Ensembl ID ENSG00000075618 Gene ID 6624 Accession 11148
Gene Symbol FSCN1 Alias HSN;SNL;p55;FAN1 Full Name fascin actin-bundling protein 1
Position 7 : 5592816 - 5606655 Length 13840 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

ENSG00000075618 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000075618 1.55 5.02e-46 KIRC
ENSG00000075618 1.66 7.80e-34 HNSC
ENSG00000075618 1.57 7.91e-13 COAD
ENSG00000075618 2.60 4.00e-64 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000075618 tumor 10026156
ENSG00000075618 breast cancer 10970687
ENSG00000075618 breast cancer 11039904
ENSG00000075618 tumor 11169763
ENSG00000075618 ovarian tumors 11206843
ENSG00000075618 tumor 11391592
ENSG00000075618 tumours 11688968
ENSG00000075618 tumor 11795941
ENSG00000075618 Tumor 11796841
ENSG00000075618 tumour 11857023
ENSG00000075618 tumor 11914634
ENSG00000075618 breast cancer 11943599
ENSG00000075618 tumour 11990524
ENSG00000075618 tumor 12100631
ENSG00000075618 tumors 12109856
ENSG00000075618 cancers 12139639
ENSG00000075618 endometrial cancer 12365393
ENSG00000075618 tumor 12507891
ENSG00000075618 Wilms' tumor 12525565
ENSG00000075618 tumours 12592367
ENSG00000075618 tumour 12637246
ENSG00000075618 tumor 12676264
ENSG00000075618 tumor 12733148
ENSG00000075618 tumor 12960804
ENSG00000075618 pancreas cancer 13679454
ENSG00000075618 tumors 14568688
ENSG00000075618 tumour 14636259
ENSG00000075618 lung cancer 15073598
ENSG00000075618 tumor 15154661
ENSG00000075618 dendritic cell tumor 15467709
ENSG00000075618 tumors 15557788
ENSG00000075618 tumour 1558793
ENSG00000075618 mucinous tumors 15626919
ENSG00000075618 breast cancer 15671545
ENSG00000075618 tumor 15696124
ENSG00000075618 tumor 15806378
ENSG00000075618 tumor 15814639
ENSG00000075618 Tumor 15948122
ENSG00000075618 tumour 15970923
ENSG00000075618 tumours 16002322
ENSG00000075618 cancer 16077993
ENSG00000075618 tumors 16084942
ENSG00000075618 tumor 16185662
ENSG00000075618 tumors 16308158
ENSG00000075618 malignant tumor 16398226
ENSG00000075618 primary cancer 16492916
ENSG00000075618 tumour 16524962
ENSG00000075618 breast cancer 16533778
ENSG00000075618 Tumor 16564140
ENSG00000075618 tumors 16620052
ENSG00000075618 tumor 16620064
ENSG00000075618 tumors 16870459
ENSG00000075618 tumor 16872443
ENSG00000075618 metastatic tumor 16979727
ENSG00000075618 tumor 17021824
ENSG00000075618 tumor 17029629
ENSG00000075618 tumour 1704873
ENSG00000075618 tumor 17139983
ENSG00000075618 tumor 17187659
ENSG00000075618 cervical cancer 17192825
ENSG00000075618 tumour 1733440
ENSG00000075618 tumours 17375048
ENSG00000075618 colorectal cancer 17376711
ENSG00000075618 tumor 17404079
ENSG00000075618 tumor 17419223
ENSG00000075618 tumor 17473384
ENSG00000075618 tumor 17486683
ENSG00000075618 tumor 17499430
ENSG00000075618 tumor 17510372
ENSG00000075618 colon cancer 17638895
ENSG00000075618 tumour 1764363
ENSG00000075618 tumour 17650213
ENSG00000075618 tumor 17855511
ENSG00000075618 tumors 18281472
ENSG00000075618 glial tumors 18298442
ENSG00000075618 tumors 18343949
ENSG00000075618 tumor 18353580
ENSG00000075618 ovarian epithelial tumors 18498068
ENSG00000075618 Tumor 18575752
ENSG00000075618 tumors 18583236
ENSG00000075618 tumor 18587253
ENSG00000075618 tumor 18590537
ENSG00000075618 tumor 18608216
ENSG00000075618 tumour 1861682
ENSG00000075618 ovarian cancer 18630479
ENSG00000075618 tumor 18687388
ENSG00000075618 tumour 18716283
ENSG00000075618 cervical cancer 18717490
