Ensembl ID ENSG00000072506 Gene ID 3028 Accession 4800
Gene Symbol HSD17B10 Alias ABAD;CAMR;ERAB;HCD2;MHBD;HADH2;MRPP2;MRX17;MRX31;SCHAD;MRXS10;SDR5C1;HSD10MD;17b-HSD10;DUPXp11.22 Full Name hydroxysteroid 17-beta dehydrogenase 10
Position X : 53431258 - 53434370 Length 3113 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]

ENSG00000072506 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000072506 -0.5 3.59e-14 KIRC
ENSG00000072506 0.86 4.09e-36 BRCA
ENSG00000072506 0.83 3.71e-11 COAD
ENSG00000072506 -0.7 1.53e-15 KICH
ENSG00000072506 0.83 7.54e-25 LUSC
ENSG00000072506 1.54 1.70e-13 GBM
ENSG00000072506 1.16 4.97e-22 UCEC
ENSG00000072506 -1.7 1.97e-22 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000072506 cancer 11552679
ENSG00000072506 prostate tumor 24244276
ENSG00000072506 prostate cancer 28188816
ENSG00000072506 HNSCC 31501464
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000072506 STAD 0.025 low
ENSG00000072506 UVM 0.0043 high
ENSG00000072506 PAAD 0.0045 low
ENSG00000072506 LUSC 0.019 low
ENSG00000072506 HNSC 0.042 low
ENSG00000072506 KIRP 0.012 low
ENSG00000072506 KICH 0.0017 high
ENSG00000072506 OV 0.0039 low
ENSG00000072506 KIRC 0.0026 high
ENSG00000072506 TGCT 0.0092 low
ENSG00000072506 LAML 1e-04 high
ENSG00000072506 SKCM 0.037 high
ENSG00000072506 CESC 0.00014 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency