Ensembl ID
ENSG00000054267
Gene ID
51742
Accession
15550
Gene Symbol
ARID4B
Alias
BCAA;BRCAA1;RBP1L1;SAP180;RBBP1L1
Full Name
AT-rich interaction domain 4B
Position
1 : 235131634 - 235328219
Length
196586 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Canonical_RBPs
Summary
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
ENSG00000054267 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000054267
ARID4B
cancers
11481388
ENSG00000054267
ARID4B
cancers
18728284
ENSG00000054267
ARID4B
gastric cancer
21612621
ENSG00000054267
ARID4B
breast cancer
22693453
ENSG00000054267
ARID4B
breast cancer
24570593
ENSG00000054267
ARID4B
gastric cancer
24940175
ENSG00000054267
ARID4B
gastric cancer
26137913
ENSG00000054267
ARID4B
tumour
27451434
ENSG00000054267
ARID4B
gastric tumors
28045501
ENSG00000054267
ARID4B
tumors
29288040
ENSG00000054267
ARID4B
rectal cancer
29477868
ENSG00000054267
ARID4B
tumor
29797600
ENSG00000054267
ARID4B
cancer
30451916
ENSG00000054267
ARID4B
breast cancer
30675227
ENSG00000054267
ARID4B
prostate cancer
31551414
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000054267
ARID4B
STAD
0.021
high
show
ENSG00000054267
ARID4B
THCA
0.033
high
show
ENSG00000054267
ARID4B
ACC
0.00025
high
show
ENSG00000054267
ARID4B
LGG
1e-04
high
show
ENSG00000054267
ARID4B
KICH
0.011
high
show
ENSG00000054267
ARID4B
LUAD
0.016
low
show
ENSG00000054267
ARID4B
BRCA
0.012
high
show
ENSG00000054267
ARID4B
DLBC
0.038
high
show
ENSG00000054267
ARID4B
KIRC
0.0055
low
show
ENSG00000054267
ARID4B
BLCA
0.0089
low
show
ENSG00000054267
ARID4B
GBM
0.00029
low
show
ENSG00000054267
ARID4B
SKCM
0.00015
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000054267
ARID4B
SARC
Del
6.100115
0.235066
0.492984
0.338521
ENSG00000054267
ARID4B
ESCA
Amp
1.249583
0.295788
0.563883
0.489130
ENSG00000054267
ARID4B
SKCM
Amp
2.729367
0.182133
0.704471
0.528610
ENSG00000054267
ARID4B
LIHC
Amp
5.380495
0.213736
0.853594
0.716216
ENSG00000054267
ARID4B
DLBC
Del
1.262726
0.155631
0.559543
0.145833
ENSG00000054267
ARID4B
BRCA
Amp
17.766257
0.331974
0.815636
0.740741
ENSG00000054267
ARID4B
STAD
Amp
4.261293
0.222175
0.596121
0.328798
ENSG00000054267
ARID4B
PRAD
Del
2.954662
0.097703
0.540272
0.089431
ENSG00000054267
ARID4B
UCEC
Amp
3.082904
0.152415
0.862485
0.417440
ENSG00000054267
ARID4B
KIRC
Del
0.693182
0.024196
0.457452
0.079545
ENSG00000054267
ARID4B
OV
Amp
11.755300
0.576225
0.774101
0.559585
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