ENSG00000075618 Cancer 18751399
ENSG00000075618 tumor 18776588
ENSG00000075618 tumor 18851787
ENSG00000075618 tumour 18854838
ENSG00000075618 tumour 1892747
ENSG00000075618 tumor 1901889
ENSG00000075618 tumor 19061289
ENSG00000075618 tumor 19094485
ENSG00000075618 ovarian granulosa cell tumors 19115695
ENSG00000075618 tumour 19133007
ENSG00000075618 tumor 19170683
ENSG00000075618 serous tumors of ovary 19188814
ENSG00000075618 tumor 19207554
ENSG00000075618 prostate cancer 19228738
ENSG00000075618 Cancer 19245589
ENSG00000075618 cancer 19259612
ENSG00000075618 tumour 19340314
ENSG00000075618 oral cancer 19473443
ENSG00000075618 smooth muscle tumors 19483633
ENSG00000075618 cancers 19556073
ENSG00000075618 tumor 19574018
ENSG00000075618 cancers 19592575
ENSG00000075618 tumour 19694824
ENSG00000075618 tumour 19738613
ENSG00000075618 cancers 19741544
ENSG00000075618 gastric cancer 19818782
ENSG00000075618 tumours 19922708
ENSG00000075618 tumors 20064377
ENSG00000075618 cancer 20098684
ENSG00000075618 tumour 20131060
ENSG00000075618 cancer 20137952
ENSG00000075618 tumour 20160723
ENSG00000075618 tumors 20186299
ENSG00000075618 tumours 2021849
ENSG00000075618 tumor 20371278
ENSG00000075618 tumour 20393565
ENSG00000075618 colon cancer 20410808
ENSG00000075618 cancer 20502940
ENSG00000075618 tumor 20565981
ENSG00000075618 tumor 20596974
ENSG00000075618 cancer 20601080
ENSG00000075618 tumor 20701077
ENSG00000075618 tumors 20713986
ENSG00000075618 cancer 20714410
ENSG00000075618 breast cancer 20818426
ENSG00000075618 tumour 20819441
ENSG00000075618 bladder cancer 20843712
ENSG00000075618 colorectal cancer 20851411
ENSG00000075618 cervical cancer 20862378
ENSG00000075618 tumor 20888270
ENSG00000075618 malignant tumor 20949550
ENSG00000075618 tumour 20969772
ENSG00000075618 Tumor 21053535
ENSG00000075618 tumor 21195425
ENSG00000075618 cancer 21223690
ENSG00000075618 prostate cancer 21258769
ENSG00000075618 tumor 21300980
ENSG00000075618 cancer 21323792
ENSG00000075618 tumours 21345224
ENSG00000075618 Tumor 21351259
ENSG00000075618 tumor 21390241
ENSG00000075618 tumor 21393873
ENSG00000075618 tumor 21475911
ENSG00000075618 breast cancer 21491467
ENSG00000075618 tumor 21498718
ENSG00000075618 tumor 21562037
ENSG00000075618 cancer 21618240
ENSG00000075618 cancer 21685497
ENSG00000075618 breast cancer 21723890
ENSG00000075618 tumor 21764699
ENSG00000075618 tumour 21771028
ENSG00000075618 tumor 21789898
ENSG00000075618 tumor 21793333
ENSG00000075618 tumor 21859738
ENSG00000075618 cancer 21913182
ENSG00000075618 tumor 21914811
ENSG00000075618 breast cancer 21937440
ENSG00000075618 gastrointestinal stromal tumors 21948565
ENSG00000075618 cancer 21975551
ENSG00000075618 cancer 21980368
ENSG00000075618 Breast Cancer 22076152
ENSG00000075618 cancer 22102721
ENSG00000075618 pancreatic cancer 22110277
ENSG00000075618 tumour 22128198
ENSG00000075618 tumours 22236355
ENSG00000075618 tumor 22264292
ENSG00000075618 cancer 22269404
ENSG00000075618 tumor 22282584
ENSG00000075618 breast cancer 22292984
ENSG00000075618 tumor 22351250
ENSG00000075618 tumors 22427958
ENSG00000075618 tumors 22457808
ENSG00000075618 liver cancer 22495401
ENSG00000075618 cancer 22646265
ENSG00000075618 tumour 22784357
ENSG00000075618 tumor 22848263
ENSG00000075618 cancer 22883572
ENSG00000075618 tumor 22917928
ENSG00000075618 gastric cancers 22929309
ENSG00000075618 tumor 23030700
ENSG00000075618 cancer 23051736
ENSG00000075618 tumor 23152886
