Ensembl ID ENSG00000069275 Gene ID 64710 Accession 29923
Gene Symbol NUCKS1 Alias JC7;NUCKS Full Name nuclear casein kinase and cyclin dependent kinase substrate 1
Position 1 : 205712822 - 205750182 Length 37361 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010]

ENSG00000069275 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000069275 NUCKS1 -0.3 2.17e-11 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000069275 NUCKS1 breast cancer 18491381
ENSG00000069275 NUCKS1 breast cancer 19664271
ENSG00000069275 NUCKS1 breast cancer 20069058
ENSG00000069275 NUCKS1 colorectal cancer 23065711
ENSG00000069275 NUCKS1 cancer 24140890
ENSG00000069275 NUCKS1 tumor 24284105
ENSG00000069275 NUCKS1 breast cancer 24568505
ENSG00000069275 NUCKS1 tumour 24819170
ENSG00000069275 NUCKS1 cancers 25116364
ENSG00000069275 NUCKS1 skin tumors 25119009
ENSG00000069275 NUCKS1 breast cancer 25187794
ENSG00000069275 NUCKS1 cancer 25760963
ENSG00000069275 NUCKS1 cancer 26323318
ENSG00000069275 NUCKS1 endometrial cancer 26885454
ENSG00000069275 NUCKS1 tumor 26968889
ENSG00000069275 NUCKS1 lung cancer 26989074
ENSG00000069275 NUCKS1 tumor 27542204
ENSG00000069275 NUCKS1 lung cancer 28592245
ENSG00000069275 NUCKS1 ovarian cancer 28877654
ENSG00000069275 NUCKS1 tumors 29619377
ENSG00000069275 NUCKS1 gastric cancer 30371738
ENSG00000069275 NUCKS1 tumors 30847170
ENSG00000069275 NUCKS1 pancreatic cancer 31914803
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000069275 NUCKS1 MESO 5e-04 high
ENSG00000069275 NUCKS1 SARC 0.012 high
ENSG00000069275 NUCKS1 STAD 0.0044 high
ENSG00000069275 NUCKS1 PAAD 0.001 high
ENSG00000069275 NUCKS1 UCEC 0.00033 high
ENSG00000069275 NUCKS1 THCA 0.021 high
ENSG00000069275 NUCKS1 ACC 0.023 high
ENSG00000069275 NUCKS1 LGG 0.0065 low
ENSG00000069275 NUCKS1 READ 0.026 high
ENSG00000069275 NUCKS1 KIRP 0.00085 high
ENSG00000069275 NUCKS1 KICH 0.016 high
ENSG00000069275 NUCKS1 LUAD 0.022 high
ENSG00000069275 NUCKS1 PCPG 0.0011 high
ENSG00000069275 NUCKS1 THYM 0.024 low
ENSG00000069275 NUCKS1 UCS 0.0035 low
ENSG00000069275 NUCKS1 OV 0.0056 low
ENSG00000069275 NUCKS1 KIRC 0.00011 low
ENSG00000069275 NUCKS1 BLCA 0.0086 high
ENSG00000069275 NUCKS1 SKCM 0.0011 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000069275 NUCKS1 LUAD Amp 1.210954 0.130877 0.502576 0.709302
ENSG00000069275 NUCKS1 SARC Del 2.278994 0.163451 0.453701 0.284047
ENSG00000069275 NUCKS1 SKCM Amp 3.071865 0.191611 0.711790 0.544959
ENSG00000069275 NUCKS1 LIHC Amp 5.532111 0.216497 0.861099 0.727027
ENSG00000069275 NUCKS1 BRCA Amp 16.049466 0.318109 0.811851 0.760185
ENSG00000069275 NUCKS1 UCEC Amp 3.011677 0.151319 0.857774 0.426716