Ensembl ID ENSG00000058262 Gene ID 29927 Accession 18276
Gene Symbol SEC61A1 Alias HNFJ4;SEC61;ADTKD5;HSEC61;SEC61A Full Name SEC61 translocon subunit alpha 1
Position 3 : 128051641 - 128071705 Length 20065 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

ENSG00000058262 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000058262 SEC61A1 0.72 5.42e-13 BLCA
ENSG00000058262 SEC61A1 0.62 1.49e-39 BRCA
ENSG00000058262 SEC61A1 0.96 4.67e-25 KICH
ENSG00000058262 SEC61A1 0.68 1.23e-24 LUSC
ENSG00000058262 SEC61A1 1.57 1.00e-16 GBM
ENSG00000058262 SEC61A1 0.91 1.36e-28 UCEC
ENSG00000058262 SEC61A1 0.65 2.15e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000058262 SEC61A1 MESO 0.0027 high
ENSG00000058262 SEC61A1 SARC 0.00041 high
ENSG00000058262 SEC61A1 STAD 0.025 low
ENSG00000058262 SEC61A1 UVM 0.023 low
ENSG00000058262 SEC61A1 PAAD 0.032 high
ENSG00000058262 SEC61A1 UCEC 0.00077 low
ENSG00000058262 SEC61A1 ACC 0.0073 high
ENSG00000058262 SEC61A1 READ 0.049 low
ENSG00000058262 SEC61A1 KICH 0.0013 high
ENSG00000058262 SEC61A1 LUAD 0.013 high
ENSG00000058262 SEC61A1 ESCA 0.012 high
ENSG00000058262 SEC61A1 OV 0.033 low
ENSG00000058262 SEC61A1 TGCT 0.00095 low
ENSG00000058262 SEC61A1 BLCA 0.025 high
ENSG00000058262 SEC61A1 GBM 0.029 high
ENSG00000058262 SEC61A1 SKCM 0.0024 high
ENSG00000058262 SEC61A1 CESC 0.013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000058262 SEC61A1 GBM Del 1.004317 0.055915 0.480234 0.093588
ENSG00000058262 SEC61A1 PRAD Amp 2.979298 0.076723 0.449309 0.150407