ENSG00000075618 gastrointestinal stromal tumor 23196799
ENSG00000075618 tumor 23209815
ENSG00000075618 tumor 23221510
ENSG00000075618 gastric cancer 23252866
ENSG00000075618 tumor 23264904
ENSG00000075618 cancer 23302167
ENSG00000075618 tumor 23360534
ENSG00000075618 tumour 23365595
ENSG00000075618 epithelial ovarian cancer 23393326
ENSG00000075618 tumor 23404256
ENSG00000075618 tumor 23442983
ENSG00000075618 cancer 23443037
ENSG00000075618 tumor 23489501
ENSG00000075618 tumor 23505378
ENSG00000075618 tumor 23588415
ENSG00000075618 tumour 23633513
ENSG00000075618 tumours 23754570
ENSG00000075618 thyroid cancers 23815851
ENSG00000075618 thyroid cancers 23815863
ENSG00000075618 breast cancer 23835592
ENSG00000075618 colorectal cancers 23899558
ENSG00000075618 triple negative breast cancer 23986556
ENSG00000075618 non-small-cell lung cancer 24070574
ENSG00000075618 tumor 24085294
ENSG00000075618 colorectal cancer 24105619
ENSG00000075618 cancer 24187485
ENSG00000075618 tumour 24196787
ENSG00000075618 breast cancer 24235142
ENSG00000075618 tumour 24244855
ENSG00000075618 bone cancer 24288084
ENSG00000075618 non-small cell lung cancer 24300277
ENSG00000075618 tumour 24300716
ENSG00000075618 cancer 24378809
ENSG00000075618 prostate cancer 24414419
ENSG00000075618 cancers 24460279
ENSG00000075618 Pancreatic Cancer 24462734
ENSG00000075618 cancer 24496629
ENSG00000075618 tumor 24527098
ENSG00000075618 tumors 24574163
ENSG00000075618 tumor 24599125
ENSG00000075618 breast cancer 24605901
ENSG00000075618 colorectal cancer 24642628
ENSG00000075618 urinary bladder cancer 24649164
ENSG00000075618 cancer 24694065
ENSG00000075618 tumor 24696454
ENSG00000075618 tumors 24843202
ENSG00000075618 ovarian cancers 24848881
ENSG00000075618 cancer 24929653
ENSG00000075618 tumor 24932286
ENSG00000075618 tumour 24977742
ENSG00000075618 tumor 24993803
ENSG00000075618 breast tumors 25003838
ENSG00000075618 tumor 25007006
ENSG00000075618 tumors 25097648
ENSG00000075618 bladder cancer 25104873
ENSG00000075618 tumor 25105941
ENSG00000075618 breast cancer 25117814
ENSG00000075618 cancers 25124875
ENSG00000075618 ovarian tumors 25155376
ENSG00000075618 tumor 25197351
ENSG00000075618 tumor 25198665
ENSG00000075618 breast cancer 25213863
ENSG00000075618 cancers 25231007
ENSG00000075618 tumor 25269996
ENSG00000075618 breast cancer 25327793
ENSG00000075618 cancer 25354783
ENSG00000075618 tumor 25357101
ENSG00000075618 colorectal cancer 25370828
ENSG00000075618 gastric cancer 25433493
ENSG00000075618 cancer 25485970
ENSG00000075618 tumour 25535872
ENSG00000075618 colorectal cancer 25621061
ENSG00000075618 tumor 25691058
ENSG00000075618 colorectal cancer 25692620
ENSG00000075618 breast cancer 25721973
ENSG00000075618 tumor 25734659
ENSG00000075618 tumor 25781684
ENSG00000075618 cancer 25808493
ENSG00000075618 gastric cancer 25815687
ENSG00000075618 tumor 25816323
ENSG00000075618 tumors 25818780
ENSG00000075618 tumor 25882880
ENSG00000075618 tumours 2598175
ENSG00000075618 Gastric Cancer 25992623
ENSG00000075618 tumor 25999065
ENSG00000075618 tumor 26010149
ENSG00000075618 tumor 26036261
ENSG00000075618 cancer 26058854
ENSG00000075618 cancer 26079945
ENSG00000075618 tumour 26081695
ENSG00000075618 cancer 26167915
ENSG00000075618 non-small cell lung cancer 26170694
ENSG00000075618 breast cancer 26170987
ENSG00000075618 cancers 26173501
ENSG00000075618 non-small cell lung cancer 26211585
ENSG00000075618 cancers 26225692
ENSG00000075618 non-small-cell lung cancer 26238532
ENSG00000075618 tumors 26239622
ENSG00000075618 gastric cancer 26269751
ENSG00000075618 lung cancer 26309531
ENSG00000075618 tumor 26345720
ENSG00000075618 Breast Cancer 26349603
ENSG00000075618 prostate cancer 26353734
ENSG00000075618 gastric cancer 26359764
ENSG00000075618 colorectal cancer 26362504
ENSG00000075618 tumours 26362828
ENSG00000075618 tumor 26363219
ENSG00000075618 cancer 26399408
ENSG00000075618 lung cancer 26451116
ENSG00000075618 tumor 26503504
ENSG00000075618 cancer 26522130
ENSG00000075618 ovarian cancer 26526349
ENSG00000075618 tumour 26542021
ENSG00000075618 bladder cancer 26544536
ENSG00000075618 tumor 26647829
ENSG00000075618 lung cancer 26657507
ENSG00000075618 thyroid cancer 26714602
ENSG00000075618 breast cancer 26719157
ENSG00000075618 gastric cancer 26743780
ENSG00000075618 tumor 26833854
ENSG00000075618 prostate cancer 26856960
ENSG00000075618 breast cancer 26883198
ENSG00000075618 non-small cell lung cancer 26886283
ENSG00000075618 Tumors 26918943
ENSG00000075618 Cancer 26945069
ENSG00000075618 lung cancer 26950100
ENSG00000075618 cancers 27014223
ENSG00000075618 breast cancer 27036017
ENSG00000075618 tumor 27042104
ENSG00000075618 tumor 27071719
ENSG00000075618 colon cancer 27117176
ENSG00000075618 triple-negative breast cancer 27184764
ENSG00000075618 non-small cell lung cancer 27356635
ENSG00000075618 tumor 27359377
ENSG00000075618 tumors 27402219
ENSG00000075618 tumors 27406586
ENSG00000075618 tumor 27426109
ENSG00000075618 colorectal cancer 27488323
ENSG00000075618 Breast Cancer 27502039
ENSG00000075618 cancers 27554857
ENSG00000075618 tumor 27566402
ENSG00000075618 cancers 27680563
ENSG00000075618 cancer 27698883
ENSG00000075618 malignant tumors 27776189
ENSG00000075618 cancer 27787561
ENSG00000075618 cancer 27819326
ENSG00000075618 cancer 27879315
ENSG00000075618 pancreatic cancer 27900027
ENSG00000075618 non small cell lung cancer 27900045
ENSG00000075618 Tumor 27956255
ENSG00000075618 cancer 28060557
ENSG00000075618 cancer 28176896
ENSG00000075618 breast cancer 28186968
ENSG00000075618 tumors 28208778
ENSG00000075618 nonsmall cell lung cancer 28230028
ENSG00000075618 cancer 28251354
ENSG00000075618 tumor 28272224
ENSG00000075618 cancer 28288473
ENSG00000075618 colorectal cancers 28350509
ENSG00000075618 cancers 28393215
ENSG00000075618 gastric cancer 28428713
ENSG00000075618 cancer 28545132
ENSG00000075618 Tumours 28607544
ENSG00000075618 non-small cell lung cancer 28653739
ENSG00000075618 tumor 28704324
ENSG00000075618 tumor 28791340
ENSG00000075618 cancers 28855604
ENSG00000075618 ovarian cancer 28881818
ENSG00000075618 prostate cancer 28922730
ENSG00000075618 tumor 28965626
ENSG00000075618 colorectal cancer 29039557
ENSG00000075618 breast cancer 29052029
ENSG00000075618 tumor 29052088
ENSG00000075618 tumors 29065267
ENSG00000075618 tumors 29088820
ENSG00000075618 Cancer 29101304
ENSG00000075618 tumor 29142206
ENSG00000075618 tumor 29148041
ENSG00000075618 breast cancer 29158783
ENSG00000075618 breast cancer 29162880
ENSG00000075618 gastric cancer 29285273
ENSG00000075618 tumor 29299131
ENSG00000075618 cancer 29371698
ENSG00000075618 tumors 29430188
ENSG00000075618 non-small cell lung cancer 29458026
ENSG00000075618 cancers 29506475
ENSG00000075618 cancer 29568562
ENSG00000075618 tumors 29568938
ENSG00000075618 gastric cancer 29572117
ENSG00000075618 tumor 29573988
ENSG00000075618 tumor 29593421
ENSG00000075618 bone cancer 29615865
ENSG00000075618 bladder cancer 29618386
ENSG00000075618 tumors 29851865
ENSG00000075618 cancer 29861382
ENSG00000075618 cancer 29870655
ENSG00000075618 colorectal cancer 29888780
ENSG00000075618 lung cancer 29899821
ENSG00000075618 cancers 29970086
ENSG00000075618 cancer 29970282
ENSG00000075618 cancer 29970665
ENSG00000075618 tumour 29976164
ENSG00000075618 invasive breast cancer 29976963
ENSG00000075618 tumor 29992166
ENSG00000075618 cancer 30056535
ENSG00000075618 cancer 30094535
ENSG00000075618 tumor 30185791
ENSG00000075618 Ovarian Cancer 30231243
ENSG00000075618 cancer 30232331
ENSG00000075618 tumor 30341010
ENSG00000075618 breast cancer 30353022
ENSG00000075618 cancer 30370259
ENSG00000075618 tumor 30396077
ENSG00000075618 Cancer 30396928
ENSG00000075618 Tumor 30397076
ENSG00000075618 breast cancer 30417585
ENSG00000075618 tumor 30426092
ENSG00000075618 tumor 30448221
ENSG00000075618 Tumor 30476173
ENSG00000075618 cancer 30542700
ENSG00000075618 cervical cancer 30613006
ENSG00000075618 tumor 30654764
ENSG00000075618 cardia cancer 30675241
ENSG00000075618 Cancer 30719702
ENSG00000075618 tumor 30773430
ENSG00000075618 cancer 30797592
ENSG00000075618 cancers 30815429
ENSG00000075618 tumor 30823924
ENSG00000075618 cancer 31043585
ENSG00000075618 lung cancer 31191004
ENSG00000075618 tumor 31268159
ENSG00000075618 cervical cancer 31271056
ENSG00000075618 Breast Cancer 31273628
ENSG00000075618 tumors 31322546
ENSG00000075618 tumors 31409279
ENSG00000075618 tumor 31509745
ENSG00000075618 tumor 31616184
ENSG00000075618 tumour 31783819
ENSG00000075618 skin cancer 31868059
ENSG00000075618 tumor 31889512
ENSG00000075618 tumor 31951853
ENSG00000075618 tumour 3814471
ENSG00000075618 tumour 3817870
ENSG00000075618 tumour 7150472
ENSG00000075618 Tumour 7627527
ENSG00000075618 tumour 7632776
ENSG00000075618 tumour 7659096
ENSG00000075618 tumors 7889538
ENSG00000075618 tumour 8077056
ENSG00000075618 tumour 8198964
ENSG00000075618 tumour 8440265
ENSG00000075618 tumors 8587370
ENSG00000075618 tumours 8611432
ENSG00000075618 tumor 8647875
ENSG00000075618 Tumour 8763871
ENSG00000075618 Tumour 8782666
ENSG00000075618 tumor 9322759
ENSG00000075618 tumour 9335456
ENSG00000075618 tumour 9365170
ENSG00000075618 tumour 9935213
ENSG00000075618 tumor PMC1386690
ENSG00000075618 cancer PMC4669991
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000075618 SARC 0.0016 high
ENSG00000075618 STAD 0.017 high
ENSG00000075618 UVM 0.04 high
ENSG00000075618 PAAD 0.0065 high
ENSG00000075618 UCEC 0.0066 high
ENSG00000075618 THCA 0.0011 high
ENSG00000075618 LGG 0.00073 high
ENSG00000075618 LUSC 0.021 high
ENSG00000075618 HNSC 0.00044 high
ENSG00000075618 KICH 0.0061 low
ENSG00000075618 PCPG 0.025 low
ENSG00000075618 THYM 0.00051 high
ENSG00000075618 COAD 0.028 high
ENSG00000075618 ESCA 0.036 low
ENSG00000075618 DLBC 0.026 low
ENSG00000075618 BLCA 0.02 high
ENSG00000075618 LAML 0.017 low
ENSG00000075618 SKCM 0.036 high
ENSG00000075618 CESC 0.00047 high
ENSG00000075618 LIHC 0.00087 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000075618 SKCM Amp 3.430941 0.201106 0.714524 0.569482
ENSG00000075618 HNSC Amp 0.864707 0.120289 0.516714 0.402299
ENSG00000075618 TGCT Amp 1.710327 0.165017 0.555449 0.840000
ENSG00000075618 STAD Amp 2.102843 0.172510 0.530871 0.519274
ENSG00000075618 UCEC Del 1.813546 0.061464 0.504243 0.115028
ENSG00000075618 OV Del 23.851632 0.409126 0.622813 0.435233