Ensembl ID ENSG00000071894 Gene ID 29894 Accession 2324
Gene Symbol CPSF1 Alias MYP27;CPSF160;P/cl.18;HSU37012 Full Name cleavage and polyadenylation specific factor 1
Position 8 : 144393229 - 144409335 Length 16107 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]

ENSG00000071894 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000071894 CPSF1 0.53 1.23e-14 KIRC
ENSG00000071894 CPSF1 0.62 1.20e-14 HNSC
ENSG00000071894 CPSF1 0.80 1.14e-29 BRCA
ENSG00000071894 CPSF1 0.85 2.23e-11 COAD
ENSG00000071894 CPSF1 0.74 4.41e-16 LUSC
ENSG00000071894 CPSF1 0.83 1.11e-17 LIHC
ENSG00000071894 CPSF1 0.88 3.62e-12 UCEC
ENSG00000071894 CPSF1 0.90 4.49e-21 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000071894 CPSF1 lung cancer 28634396
ENSG00000071894 CPSF1 ovarian cancer 29358555
ENSG00000071894 CPSF1 prostate cancer 30775247
ENSG00000071894 CPSF1 breast cancer 31646075
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000071894 CPSF1 MESO 0.0052 high
ENSG00000071894 CPSF1 UVM 0.0031 high
ENSG00000071894 CPSF1 PAAD 0.0031 low
ENSG00000071894 CPSF1 LGG 0.023 high
ENSG00000071894 CPSF1 KIRP 0.029 high
ENSG00000071894 CPSF1 THYM 0.00094 low
ENSG00000071894 CPSF1 BRCA 0.031 low
ENSG00000071894 CPSF1 COAD 0.007 high
ENSG00000071894 CPSF1 ESCA 0.016 high
ENSG00000071894 CPSF1 DLBC 0.016 high
ENSG00000071894 CPSF1 BLCA 0.0057 low
ENSG00000071894 CPSF1 LIHC 0.0017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency