Ensembl ID ENSG00000065243 Gene ID 5586 Accession 9406
Gene Symbol PKN2 Alias PAK2;PRK2;STK7;Pak-2;PRKCL2;PRO2042 Full Name protein kinase N2
Position 1 : 88684222 - 88836255 Length 152034 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Enables RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including apical junction assembly; positive regulation of cell cycle; and positive regulation of viral genome replication. Located in several cellular components, including cleavage furrow; cytoskeleton; and midbody. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000065243 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000065243 -0.4 1.41e-18 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000065243 tumour 21754995
ENSG00000065243 tumors 22511072
ENSG00000065243 cancer 26041307
ENSG00000065243 prostate cancer 26296974
ENSG00000065243 tumour 27919031
ENSG00000065243 breast cancer 28515445
ENSG00000065243 prostate cancer 28875501
ENSG00000065243 tumor 29368606
ENSG00000065243 head and neck cancer 29480433
ENSG00000065243 bladder cancer 31420610
ENSG00000065243 tumor 31759986
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000065243 SARC 0.021 high
ENSG00000065243 CHOL 0.038 low
ENSG00000065243 UVM 0.0034 high
ENSG00000065243 PAAD 0.0043 high
ENSG00000065243 UCEC 0.046 high
ENSG00000065243 THCA 0.0086 high
ENSG00000065243 HNSC 0.012 low
ENSG00000065243 READ 0.024 low
ENSG00000065243 KICH 0.0095 high
ENSG00000065243 PCPG 0.048 low
ENSG00000065243 COAD 0.00022 low
ENSG00000065243 OV 0.017 low
ENSG00000065243 DLBC 0.041 high
ENSG00000065243 LAML 0.0084 low
ENSG00000065243 GBM 0.022 low
ENSG00000065243 LIHC 0.0017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000065243 LUAD Del 4.329745 0.087703 0.323892 0.275194
ENSG00000065243 READ Del 0.782848 0.074801 0.407942 0.345455
ENSG00000065243 COAD Del 2.725837 0.062895 0.412759 0.283814
ENSG00000065243 SKCM Del 3.793072 0.109150 0.440410 0.245232
ENSG00000065243 HNSC Del 1.606109 0.064503 0.347518 0.178161
ENSG00000065243 PCPG Del 12.729895 0.218535 0.682676 0.746914
ENSG00000065243 BRCA Del 5.704342 0.096135 0.401807 0.325926
ENSG00000065243 STAD Del 1.779979 0.075859 0.351475 0.224490
ENSG00000065243 MESO Del 7.091506 0.323551 0.558133 0.379310