Ensembl ID ENSG00000072274 Gene ID 7037 Accession 11763
Gene Symbol TFRC Alias T9;TR;TFR;p90;CD71;TFR1;TRFR;IMD46 Full Name transferrin receptor
Position 3 : 196012511 - 196082096 Length 69586 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

ENSG00000072274 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000072274 1.30 3.49e-15 HNSC
ENSG00000072274 1.08 2.18e-27 BRCA
ENSG00000072274 1.45 1.18e-15 LUSC
ENSG00000072274 0.85 4.26e-11 LIHC
ENSG00000072274 1.60 3.22e-18 UCEC
ENSG00000072274 -1.0 9.68e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000072274 GBMs 10427128
ENSG00000072274 tumour 10492640
ENSG00000072274 acute myeloid leukemia (AML) 10684063
ENSG00000072274 tumors 10995873
ENSG00000072274 tumors 11300100
ENSG00000072274 breast cancer 11497259
ENSG00000072274 AML 11722405
ENSG00000072274 cancer 12102125
ENSG00000072274 cancer 12104045
ENSG00000072274 cancer 12149472
ENSG00000072274 breast cancer 12489850
ENSG00000072274 breast cancer 12676065
ENSG00000072274 cancer 1289186
ENSG00000072274 acute myeloid leukemia (AML) 12921947
ENSG00000072274 tumor 12939468
ENSG00000072274 tumor 14661179
ENSG00000072274 cancer 14726636
ENSG00000072274 cancers 14965443
ENSG00000072274 tumors 1499078
ENSG00000072274 AML 15015967
ENSG00000072274 tumor 1517150
ENSG00000072274 tumours 15177502
ENSG00000072274 cancer 15281088
ENSG00000072274 tumor 15587919
ENSG00000072274 Ovarian Cancer 15668490
ENSG00000072274 cancer 15748688
ENSG00000072274 cancers 15775751
ENSG00000072274 tumour 15939240
ENSG00000072274 cancer 16012706
ENSG00000072274 malignant tumors 1607823
ENSG00000072274 lung cancer 16092918
ENSG00000072274 cancers 16103367
ENSG00000072274 tumor 16111806
ENSG00000072274 tumor 16326028
ENSG00000072274 tumors 16341531
ENSG00000072274 tumor 16476163
ENSG00000072274 tumor 16481319
ENSG00000072274 tumor 16510596
ENSG00000072274 breast cancer 16721748
ENSG00000072274 tumour 16792817
ENSG00000072274 prostate cancer 1688956
ENSG00000072274 cancer 16904380
ENSG00000072274 tumor 16920030
ENSG00000072274 tumor 16948919
ENSG00000072274 tumor 17226956
ENSG00000072274 tumor 17257079
ENSG00000072274 tumor 17266924
ENSG00000072274 tumor 17283149
ENSG00000072274 tumour 1735731
ENSG00000072274 tumor 17428703
ENSG00000072274 tumor 17498801
ENSG00000072274 DLBCL 17705020
ENSG00000072274 tumors 17726528
ENSG00000072274 tumor 17927572
ENSG00000072274 cancer 18025284
ENSG00000072274 tumor 18041635
ENSG00000072274 tumour 18042273
ENSG00000072274 cervical cancer 18217980
ENSG00000072274 cancer 18345610
ENSG00000072274 cancer 18367876
ENSG00000072274 HNSCCs 18384723
ENSG00000072274 tumors 18423048
ENSG00000072274 tumors 18483503
ENSG00000072274 cancer 18811052
ENSG00000072274 cancer 18817895
ENSG00000072274 tumor 18829060
ENSG00000072274 Cancer 19006645
ENSG00000072274 cancer 19019709
ENSG00000072274 tumor 19066835
ENSG00000072274 tumor 19107352
ENSG00000072274 cancer 19135902
ENSG00000072274 tumor 19198573
ENSG00000072274 cancer 19267452
ENSG00000072274 tumor 19308738
ENSG00000072274 brain tumors 19386095
ENSG00000072274 tumor 19429296
ENSG00000072274 tumors 19430294
ENSG00000072274 tumor 19743956
ENSG00000072274 tumor 19825853
ENSG00000072274 tumors 19957205
ENSG00000072274 ovarian cancer 20060458
ENSG00000072274 tumor 20130467
ENSG00000072274 tumor 20137162
ENSG00000072274 tumor 20346225
ENSG00000072274 AML 20368581
ENSG00000072274 breast cancer 20387095
ENSG00000072274 tumor 20392994
ENSG00000072274 Tumors 20405006
ENSG00000072274 tumor 20406704
ENSG00000072274 hematopoietic cancer 20530676
ENSG00000072274 cancer 20574452
ENSG00000072274 cancer 20631077
ENSG00000072274 cancer 20657468
ENSG00000072274 tumors 20685917
ENSG00000072274 tumor 20698697
ENSG00000072274 breast cancer 20723262
ENSG00000072274 tumor 21083917
ENSG00000072274 cancer 21125861
ENSG00000072274 astrocytic tumors 21183793
ENSG00000072274 cancers 21297444
ENSG00000072274 malignant tumors 21323588
ENSG00000072274 cancer 21350890
ENSG00000072274 tumor 21440638
ENSG00000072274 tumor 2145079
ENSG00000072274 brain-tumor 2159987
ENSG00000072274 breast cancer 21702980
ENSG00000072274 cancers 21777476
ENSG00000072274 tumor 21820086
ENSG00000072274 breast cancer 21849092
ENSG00000072274 cancer 21851850
ENSG00000072274 breast cancer 21859709
ENSG00000072274 cancer 21915296
ENSG00000072274 tumor 22069564
ENSG00000072274 tumor 22069717
ENSG00000072274 cancer 22111834
ENSG00000072274 breast cancer 22115965
ENSG00000072274 tumours 22117970
ENSG00000072274 cancer 22174561
ENSG00000072274 thyroid cancer 22188859
ENSG00000072274 tumor 22355336
ENSG00000072274 cancer 22496980
ENSG00000072274 cancers 22616905
ENSG00000072274 tumor 22670765
ENSG00000072274 tumor 22695343
ENSG00000072274 tumour 22706697
ENSG00000072274 cancer 22732733
ENSG00000072274 tumors 22761861
ENSG00000072274 cancer 22808075
ENSG00000072274 tumors 22896707
ENSG00000072274 cancers 22900042
ENSG00000072274 tumors 22941037
ENSG00000072274 prostate cancer 23001181
ENSG00000072274 tumour 23016877
ENSG00000072274 tumor 23192001
ENSG00000072274 cancer 23204307
ENSG00000072274 cancer 23328867
ENSG00000072274 cancer 23344001
ENSG00000072274 tumor 23545225
ENSG00000072274 tumors 23606622
ENSG00000072274 tumor 23723739
ENSG00000072274 tumors 23812305
ENSG00000072274 tumor 23840214
ENSG00000072274 colorectal cancer 23904384
ENSG00000072274 cancer 24078156
ENSG00000072274 cancer 24107468
ENSG00000072274 cancer 24109228
ENSG00000072274 breast cancer 24285726
ENSG00000072274 tumors 24325630
ENSG00000072274 cancer 24348038
ENSG00000072274 cancer 24436117
ENSG00000072274 colon cancer 24437279
ENSG00000072274 cancer 24472870
ENSG00000072274 tumor 24478715
ENSG00000072274 invasive breast cancer 24512624
ENSG00000072274 cancer 24525050
ENSG00000072274 cancers 24659461
ENSG00000072274 tumor 24683542
ENSG00000072274 colorectal cancer 24687888
ENSG00000072274 tumor 2479430
ENSG00000072274 tumors 24811110
ENSG00000072274 tumor 24890018
ENSG00000072274 tumor 24901155
ENSG00000072274 pancreatic cancers 24909164
ENSG00000072274 tumor 24962356
ENSG00000072274 prostate cancer 25080433
ENSG00000072274 cancer 25097549
ENSG00000072274 lung cancer 25117307
ENSG00000072274 tumor 25213357
ENSG00000072274 GBM 25356585
ENSG00000072274 tumor 25360666
ENSG00000072274 tumor 25400528
ENSG00000072274 breast tumors 25445497
ENSG00000072274 pancreatic cancer 25460304
ENSG00000072274 Cancer 25476483
ENSG00000072274 cancer 25519743
ENSG00000072274 Tumors 25520556
ENSG00000072274 cancer 25604962
ENSG00000072274 cancer 25609961
ENSG00000072274 cancer 25656384
ENSG00000072274 cancer 25733832
ENSG00000072274 breast cancer 25778692
ENSG00000072274 cancer 25803700
ENSG00000072274 tumor 25811613
ENSG00000072274 cancer 25839091
ENSG00000072274 Cancer 25861527
ENSG00000072274 pancreatic cancer 25893775
ENSG00000072274 tumors 25919089
ENSG00000072274 tumour 25980759
ENSG00000072274 tumor 26022978
ENSG00000072274 tumor 26045659
ENSG00000072274 tumor 26213467
ENSG00000072274 tumour 26227403
ENSG00000072274 tumor 26232328
ENSG00000072274 cancer 26325374
ENSG00000072274 cancer 26342440
ENSG00000072274 tumors 26426994
ENSG00000072274 cancers 26434535
ENSG00000072274 cancer 26487967
ENSG00000072274 tumors 26502166
ENSG00000072274 tumor 26523294
ENSG00000072274 cancer 26594360
ENSG00000072274 lung cancer 26604751
ENSG00000072274 liver cancer 26657500
ENSG00000072274 pancreatic cancer 26842750
ENSG00000072274 cancer 26869514
ENSG00000072274 cancer 26955956
ENSG00000072274 tumors 26956814
ENSG00000072274 tumor 26959856
ENSG00000072274 tumour 26961594
ENSG00000072274 tumor 27046157
ENSG00000072274 cancer 27049534
ENSG00000072274 tumor 27109317
ENSG00000072274 Breast cancer 27223606
ENSG00000072274 cancer 27251028
ENSG00000072274 tumors 27384479
ENSG00000072274 tumors 27432745
ENSG00000072274 tumors 27468886
ENSG00000072274 cancer 27523281
ENSG00000072274 cancer 27574446
ENSG00000072274 cancer 27624789
ENSG00000072274 tumor 27735873
ENSG00000072274 tumor 27739410
ENSG00000072274 cancer 27834817
ENSG00000072274 GBM 27898674
ENSG00000072274 cancer 27959443
ENSG00000072274 tumors 27977155
ENSG00000072274 breast cancers 28028679
ENSG00000072274 cancer 28065783
ENSG00000072274 tumor 28122339
ENSG00000072274 cancer 28184946
ENSG00000072274 tumors 28216608
ENSG00000072274 tumor 28223798
ENSG00000072274 pancreatic cancer 28262749
ENSG00000072274 colorectal cancer 28281325
ENSG00000072274 lung cancer 28290155
ENSG00000072274 cancer 28319807
ENSG00000072274 cancer 28324424
ENSG00000072274 malignant tumor 28344260
ENSG00000072274 tumor 28347103
ENSG00000072274 tumors 28389657
ENSG00000072274 brain tumor 28412744
ENSG00000072274 tumor 28484093
ENSG00000072274 malignant tumor 28491487
ENSG00000072274 cancer 28562667
ENSG00000072274 cervicalcancer 28635657
ENSG00000072274 tumor 28718812
ENSG00000072274 tumor 28790402
ENSG00000072274 brain tumors 28837569
ENSG00000072274 tumors 28848040
ENSG00000072274 cancer 28854413
ENSG00000072274 tumors 28893116
ENSG00000072274 tumors 2899182
ENSG00000072274 tumor 29042776
ENSG00000072274 cancer 29046922
ENSG00000072274 tumor 29088257
ENSG00000072274 tumor 29088799
ENSG00000072274 tumor 29091247
ENSG00000072274 prostate cancer 29137259
ENSG00000072274 tumor 29218233
