Ensembl ID
ENSG00000071794
Gene ID
6596
Accession
11099
Gene Symbol
HLTF
Alias
ZBU1;HLTF1;RNF80;HIP116;SNF2L3;HIP116A;SMARCA3
Full Name
helicase like transcription factor
Position
3 : 149030127 - 149086554
Length
56428 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]
ENSG00000071794 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000071794
HLTF
-0.5
2.46e-14
KIRC
ENSG00000071794
HLTF
1.20
4.15e-15
HNSC
ENSG00000071794
HLTF
0.53
1.07e-14
BRCA
ENSG00000071794
HLTF
1.36
3.39e-31
LUSC
ENSG00000071794
HLTF
0.93
7.18e-21
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000071794
HLTF
colon cancer
11904375
ENSG00000071794
HLTF
cancers
12584739
ENSG00000071794
HLTF
gastric cancer
12766908
ENSG00000071794
HLTF
tumor
12901794
ENSG00000071794
HLTF
colonic cancers
15386372
ENSG00000071794
HLTF
colorectal cancers
15793636
ENSG00000071794
HLTF
cancer
16181380
ENSG00000071794
HLTF
tumor
16331610
ENSG00000071794
HLTF
tumor
16475210
ENSG00000071794
HLTF
colorectal cancers
16475679
ENSG00000071794
HLTF
gastric cancer
16497821
ENSG00000071794
HLTF
colon cancer
16708352
ENSG00000071794
HLTF
cancer
16762066
ENSG00000071794
HLTF
tumor
17189406
ENSG00000071794
HLTF
colorectal cancers
17201142
ENSG00000071794
HLTF
tumor
17378912
ENSG00000071794
HLTF
cervical cancer
17578348
ENSG00000071794
HLTF
colorectal cancer
17657744
ENSG00000071794
HLTF
cancer
18034322
ENSG00000071794
HLTF
gastric cancers
18316726
ENSG00000071794
HLTF
tumor
18825407
ENSG00000071794
HLTF
colorectal cancer
19282772
ENSG00000071794
HLTF
HNSCC
19614770
ENSG00000071794
HLTF
cancer
19723507
ENSG00000071794
HLTF
colorectal cancer
19773381
ENSG00000071794
HLTF
tumor
19948885
ENSG00000071794
HLTF
cancer
20388495
ENSG00000071794
HLTF
cervical cancer
20535496
ENSG00000071794
HLTF
colorectal cancer
20552891
ENSG00000071794
HLTF
lung tumors
20849603
ENSG00000071794
HLTF
colorectal cancers
21326223
ENSG00000071794
HLTF
colorectal cancer
21479407
ENSG00000071794
HLTF
tumor
21531217
ENSG00000071794
HLTF
tumor
22362391
ENSG00000071794
HLTF
colon cancers
22452792
ENSG00000071794
HLTF
tumor
22766745
ENSG00000071794
HLTF
bladder cancer
23485510
ENSG00000071794
HLTF
tumor
23826137
ENSG00000071794
HLTF
tumour
24198246
ENSG00000071794
HLTF
bladder cancer
24577895
ENSG00000071794
HLTF
tumors
24708595
ENSG00000071794
HLTF
thyroid tumor
25005870
ENSG00000071794
HLTF
tumors
25841351
ENSG00000071794
HLTF
tumor
25906194
ENSG00000071794
HLTF
tumour
26350214
ENSG00000071794
HLTF
gallbladder cancer
26456195
ENSG00000071794
HLTF
cancer
26472339
ENSG00000071794
HLTF
tumor
26802049
ENSG00000071794
HLTF
cancer
27308329
ENSG00000071794
HLTF
tumors
27379156
ENSG00000071794
HLTF
colorectal cancer
27844020
ENSG00000071794
HLTF
tumor
28187169
ENSG00000071794
HLTF
Tumor
28451061
ENSG00000071794
HLTF
cancer
28954549
ENSG00000071794
HLTF
cancer
28981387
ENSG00000071794
HLTF
tumour
29038612
ENSG00000071794
HLTF
colorectal cancer
29564023
ENSG00000071794
HLTF
tumor
29661164
ENSG00000071794
HLTF
cancers
29807746
ENSG00000071794
HLTF
cancer
29955035
ENSG00000071794
HLTF
tumor
29975766
ENSG00000071794
HLTF
cancer
30232006
ENSG00000071794
HLTF
colorectal cancer
30320371
ENSG00000071794
HLTF
tumor
30528265
ENSG00000071794
HLTF
colonic cancers
30657113
ENSG00000071794
HLTF
acute myeloid leukemia (AML)
30696947
ENSG00000071794
HLTF
tumor
31350889
ENSG00000071794
HLTF
cancer
31429594
ENSG00000071794
HLTF
colorectal tumors
31461471
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000071794
HLTF
UVM
0.014
low
show
ENSG00000071794
HLTF
PAAD
0.044
low
show
ENSG00000071794
HLTF
UCEC
0.0017
high
show
ENSG00000071794
HLTF
THCA
0.0081
high
show
ENSG00000071794
HLTF
ACC
0.044
high
show
ENSG00000071794
HLTF
LUSC
0.043
high
show
ENSG00000071794
HLTF
HNSC
0.0086
high
show
ENSG00000071794
HLTF
KIRP
0.027
low
show
ENSG00000071794
HLTF
PCPG
0.017
high
show
ENSG00000071794
HLTF
THYM
0.05
high
show
ENSG00000071794
HLTF
BRCA
0.04
high
show
ENSG00000071794
HLTF
KIRC
0.032
low
show
ENSG00000071794
HLTF
BLCA
0.023
low
show
ENSG00000071794
HLTF
LAML
0.011
low
show
ENSG00000071794
HLTF
SKCM
0.0014
low
show
ENSG00000071794
HLTF
CESC
0.048
low
show
ENSG00000071794
HLTF
LIHC
0.0021
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000071794
HLTF
LUSC
Amp
43.540222
0.822602
0.940651
0.832335
ENSG00000071794
HLTF
CESC
Amp
11.139763
0.390470
0.966546
0.701695
ENSG00000071794
HLTF
ESCA
Amp
5.530083
0.497953
0.796147
0.603261
ENSG00000071794
HLTF
HNSC
Amp
21.046402
0.411499
0.726550
0.666667
ENSG00000071794
HLTF
PCPG
Del
1.375954
0.072845
0.629463
0.574074
ENSG00000071794
HLTF
BRCA
Amp
0.785514
0.147134
0.515857
0.275000
ENSG00000071794
HLTF
PRAD
Amp
1.557206
0.058026
0.432389
0.144309
ENSG00000071794
HLTF
UCEC
Amp
4.132854
0.169342
0.659149
0.233766
ENSG00000071794
HLTF
OV
Amp
18.306508
0.672732
0.863838
0.682211
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