Ensembl ID
ENSG00000069275
Gene ID
64710
Accession
29923
Gene Symbol
NUCKS1
Alias
JC7;NUCKS
Full Name
nuclear casein kinase and cyclin dependent kinase substrate 1
Position
1 : 205712822 - 205750182
Length
37361 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010]
ENSG00000069275 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000069275
NUCKS1
-0.3
2.17e-11
KIRC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000069275
NUCKS1
breast cancer
18491381
ENSG00000069275
NUCKS1
breast cancer
19664271
ENSG00000069275
NUCKS1
breast cancer
20069058
ENSG00000069275
NUCKS1
colorectal cancer
23065711
ENSG00000069275
NUCKS1
cancer
24140890
ENSG00000069275
NUCKS1
tumor
24284105
ENSG00000069275
NUCKS1
breast cancer
24568505
ENSG00000069275
NUCKS1
tumour
24819170
ENSG00000069275
NUCKS1
cancers
25116364
ENSG00000069275
NUCKS1
skin tumors
25119009
ENSG00000069275
NUCKS1
breast cancer
25187794
ENSG00000069275
NUCKS1
cancer
25760963
ENSG00000069275
NUCKS1
cancer
26323318
ENSG00000069275
NUCKS1
endometrial cancer
26885454
ENSG00000069275
NUCKS1
tumor
26968889
ENSG00000069275
NUCKS1
lung cancer
26989074
ENSG00000069275
NUCKS1
tumor
27542204
ENSG00000069275
NUCKS1
lung cancer
28592245
ENSG00000069275
NUCKS1
ovarian cancer
28877654
ENSG00000069275
NUCKS1
tumors
29619377
ENSG00000069275
NUCKS1
gastric cancer
30371738
ENSG00000069275
NUCKS1
tumors
30847170
ENSG00000069275
NUCKS1
pancreatic cancer
31914803
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000069275
NUCKS1
MESO
5e-04
high
show
ENSG00000069275
NUCKS1
SARC
0.012
high
show
ENSG00000069275
NUCKS1
STAD
0.0044
high
show
ENSG00000069275
NUCKS1
PAAD
0.001
high
show
ENSG00000069275
NUCKS1
UCEC
0.00033
high
show
ENSG00000069275
NUCKS1
THCA
0.021
high
show
ENSG00000069275
NUCKS1
ACC
0.023
high
show
ENSG00000069275
NUCKS1
LGG
0.0065
low
show
ENSG00000069275
NUCKS1
READ
0.026
high
show
ENSG00000069275
NUCKS1
KIRP
0.00085
high
show
ENSG00000069275
NUCKS1
KICH
0.016
high
show
ENSG00000069275
NUCKS1
LUAD
0.022
high
show
ENSG00000069275
NUCKS1
PCPG
0.0011
high
show
ENSG00000069275
NUCKS1
THYM
0.024
low
show
ENSG00000069275
NUCKS1
UCS
0.0035
low
show
ENSG00000069275
NUCKS1
OV
0.0056
low
show
ENSG00000069275
NUCKS1
KIRC
0.00011
low
show
ENSG00000069275
NUCKS1
BLCA
0.0086
high
show
ENSG00000069275
NUCKS1
SKCM
0.0011
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000069275
NUCKS1
LUAD
Amp
1.210954
0.130877
0.502576
0.709302
ENSG00000069275
NUCKS1
SARC
Del
2.278994
0.163451
0.453701
0.284047
ENSG00000069275
NUCKS1
SKCM
Amp
3.071865
0.191611
0.711790
0.544959
ENSG00000069275
NUCKS1
LIHC
Amp
5.532111
0.216497
0.861099
0.727027
ENSG00000069275
NUCKS1
BRCA
Amp
16.049466
0.318109
0.811851
0.760185
ENSG00000069275
NUCKS1
UCEC
Amp
3.011677
0.151319
0.857774
0.426716
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