ENSG00000072274 tumour 29247214
ENSG00000072274 cancer 29271190
ENSG00000072274 cancer 29278317
ENSG00000072274 cancer 29286585
ENSG00000072274 cancer 29291011
ENSG00000072274 tumor 29315261
ENSG00000072274 cancer 29421281
ENSG00000072274 cancer 29426509
ENSG00000072274 cancer 29433357
ENSG00000072274 cancer 29522834
ENSG00000072274 tumor 29538454
ENSG00000072274 malignant tumors 29541866
ENSG00000072274 cervical cancer 29572030
ENSG00000072274 tumor 29592883
ENSG00000072274 tumor 29629632
ENSG00000072274 cancer 29649293
ENSG00000072274 tumor 29650959
ENSG00000072274 cancer 29654211
ENSG00000072274 cancer 29698587
ENSG00000072274 GBM 29730475
ENSG00000072274 tumors 29742327
ENSG00000072274 liver cancers 29747160
ENSG00000072274 tumors 29872621
ENSG00000072274 GBM 29916012
ENSG00000072274 tumour 2996121
ENSG00000072274 tumor 29963255
ENSG00000072274 tumor 30056091
ENSG00000072274 cancer 30065256
ENSG00000072274 tumor 3009202
ENSG00000072274 cancer 30228208
ENSG00000072274 cancer 30259230
ENSG00000072274 cervical cancer 30344797
ENSG00000072274 cancer 30384431
ENSG00000072274 tumor 30395963
ENSG00000072274 cancer 30429878
ENSG00000072274 tumor 30464450
ENSG00000072274 tumor 30510417
ENSG00000072274 tumor 30523361
ENSG00000072274 cancer 30562983
ENSG00000072274 cancer 30581704
ENSG00000072274 thyroid cancer 30584304
ENSG00000072274 tumor 30591630
ENSG00000072274 tumor 30604643
ENSG00000072274 tumor 30633527
ENSG00000072274 tumor 30641920
ENSG00000072274 cervical cancers 30651591
ENSG00000072274 Brain tumors 30680316
ENSG00000072274 tumor 30782157
ENSG00000072274 cancer 30941302
ENSG00000072274 GBM 30996239
ENSG00000072274 tumors 31040647
ENSG00000072274 breast cancer 31042781
ENSG00000072274 tumor 31083487
ENSG00000072274 tumor 31100837
ENSG00000072274 liver tumor 31102765
ENSG00000072274 tumor 31118631
ENSG00000072274 cancer 31137689
ENSG00000072274 tumours 31137744
ENSG00000072274 breast cancer 31173262
ENSG00000072274 breast cancer 31213851
ENSG00000072274 tumor 31216851
ENSG00000072274 colon cancer 31248025
ENSG00000072274 cancer 31284665
ENSG00000072274 tumor 31293575
ENSG00000072274 cancer 31301427
ENSG00000072274 cancer 31311812
ENSG00000072274 tumors 31366108
ENSG00000072274 tumors 31372038
ENSG00000072274 tumor 31382388
ENSG00000072274 tumors 31409279
ENSG00000072274 tumor 31423412
ENSG00000072274 GBM 31433156
ENSG00000072274 cancer 31435920
ENSG00000072274 brain tumors 31462642
ENSG00000072274 tumor 31484533
ENSG00000072274 breast cancer 31494184
ENSG00000072274 AML 31519186
ENSG00000072274 tumor 31523389
ENSG00000072274 tumor 31527483
ENSG00000072274 tumor 31546149
ENSG00000072274 tumor 31574945
ENSG00000072274 triple-negative breast cancer 31597263
ENSG00000072274 tumor 31649854
ENSG00000072274 tumour 3165309
ENSG00000072274 tumor 31654226
ENSG00000072274 cancer 31680182
ENSG00000072274 tumors 31693515
ENSG00000072274 Breast Cancer 31694367
ENSG00000072274 tumor 31695794
ENSG00000072274 tumors 31789393
ENSG00000072274 cancer 31824148
ENSG00000072274 colorectal cancer 31923538
ENSG00000072274 AML 3291932
