Ensembl ID ENSG00000068654 Gene ID 25885 Accession 17264
Gene Symbol POLR1A Alias A190;RPA1;RPO14;AFDCIN;RPA190;RPA194;RPO1-4 Full Name RNA polymerase I subunit A
Position 2 : 86020216 - 86106155 Length 85940 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016]

ENSG00000068654 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000068654 POLR1A 0.43 1.86e-19 BRCA
ENSG00000068654 POLR1A 0.79 3.73e-27 COAD
ENSG00000068654 POLR1A 0.71 1.00e-17 LUSC
ENSG00000068654 POLR1A 0.80 4.04e-29 LIHC
ENSG00000068654 POLR1A 0.68 5.52e-14 STAD
ENSG00000068654 POLR1A 0.49 2.56e-11 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000068654 POLR1A cancer 21399665
ENSG00000068654 POLR1A tumour 21418567
ENSG00000068654 POLR1A cancer 21878508
ENSG00000068654 POLR1A cancer 24434211
ENSG00000068654 POLR1A cancer 24847734
ENSG00000068654 POLR1A cancer 25482194
ENSG00000068654 POLR1A Tumour 26333121
ENSG00000068654 POLR1A cancer 29642000
ENSG00000068654 POLR1A cancer 30888702
ENSG00000068654 POLR1A tumors 30936423
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000068654 POLR1A MESO 0.029 high
ENSG00000068654 POLR1A STAD 0.002 low
ENSG00000068654 POLR1A PAAD 0.04 low
ENSG00000068654 POLR1A UCEC 0.028 high
ENSG00000068654 POLR1A THCA 0.00087 high
ENSG00000068654 POLR1A READ 0.0065 low
ENSG00000068654 POLR1A KIRP 0.0033 high
ENSG00000068654 POLR1A KICH 0.00032 high
ENSG00000068654 POLR1A LUAD 0.0058 high
ENSG00000068654 POLR1A PCPG 0.043 low
ENSG00000068654 POLR1A BRCA 0.015 high
ENSG00000068654 POLR1A UCS 0.049 high
ENSG00000068654 POLR1A OV 0.00022 high
ENSG00000068654 POLR1A PRAD 0.026 high
ENSG00000068654 POLR1A BLCA 0.032 high
ENSG00000068654 POLR1A SKCM 0.00014 high
ENSG00000068654 POLR1A CESC 0.014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency