Ensembl ID ENSG00000074071 Gene ID 65993 Accession 16618
Gene Symbol MRPS34 Alias mS34;MRPS12;COXPD32;MRP-S12;MRP-S34 Full Name mitochondrial ribosomal protein S34
Position 16 : 1771890 - 1773150 Length 1261 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Non-canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

ENSG00000074071 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000074071 MRPS34 1.39 9.60e-73 BRCA
ENSG00000074071 MRPS34 0.77 2.68e-11 KICH
ENSG00000074071 MRPS34 1.00 2.26e-35 LUSC
ENSG00000074071 MRPS34 1.19 2.37e-19 UCEC
ENSG00000074071 MRPS34 0.82 4.32e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000074071 MRPS34 GBM 26781422
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000074071 MRPS34 MESO 0.018 low
ENSG00000074071 MRPS34 STAD 0.015 low
ENSG00000074071 MRPS34 CHOL 0.0058 high
ENSG00000074071 MRPS34 PAAD 0.034 low
ENSG00000074071 MRPS34 UCEC 0.023 low
ENSG00000074071 MRPS34 READ 0.032 high
ENSG00000074071 MRPS34 LUAD 0.037 high
ENSG00000074071 MRPS34 OV 0.014 low
ENSG00000074071 MRPS34 KIRC 0.0016 high
ENSG00000074071 MRPS34 LAML 0.00023 high
ENSG00000074071 MRPS34 LIHC 0.015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000074071 MRPS34 LUSC Del 1.972969 0.082765 0.349864 0.371257
ENSG00000074071 MRPS34 ESCA Del 0.634607 0.094143 0.403399 0.342391
ENSG00000074071 MRPS34 BLCA Del 6.886923 0.152314 0.386934 0.414216
ENSG00000074071 MRPS34 STAD Del 1.640104 0.073895 0.376643 0.258503
ENSG00000074071 MRPS34 OV Del 1.119857 0.184555 0.565852 0.545769