Ensembl ID
ENSG00000065613
Gene ID
9748
Accession
11088
Gene Symbol
SLK
Alias
LOSK;STK2;se20-9;bA16H23.1
Full Name
STE20 like kinase
Position
10 : 103967140 - 104029233
Length
62094 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
Enables protein homodimerization activity and protein serine/threonine kinase activity. Involved in several processes, including cytoplasmic microtubule organization; protein autophosphorylation; and regulation of focal adhesion assembly. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000065613 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000065613
SLK
-0.8
2.21e-15
HNSC
ENSG00000065613
SLK
-0.4
1.56e-18
BRCA
ENSG00000065613
SLK
-1.0
3.23e-18
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000065613
SLK
tumor
23594797
ENSG00000065613
SLK
tumor
26657153
ENSG00000065613
SLK
lung cancer
29339539
ENSG00000065613
SLK
cancer
30320378
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000065613
SLK
SARC
0.047
high
show
ENSG00000065613
SLK
CHOL
0.0044
low
show
ENSG00000065613
SLK
THCA
0.03
high
show
ENSG00000065613
SLK
ACC
0.012
high
show
ENSG00000065613
SLK
LGG
0.01
low
show
ENSG00000065613
SLK
LUSC
0.043
low
show
ENSG00000065613
SLK
READ
0.025
low
show
ENSG00000065613
SLK
KIRP
0.032
low
show
ENSG00000065613
SLK
LUAD
0.0029
high
show
ENSG00000065613
SLK
PCPG
0.035
low
show
ENSG00000065613
SLK
PRAD
0.037
low
show
ENSG00000065613
SLK
GBM
0.049
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000065613
SLK
LUSC
Del
1.866000
0.081469
0.362560
0.522954
ENSG00000065613
SLK
LGG
Del
4.192009
0.069433
0.572623
0.235867
ENSG00000065613
SLK
CESC
Del
0.825678
0.069363
0.442056
0.301695
ENSG00000065613
SLK
READ
Del
0.723532
0.072833
0.414147
0.303030
ENSG00000065613
SLK
COAD
Del
8.044924
0.101063
0.395403
0.241685
ENSG00000065613
SLK
GBM
Del
0.825836
0.053476
0.697312
0.885615
ENSG00000065613
SLK
LIHC
Del
1.376618
0.076663
0.483707
0.264865
ENSG00000065613
SLK
BLCA
Del
1.288445
0.087302
0.395569
0.409314
ENSG00000065613
SLK
BRCA
Del
6.782037
0.101248
0.388677
0.305556
ENSG00000065613
SLK
STAD
Del
1.830976
0.076350
0.358885
0.224490
ENSG00000065613
SLK
PRAD
Del
3.073671
0.098803
0.443536
0.160569
ENSG00000065613
SLK
UCEC
Del
3.509223
0.076930
0.544291
0.126160
ENSG00000065613
SLK
MESO
Del
2.562923
0.196619
0.482687
0.356322
ENSG00000065613
SLK
OV
Del
12.140008
0.319559
0.565450
0.414508
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.