Ensembl ID ENSG00000048544 Gene ID 55173 Accession 14502
Gene Symbol MRPS10 Alias uS10m;MRP-S10;PNAS-122 Full Name mitochondrial ribosomal protein S10
Position 6 : 42206807 - 42217861 Length 11055 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008]

ENSG00000048544 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000048544 MRPS10 -0.5 4.91e-22 KIRC
ENSG00000048544 MRPS10 0.37 4.05e-14 BRCA
ENSG00000048544 MRPS10 0.83 1.48e-23 LUSC
ENSG00000048544 MRPS10 0.72 6.87e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000048544 MRPS10 MESO 0.047 high
ENSG00000048544 MRPS10 SARC 0.016 high
ENSG00000048544 MRPS10 PAAD 0.0037 high
ENSG00000048544 MRPS10 UCEC 0.0036 high
ENSG00000048544 MRPS10 ACC 0.018 high
ENSG00000048544 MRPS10 LUSC 0.047 low
ENSG00000048544 MRPS10 HNSC 0.0025 high
ENSG00000048544 MRPS10 KIRP 0.039 high
ENSG00000048544 MRPS10 KICH 0.0057 high
ENSG00000048544 MRPS10 LUAD 0.0049 high
ENSG00000048544 MRPS10 THYM 0.00015 high
ENSG00000048544 MRPS10 UCS 0.034 high
ENSG00000048544 MRPS10 ESCA 0.016 high
ENSG00000048544 MRPS10 OV 0.0081 low
ENSG00000048544 MRPS10 DLBC 0.031 low
ENSG00000048544 MRPS10 SKCM 0.0064 low
ENSG00000048544 MRPS10 LIHC 0.036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000048544 MRPS10 LUAD Amp 1.376004 0.135223 0.489481 0.364341
ENSG00000048544 MRPS10 COAD Amp 2.239964 0.096912 0.546402 0.219512
ENSG00000048544 MRPS10 SARC Amp 1.315971 0.295479 0.875811 0.233463
ENSG00000048544 MRPS10 ESCA Amp 5.938979 0.515019 0.901938 0.331522
ENSG00000048544 MRPS10 STAD Amp 12.697296 0.370190 0.766783 0.276644