00000075856 SART3 SKCM Del 1.519854 0.079650 0.435299 0.242507
ENSG00000075856 SART3 BRCA Del 2.146667 0.075685 0.383380 0.184259
ENSG00000075856 SART3 UCEC Del 0.720455 0.047805 0.382150 0.105751
ENSG00000075856 SART3 OV Del 2.383488 0.209425 0.554287 0.321244