Ensembl ID ENSG00000057608 Gene ID 2665 Accession 4227
Gene Symbol GDI2 Alias RABGDIB;HEL-S-46e Full Name GDP dissociation inhibitor 2
Position 10 : 5765223 - 5842132 Length 76910 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

ENSG00000057608 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000057608 0.33 6.75e-11 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000057608 pancreatic cancer 17507299
ENSG00000057608 ovarian cancer 20858016
ENSG00000057608 breast cancer 23792445
ENSG00000057608 gastric cancer 24185104
ENSG00000057608 tumor 24615502
ENSG00000057608 gastric cancer 24721928
ENSG00000057608 tumor 25059231
ENSG00000057608 tumor 25367783
ENSG00000057608 ovarian cancer 28857608
ENSG00000057608 cancer 28916862
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000057608 MESO 0.0021 low
ENSG00000057608 SARC 0.0023 high
ENSG00000057608 STAD 0.0078 low
ENSG00000057608 CHOL 0.013 low
ENSG00000057608 UVM 0.041 high
ENSG00000057608 READ 0.024 low
ENSG00000057608 KIRP 0.049 high
ENSG00000057608 THYM 0.00047 low
ENSG00000057608 BRCA 0.0014 high
ENSG00000057608 ESCA 0.0019 high
ENSG00000057608 OV 0.016 low
ENSG00000057608 PRAD 0.018 high
ENSG00000057608 TGCT 0.046 low
ENSG00000057608 BLCA 0.022 high
ENSG00000057608 LAML 0.013 low
ENSG00000057608 GBM 0.00061 low
ENSG00000057608 SKCM 0.0078 low
ENSG00000057608 CESC 0.013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000057608 LUSC Del 1.247323 0.073689 0.370142 0.419162
ENSG00000057608 LUAD Del 0.605231 0.049726 0.309838 0.234496
ENSG00000057608 LGG Amp 2.352047 0.067985 0.704937 0.128655
ENSG00000057608 BLCA Amp 11.518297 0.417692 0.709034 0.438725
ENSG00000057608 BRCA Amp 3.932541 0.198020 0.646296 0.277778
ENSG00000057608 MESO Del 1.001651 0.135642 0.511437 0.333333
ENSG00000057608 OV Amp 1.880334 0.370553 0.733878 0.449050