ENSG00000072274 tumor 3807258
ENSG00000072274 cancer 7890992
ENSG00000072274 tumor 7897271
ENSG00000072274 tumor 8050820
ENSG00000072274 tumors 8485201
ENSG00000072274 tumor 8548750
ENSG00000072274 lung cancer 9192985
ENSG00000072274 tumors 9428630
ENSG00000072274 cancer 9549364
ENSG00000072274 bladder cancer 9722768
ENSG00000072274 tumor 9935054
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000072274 head and neck squamous cell carcinoma missense_variant 0.6702% (5/746) 1 entry
ENSG00000072274 colon adenocarcinoma missense_variant 2.632% (19/722) 3 entries
ENSG00000072274 melanoma sequence_alteration 5.941% (6/101) 2 entries
ENSG00000072274 colon adenocarcinoma sequence_alteration 2.632% (19/722) 3 entries
ENSG00000072274 esophageal adenocarcinoma sequence_alteration 2.283% (10/438) 1 entry
ENSG00000072274 prostate carcinoma sequence_alteration 1.174% (5/426) 1 entry
ENSG00000072274 colorectal adenocarcinoma frameshift_variant 2.548% (29/1138) 1 entry
ENSG00000072274 small cell lung carcinoma missense_variant 1.254% (4/319) 2 entries
ENSG00000072274 colorectal adenocarcinoma missense_variant 2.548% (29/1138) 2 entries
ENSG00000072274 rectal adenocarcinoma missense_variant 2.262% (5/221) 1 entry
ENSG00000072274 colorectal adenocarcinoma stop_gained 2.548% (29/1138) 1 entry
ENSG00000072274 lung adenocarcinoma missense_variant 1.118% (13/1163) 3 entries
ENSG00000072274 clear cell renal carcinoma missense_variant 0.3628% (5/1378) 1 entry
ENSG00000072274 ovarian serous adenocarcinoma missense_variant 0.7429% (5/673) 2 entries
ENSG00000072274 prostate adenocarcinoma sequence_alteration 1.582% (23/1454) 1 entry
ENSG00000072274 head and neck squamous cell carcinoma sequence_alteration 0.6702% (5/746) 1 entry
ENSG00000072274 lung adenocarcinoma sequence_alteration 1.118% (13/1163) 3 entries
ENSG00000072274 breast carcinoma missense_variant 0.2835% (4/1411) 1 entry
ENSG00000072274 melanoma missense_variant 5.941% (6/101) 2 entries
ENSG00000072274 rectal adenocarcinoma sequence_alteration 2.262% (5/221) 1 entry
ENSG00000072274 cecum adenocarcinoma missense_variant 2.4% (3/125) 2 entries
ENSG00000072274 skin melanoma missense_variant 1.034% (10/967) 4 entries
ENSG00000072274 colorectal adenocarcinoma sequence_alteration 2.548% (29/1138) 2 entries
ENSG00000072274 esophageal squamous cell carcinoma missense_variant 1.037% (7/675) 4 entries
ENSG00000072274 esophageal adenocarcinoma missense_variant 2.283% (10/438) 1 entry
ENSG00000072274 primary peritoneal carcinoma (disease) missense_variant 100.0% (1/1) 1 entry
ENSG00000072274 Merkel cell skin cancer sequence_alteration 3.333% (1/30) 1 entry
ENSG00000072274 Ampulla of Vater Carcinoma missense_variant 1.176% (1/85) 1 entry
ENSG00000072274 skin melanoma sequence_alteration 1.034% (10/967) 1 entry
ENSG00000072274 osteosarcoma sequence_alteration 1.724% (2/116) 1 entry
ENSG00000072274 female breast carcinoma missense_variant 0.7491% (2/267) 1 entry
ENSG00000072274 clear cell renal carcinoma frameshift_variant 0.3628% (5/1378) 1 entry
