Ensembl ID ENSG00000075239 Gene ID 38 Accession 93
Gene Symbol ACAT1 Alias T2;MAT;ACAT;THIL Full Name acetyl-CoA acetyltransferase 1
Position 11 : 108116695 - 108147603 Length 30909 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009]

ENSG00000075239 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000075239 ACAT1 -1.2 3.93e-21 KIRC
ENSG00000075239 ACAT1 -1.4 1.31e-41 HNSC
ENSG00000075239 ACAT1 -0.9 1.58e-32 BRCA
ENSG00000075239 ACAT1 -1.3 2.57e-38 COAD
ENSG00000075239 ACAT1 -0.9 3.24e-27 LUSC
ENSG00000075239 ACAT1 -1.4 3.15e-25 LIHC
ENSG00000075239 ACAT1 -0.9 1.54e-14 STAD
ENSG00000075239 ACAT1 -1.6 1.07e-13 ESCA
ENSG00000075239 ACAT1 -3.5 3.99e-21 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000075239 ACAT1 tumour 6130780
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000075239 ACAT1 SARC 0.047 low
ENSG00000075239 ACAT1 PAAD 0.016 low
ENSG00000075239 ACAT1 ACC 0.021 low
ENSG00000075239 ACAT1 HNSC 0.0094 high
ENSG00000075239 ACAT1 LUAD 0.0022 low
ENSG00000075239 ACAT1 THYM 0.015 high
ENSG00000075239 ACAT1 BRCA 0.0067 high
ENSG00000075239 ACAT1 COAD 0.023 low
ENSG00000075239 ACAT1 ESCA 0.014 high
ENSG00000075239 ACAT1 OV 0.048 high
ENSG00000075239 ACAT1 PRAD 0.0019 high
ENSG00000075239 ACAT1 BLCA 0.0083 high
ENSG00000075239 ACAT1 GBM 0.0091 low
ENSG00000075239 ACAT1 CESC 0.036 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000075239 ACAT1 LUSC Del 1.783745 0.080604 0.340165 0.337325
ENSG00000075239 ACAT1 LUAD Del 4.432449 0.088542 0.339122 0.228682
ENSG00000075239 ACAT1 CESC Del 21.210852 0.262038 0.559070 0.522034
ENSG00000075239 ACAT1 KIRP Del 4.468698 0.060899 0.575535 0.107639
ENSG00000075239 ACAT1 SARC Del 5.267688 0.221164 0.548319 0.435798
ENSG00000075239 ACAT1 ESCA Del 1.738121 0.125917 0.443731 0.407609
ENSG00000075239 ACAT1 SKCM Del 21.620776 0.249275 0.547434 0.544959
ENSG00000075239 ACAT1 HNSC Del 15.071560 0.147879 0.437439 0.459770
ENSG00000075239 ACAT1 LIHC Del 1.428680 0.077541 0.477968 0.243243
ENSG00000075239 ACAT1 TGCT Del 1.769232 0.082281 0.465351 0.793333
ENSG00000075239 ACAT1 BLCA Del 2.689199 0.107734 0.407738 0.365196
ENSG00000075239 ACAT1 BRCA Del 48.187304 0.222043 0.528004 0.487037
ENSG00000075239 ACAT1 STAD Del 1.446942 0.071440 0.351651 0.204082
ENSG00000075239 ACAT1 PRAD Del 1.346327 0.080539 0.486198 0.081301
ENSG00000075239 ACAT1 UCEC Del 2.061589 0.063874 0.523182 0.163265
ENSG00000075239 ACAT1 MESO Del 0.687254 0.123198 0.493509 0.149425
ENSG00000075239 ACAT1 OV Del 0.733379 0.174832 0.528879 0.298791