Ensembl ID ENSG00000056097 Gene ID 51663 Accession 17277
Gene Symbol ZFR Alias ZFR1;SPG71 Full Name zinc finger RNA binding protein
Position 5 : 32354350 - 32444740 Length 90391 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016]

ENSG00000056097 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000056097 ZFR -0.4 9.79e-24 KIRC
ENSG00000056097 ZFR 0.51 2.75e-17 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000056097 ZFR male breast cancer 10617653
ENSG00000056097 ZFR cancer 24297044
ENSG00000056097 ZFR AML 25220401
ENSG00000056097 ZFR pancreatic cancer 27177590
ENSG00000056097 ZFR pancreatic cancer 28561737
ENSG00000056097 ZFR tumor 28979805
ENSG00000056097 ZFR Gastric Cancer 29361817
ENSG00000056097 ZFR pancreatic cancer 29933757
ENSG00000056097 ZFR non-small cell lung cancer 30611568
ENSG00000056097 ZFR tumor 31010678
ENSG00000056097 ZFR non-small cell lung cancer 31407591
ENSG00000056097 ZFR breast cancer 31718519
ENSG00000056097 ZFR gastric cancer 31922886
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000056097 ZFR MESO 0.041 high
ENSG00000056097 ZFR SARC 0.00069 high
ENSG00000056097 ZFR STAD 0.028 high
ENSG00000056097 ZFR UCEC 0.038 high
ENSG00000056097 ZFR LGG 0.00014 high
ENSG00000056097 ZFR HNSC 0.017 low
ENSG00000056097 ZFR READ 0.023 low
ENSG00000056097 ZFR KIRP 0.0016 high
ENSG00000056097 ZFR KICH 0.0034 high
ENSG00000056097 ZFR BRCA 0.00099 high
ENSG00000056097 ZFR COAD 0.031 low
ENSG00000056097 ZFR ESCA 0.018 low
ENSG00000056097 ZFR OV 0.021 low
ENSG00000056097 ZFR PRAD 0.023 high
ENSG00000056097 ZFR GBM 0.033 low
ENSG00000056097 ZFR SKCM 0.00042 low
ENSG00000056097 ZFR CESC 0.037 high
ENSG00000056097 ZFR LIHC 0.00017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000056097 ZFR LUSC Amp 7.420371 0.353152 0.853892 0.750499
ENSG00000056097 ZFR LUAD Amp 4.782227 0.200029 0.699686 0.600775
ENSG00000056097 ZFR CESC Amp 0.660377 0.126448 0.967677 0.420339
ENSG00000056097 ZFR ACC Amp 1.248228 0.327339 1.271595 0.688889
ENSG00000056097 ZFR SKCM Amp 2.095513 0.164413 0.709041 0.250681
ENSG00000056097 ZFR STAD Amp 1.180229 0.146600 0.733079 0.281179