ENSG00000072274 diffuse gastric adenocarcinoma sequence_alteration 1.266% (1/79) 1 entry
ENSG00000072274 colon adenocarcinoma frameshift_variant 2.632% (19/722) 1 entry
ENSG00000072274 female breast carcinoma sequence_alteration 0.7491% (2/267) 1 entry
ENSG00000072274 cecum adenocarcinoma sequence_alteration 2.4% (3/125) 1 entry
ENSG00000072274 osteosarcoma missense_variant 1.724% (2/116) 1 entry
ENSG00000072274 gastric intestinal type adenocarcinoma sequence_alteration 1.176% (1/85) 1 entry
ENSG00000072274 non-small cell lung carcinoma missense_variant 1.887% (1/53) 1 entry
ENSG00000072274 ovarian serous adenocarcinoma sequence_alteration 0.7429% (5/673) 1 entry
ENSG00000072274 primary peritoneal carcinoma (disease) sequence_alteration 100.0% (1/1) 1 entry
ENSG00000072274 basal cell carcinoma missense_variant 3.448% (2/58) 1 entry
ENSG00000072274 clear cell renal carcinoma sequence_alteration 0.3628% (5/1378) 1 entry
ENSG00000072274 basal cell carcinoma sequence_alteration 3.448% (2/58) 1 entry
ENSG00000072274 oral squamous cell carcinoma missense_variant 0.4878% (1/205) 1 entry
ENSG00000072274 bladder transitional cell carcinoma missense_variant 0.7299% (1/137) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000072274 MESO 0.0057 high
ENSG00000072274 SARC 0.02 high
ENSG00000072274 STAD 0.027 low
ENSG00000072274 UVM 0.032 high
ENSG00000072274 PAAD 0.0011 high
ENSG00000072274 UCEC 0.014 high
ENSG00000072274 THCA 0.00026 high
ENSG00000072274 ACC 0.0012 high
ENSG00000072274 LUSC 0.0093 low
ENSG00000072274 HNSC 0.0061 high
ENSG00000072274 READ 0.013 low
ENSG00000072274 KIRP 0.00051 high
ENSG00000072274 BRCA 0.0021 high
ENSG00000072274 OV 0.022 high
ENSG00000072274 TGCT 0.012 high
ENSG00000072274 BLCA 0.008 high
ENSG00000072274 LAML 0.05 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000072274 LUSC Amp 108.802275 1.432331 1.135662 0.880240
ENSG00000072274 LUAD Amp 1.784570 0.144591 0.448604 0.267442
ENSG00000072274 LUAD Del 1.461249 0.061476 0.331667 0.259690
ENSG00000072274 LGG Del 3.824938 0.066901 0.527057 0.089669
ENSG00000072274 CESC Amp 27.921881 0.675335 1.073535 0.752542
ENSG00000072274 UCS Amp 2.327463 0.738222 0.991714 0.571429
ENSG00000072274 SARC Del 1.266138 0.138596 0.512229 0.202335
ENSG00000072274 GBM Amp 0.879024 0.070544 0.430714 0.138648
ENSG00000072274 GBM Del 3.293403 0.079182 0.501107 0.105719
ENSG00000072274 ESCA Amp 14.812807 0.836096 0.931253 0.652174
ENSG00000072274 HNSC Amp 40.476981 0.608972 0.776339 0.716475
ENSG00000072274 LIHC Amp 1.723733 0.139732 0.533303 0.172973
ENSG00000072274 PCPG Del 2.483091 0.093562 0.634802 0.580247
ENSG00000072274 TGCT Amp 1.156308 0.138857 0.462811 0.293333
ENSG00000072274 DLBC Amp 2.314444 0.360896 0.811921 0.312500
ENSG00000072274 BLCA Amp 1.740199 0.201418 0.508472 0.524510
ENSG00000072274 BRCA Amp 6.253846 0.226372 0.571014 0.296296
ENSG00000072274 STAD Amp 4.823566 0.233872 0.492273 0.340136
ENSG00000072274 UCEC Amp 23.853435 0.392103 0.864527 0.280148
ENSG00000072274 KIRC Amp 1.802912 0.045776 0.390757 0.159091
ENSG00000072274 OV Amp 48.215627 1.020833 0.988124 0.711572