Ensembl ID ENSG00000075785 Gene ID 7879 Accession 9788
Gene Symbol RAB7A Alias RAB7;CMT2B;PRO2706 Full Name RAB7A, member RAS oncogene family
Position 3 : 128693669 - 128825942 Length 132274 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]

ENSG00000075785 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000075785 cancer 22922681
ENSG00000075785 Tumor 23933150
ENSG00000075785 tumor 24981740
ENSG00000075785 tumor 25180605
ENSG00000075785 tumor 26008978
ENSG00000075785 cancer 27136326
ENSG00000075785 cancer 28545132
ENSG00000075785 cancer 29382080
ENSG00000075785 breast cancer 29769411
ENSG00000075785 tumor 29868251
ENSG00000075785 cancer 30626032
ENSG00000075785 colon cancer 30765602
ENSG00000075785 Tumor 31374919
ENSG00000075785 tumor 31409279
ENSG00000075785 Triple-Negative Breast Cancer 31662325
ENSG00000075785 tumors 9428630
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000075785 UVM 1e-04 low
ENSG00000075785 PAAD 0.00062 high
ENSG00000075785 THCA 0.0025 low
ENSG00000075785 LGG 0.037 high
ENSG00000075785 HNSC 0.032 high
ENSG00000075785 KIRP 0.0085 high
ENSG00000075785 KICH 0.014 high
ENSG00000075785 LUAD 0.032 high
ENSG00000075785 PCPG 0.017 high
ENSG00000075785 BRCA 0.044 high
ENSG00000075785 COAD 0.0087 high
ENSG00000075785 KIRC 0.00092 low
ENSG00000075785 BLCA 0.0059 high
ENSG00000075785 LAML 0.017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000075785 GBM Del 1.154418 0.057791 0.493485 0.093588
ENSG00000075785 PCPG Del 0.861876 0.062152 0.630185 0.567901
ENSG00000075785 PRAD Amp 2.393465 0.068850 0.432586 0.148374