Ensembl ID ENSG00000047849 Gene ID 4134 Accession 6862
Gene Symbol MAP4 Alias NA Full Name microtubule associated protein 4
Position 3 : 47850690 - 48089272 Length 238583 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

ENSG00000047849 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000047849 MAP4 -0.3 1.94e-15 KIRC
ENSG00000047849 MAP4 -0.8 3.30e-11 BLCA
ENSG00000047849 MAP4 -0.5 4.31e-41 BRCA
ENSG00000047849 MAP4 -0.8 3.95e-28 LUSC
ENSG00000047849 MAP4 -0.4 1.17e-11 PRAD
ENSG00000047849 MAP4 -0.5 2.15e-12 UCEC
ENSG00000047849 MAP4 -0.6 1.64e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000047849 MAP4 breast cancer 12006519
ENSG00000047849 MAP4 breast cancer 18528466
ENSG00000047849 MAP4 tumours 18657901
ENSG00000047849 MAP4 ovarian cancer 19228748
ENSG00000047849 MAP4 non-small cell lung cancer 20451371
ENSG00000047849 MAP4 bladder cancer 24140250
ENSG00000047849 MAP4 prostate tumors 26491211
ENSG00000047849 MAP4 tumor 26805736
ENSG00000047849 MAP4 tumor 26876215
ENSG00000047849 MAP4 cancer 27434957
ENSG00000047849 MAP4 Tumor 29743960
ENSG00000047849 MAP4 Ovarian Cancer 30084832
ENSG00000047849 MAP4 tumour 30737623
ENSG00000047849 MAP4 Wilms tumor 8956998
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000047849 MAP4 MESO 0.0031 high
ENSG00000047849 MAP4 SARC 0.043 high
ENSG00000047849 MAP4 CHOL 0.036 low
ENSG00000047849 MAP4 PAAD 0.02 high
ENSG00000047849 MAP4 UCEC 0.015 low
ENSG00000047849 MAP4 ACC 0.035 high
ENSG00000047849 MAP4 LUSC 0.044 high
ENSG00000047849 MAP4 READ 0.037 low
ENSG00000047849 MAP4 KIRP 0.024 low
ENSG00000047849 MAP4 KICH 0.0048 high
ENSG00000047849 MAP4 THYM 0.02 low
ENSG00000047849 MAP4 COAD 0.011 high
ENSG00000047849 MAP4 OV 0.041 high
ENSG00000047849 MAP4 BLCA 0.0012 high
ENSG00000047849 MAP4 LAML 0.029 low
ENSG00000047849 MAP4 SKCM 0.031 high
ENSG00000047849 MAP4 CESC 0.029 high
ENSG00000047849 MAP4 LIHC 0.00014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000047849 MAP4 CHOL Del 1.094305 0.240589 0.628335 0.833333
ENSG00000047849 MAP4 LUSC Del 3.638893 0.100702 0.410930 0.862275
ENSG00000047849 MAP4 LUAD Del 2.053788 0.067771 0.326787 0.478682
ENSG00000047849 MAP4 LGG Del 2.422869 0.055926 0.516868 0.095517
ENSG00000047849 MAP4 READ Del 0.710098 0.072833 0.396350 0.151515
ENSG00000047849 MAP4 COAD Del 1.160609 0.047531 0.425305 0.152993
ENSG00000047849 MAP4 UCS Del 1.579641 0.280329 0.521878 0.571429
ENSG00000047849 MAP4 THYM Del 0.970980 0.044010 0.468920 0.121951
ENSG00000047849 MAP4 SARC Del 0.864048 0.125958 0.515032 0.241245
ENSG00000047849 MAP4 PAAD Del 0.772125 0.047072 0.307315 0.271739
ENSG00000047849 MAP4 ESCA Del 0.895043 0.102969 0.434839 0.646739
ENSG00000047849 MAP4 HNSC Del 1.252488 0.060977 0.433039 0.716475
ENSG00000047849 MAP4 DLBC Del 0.941771 0.137587 0.524222 0.166667
ENSG00000047849 MAP4 BLCA Del 4.267602 0.126044 0.403808 0.279412
ENSG00000047849 MAP4 BRCA Del 24.213732 0.160894 0.454533 0.313889
ENSG00000047849 MAP4 STAD Del 5.632093 0.113666 0.348583 0.331066
ENSG00000047849 MAP4 UCEC Del 1.373073 0.056643 0.513971 0.115028
ENSG00000047849 MAP4 MESO Del 17.405056 0.551280 0.576525 0.505747
ENSG00000047849 MAP4 KIRC Del 51.122324 0.180647 0.516111 0.880682
ENSG00000047849 MAP4 OV Del 1.353239 0.189791 0.477115 0.333333