Ensembl ID
ENSG00000064703
Gene ID
11218
Accession
2743
Gene Symbol
DDX20
Alias
DP103;GEMIN3
Full Name
DEAD-box helicase 20
Position
1 : 111754832 - 111775602
Length
20771 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Canonical_RBPs
Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]
ENSG00000064703 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000064703
DDX20
tumor
16822855
ENSG00000064703
DDX20
bladder cancer
18381463
ENSG00000064703
DDX20
lung cancer
20721975
ENSG00000064703
DDX20
liver tumor
22445758
ENSG00000064703
DDX20
liver tumor
22898998
ENSG00000064703
DDX20
breast cancer
23629745
ENSG00000064703
DDX20
breast cancers
25083991
ENSG00000064703
DDX20
cancer
25709475
ENSG00000064703
DDX20
gastric cancer
25784816
ENSG00000064703
DDX20
cancer
26203264
ENSG00000064703
DDX20
breast cancer
27121695
ENSG00000064703
DDX20
breast cancer
27232533
ENSG00000064703
DDX20
cancer
27308465
ENSG00000064703
DDX20
cancer
28823267
ENSG00000064703
DDX20
colorectal cancer
29844832
ENSG00000064703
DDX20
tumor
31510013
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000064703
DDX20
MESO
0.0013
low
show
ENSG00000064703
DDX20
SARC
0.019
high
show
ENSG00000064703
DDX20
STAD
0.029
low
show
ENSG00000064703
DDX20
CHOL
0.017
low
show
ENSG00000064703
DDX20
ACC
0.0019
high
show
ENSG00000064703
DDX20
LUSC
0.0095
low
show
ENSG00000064703
DDX20
HNSC
0.023
low
show
ENSG00000064703
DDX20
KICH
0.00045
high
show
ENSG00000064703
DDX20
PCPG
0.014
high
show
ENSG00000064703
DDX20
THYM
0.031
low
show
ENSG00000064703
DDX20
BRCA
0.014
low
show
ENSG00000064703
DDX20
COAD
0.0014
low
show
ENSG00000064703
DDX20
OV
0.0062
low
show
ENSG00000064703
DDX20
KIRC
0.00013
low
show
ENSG00000064703
DDX20
PRAD
0.028
high
show
ENSG00000064703
DDX20
BLCA
0.034
low
show
ENSG00000064703
DDX20
GBM
0.018
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000064703
DDX20
LUSC
Del
9.196315
0.145002
0.397730
0.443114
ENSG00000064703
DDX20
LUAD
Del
11.457107
0.136171
0.353840
0.302326
ENSG00000064703
DDX20
CESC
Del
1.392852
0.080740
0.435379
0.108475
ENSG00000064703
DDX20
READ
Del
0.807303
0.075457
0.398297
0.333333
ENSG00000064703
DDX20
COAD
Del
2.874944
0.064095
0.419071
0.270510
ENSG00000064703
DDX20
SARC
Del
0.636684
0.117533
0.585893
0.171206
ENSG00000064703
DDX20
ESCA
Del
1.992532
0.132978
0.391474
0.326087
ENSG00000064703
DDX20
SKCM
Del
3.621123
0.107085
0.430887
0.220708
ENSG00000064703
DDX20
HNSC
Del
13.140654
0.138131
0.396818
0.241379
ENSG00000064703
DDX20
PCPG
Del
17.215344
0.263979
0.695032
0.740741
ENSG00000064703
DDX20
BRCA
Del
7.016540
0.102351
0.395249
0.296296
ENSG00000064703
DDX20
STAD
Del
1.266767
0.068740
0.354077
0.215420
ENSG00000064703
DDX20
MESO
Del
7.760707
0.340973
0.576590
0.379310
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