Ensembl ID ENSG00000059588 Gene ID 6894 Accession 11568
Gene Symbol TARBP1 Alias TRM3;TRMT3;TRP185;TRP-185 Full Name TAR (HIV-1) RNA binding protein 1
Position 1 : 234391313 - 234479179 Length 87867 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

ENSG00000059588 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000059588 TARBP1 0.71 1.02e-22 BRCA
ENSG00000059588 TARBP1 1.26 3.25e-34 COAD
ENSG00000059588 TARBP1 1.38 6.89e-16 READ
ENSG00000059588 TARBP1 1.20 1.00e-34 LUSC
ENSG00000059588 TARBP1 1.00 3.53e-27 PRAD
ENSG00000059588 TARBP1 1.77 3.55e-51 LIHC
ENSG00000059588 TARBP1 1.12 3.94e-21 STAD
ENSG00000059588 TARBP1 0.85 2.17e-17 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000059588 TARBP1 skin cancer 22025453
ENSG00000059588 TARBP1 tumor 26464651
ENSG00000059588 TARBP1 cancer 27040643
ENSG00000059588 TARBP1 non-small-cell lung cancer 29731880
ENSG00000059588 TARBP1 cancers 31957540
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000059588 TARBP1 SARC 0.0032 high
ENSG00000059588 TARBP1 STAD 0.033 low
ENSG00000059588 TARBP1 PAAD 0.003 low
ENSG00000059588 TARBP1 ACC 0.003 high
ENSG00000059588 TARBP1 LGG 0.014 low
ENSG00000059588 TARBP1 LUSC 0.011 low
ENSG00000059588 TARBP1 HNSC 0.0029 low
ENSG00000059588 TARBP1 READ 0.017 low
ENSG00000059588 TARBP1 KIRP 0.016 high
ENSG00000059588 TARBP1 LUAD 0.041 low
ENSG00000059588 TARBP1 PCPG 0.014 high
ENSG00000059588 TARBP1 BRCA 0.0036 low
ENSG00000059588 TARBP1 OV 0.03 low
ENSG00000059588 TARBP1 DLBC 0.0014 high
ENSG00000059588 TARBP1 BLCA 0.049 high
ENSG00000059588 TARBP1 LAML 0.029 low
ENSG00000059588 TARBP1 SKCM 0.0043 low
ENSG00000059588 TARBP1 LIHC 0.014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000059588 TARBP1 SARC Del 6.254631 0.237593 0.491333 0.346304
ENSG00000059588 TARBP1 SKCM Amp 2.251285 0.168591 0.697133 0.525886
ENSG00000059588 TARBP1 LIHC Amp 6.904916 0.240402 0.864513 0.718919
ENSG00000059588 TARBP1 DLBC Del 1.204788 0.151120 0.560453 0.145833
ENSG00000059588 TARBP1 BRCA Amp 16.462492 0.321483 0.812724 0.740741
ENSG00000059588 TARBP1 STAD Amp 2.700198 0.187250 0.568229 0.317460
ENSG00000059588 TARBP1 PRAD Del 3.559675 0.103204 0.531434 0.095528
ENSG00000059588 TARBP1 UCEC Amp 3.298305 0.155876 0.870950 0.415584
ENSG00000059588 TARBP1 OV Amp 12.068846 0.581280 0.778854 0.559585