Ensembl ID ENSG00000063046 Gene ID 1975 Accession 3285
Gene Symbol EIF4B Alias EIF-4B;PRO1843 Full Name eukaryotic translation initiation factor 4B
Position 12 : 53006431 - 53042215 Length 35785 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables RNA binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Located in cytosol. Biomarker of autism spectrum disorder and major depressive disorder. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000063046 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000063046 EIF4B -0.6 1.95e-19 HNSC
ENSG00000063046 EIF4B -0.8 3.94e-11 BLCA
ENSG00000063046 EIF4B -0.5 3.81e-31 BRCA
ENSG00000063046 EIF4B -1.0 1.63e-25 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000063046 EIF4B cancer 20145189
ENSG00000063046 EIF4B cancer 20948310
ENSG00000063046 EIF4B tumor 22871496
ENSG00000063046 EIF4B cancers 23749639
ENSG00000063046 EIF4B tumor 23776612
ENSG00000063046 EIF4B DLBCL 24135829
ENSG00000063046 EIF4B triple-negative breast cancer 25129346
ENSG00000063046 EIF4B tumors 25611378
ENSG00000063046 EIF4B cancers 25776026
ENSG00000063046 EIF4B Tumors 26498689
ENSG00000063046 EIF4B tumour 26729235
ENSG00000063046 EIF4B cancers 26848623
ENSG00000063046 EIF4B breast cancer 27028868
ENSG00000063046 EIF4B GBM 27120806
ENSG00000063046 EIF4B tumor 27528663
ENSG00000063046 EIF4B colon cancer 27773818
ENSG00000063046 EIF4B AML 27870639
ENSG00000063046 EIF4B breast cancer 27926932
ENSG00000063046 EIF4B Cancer 28697756
ENSG00000063046 EIF4B prostate cancer 29124675
ENSG00000063046 EIF4B tumor 29416735
ENSG00000063046 EIF4B DLBCLs 29483509
ENSG00000063046 EIF4B granulosa cell tumors 29549247
ENSG00000063046 EIF4B cancer 30228356
ENSG00000063046 EIF4B cancer 30686754
ENSG00000063046 EIF4B skin cancer 31040906
ENSG00000063046 EIF4B breast cancer 31106142
ENSG00000063046 EIF4B breast cancer 31496730
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000063046 EIF4B MESO 0.023 low
ENSG00000063046 EIF4B HNSC 0.021 high
ENSG00000063046 EIF4B READ 0.017 low
ENSG00000063046 EIF4B KIRP 0.026 high
ENSG00000063046 EIF4B LUAD 0.018 high
ENSG00000063046 EIF4B THYM 0.047 low
ENSG00000063046 EIF4B BRCA 0.034 high
ENSG00000063046 EIF4B UCS 0.0054 low
ENSG00000063046 EIF4B OV 0.014 high
ENSG00000063046 EIF4B DLBC 0.012 high
ENSG00000063046 EIF4B BLCA 0.0054 high
ENSG00000063046 EIF4B CESC 0.017 high
ENSG00000063046 EIF4B LIHC 0.002 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency