Ensembl ID ENSG00000043514 Gene ID 54802 Accession 20286
Gene Symbol TRIT1 Alias IPT;GRO1;IPPT;MOD5;hGRO1;IPTase;COXPD35 Full Name tRNA isopentenyltransferase 1
Position 1 : 39838110 - 39883511 Length 45402 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]

ENSG00000043514 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000043514 TRIT1 0.76 3.25e-22 COAD
ENSG00000043514 TRIT1 -1.0 9.35e-19 KICH
ENSG00000043514 TRIT1 1.12 1.66e-32 LUSC
ENSG00000043514 TRIT1 0.82 8.61e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000043514 TRIT1 tumor 15870694
ENSG00000043514 TRIT1 inflammatory pseudotumors 16538442
ENSG00000043514 TRIT1 lung cancer 17145094
ENSG00000043514 TRIT1 inflammatory pseudotumor 17387393
ENSG00000043514 TRIT1 tumor 18495663
ENSG00000043514 TRIT1 metastatic tumors 20148468
ENSG00000043514 TRIT1 tumor 20870208
ENSG00000043514 TRIT1 pancreatic cancer 21114864
ENSG00000043514 TRIT1 cancer 21858048
ENSG00000043514 TRIT1 tumor 21873461
ENSG00000043514 TRIT1 Tumor 22589470
ENSG00000043514 TRIT1 tumors 22649741
ENSG00000043514 TRIT1 gastric cancer 23349019
ENSG00000043514 TRIT1 tumor 24126054
ENSG00000043514 TRIT1 metastatic colorectal cancer 24865428
ENSG00000043514 TRIT1 tumors 24868227
ENSG00000043514 TRIT1 tumor 25306617
ENSG00000043514 TRIT1 inflammatory pseudotumor 26356188
ENSG00000043514 TRIT1 tumor 27119099
ENSG00000043514 TRIT1 tumour 27595400
ENSG00000043514 TRIT1 inflammatory pseudotumor 27684838
ENSG00000043514 TRIT1 lung cancer 27984194
ENSG00000043514 TRIT1 tumor 28000317
ENSG00000043514 TRIT1 prostate cancer 28693428
ENSG00000043514 TRIT1 lung cancer 28752201
ENSG00000043514 TRIT1 tumors 30079080
ENSG00000043514 TRIT1 Inflammatory pseudotumor 30755918
ENSG00000043514 TRIT1 tumors 30886794
ENSG00000043514 TRIT1 tumor 30940068
ENSG00000043514 TRIT1 cancer 30991224
ENSG00000043514 TRIT1 inflammatory pseudotumor 31220684
ENSG00000043514 TRIT1 inflammatory pseudotumors 8604685
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000043514 TRIT1 MESO 0.04 low
ENSG00000043514 TRIT1 SARC 0.024 high
ENSG00000043514 TRIT1 STAD 0.035 low
ENSG00000043514 TRIT1 CHOL 0.039 low
ENSG00000043514 TRIT1 UVM 0.04 high
ENSG00000043514 TRIT1 UCEC 0.0025 high
ENSG00000043514 TRIT1 THCA 0.0019 high
ENSG00000043514 TRIT1 ACC 0.0012 high
ENSG00000043514 TRIT1 LGG 0.0031 high
ENSG00000043514 TRIT1 KIRP 0.00049 high
ENSG00000043514 TRIT1 PCPG 0.02 low
ENSG00000043514 TRIT1 BRCA 0.035 low
ENSG00000043514 TRIT1 COAD 0.018 low
ENSG00000043514 TRIT1 UCS 0.036 high
ENSG00000043514 TRIT1 ESCA 0.009 high
ENSG00000043514 TRIT1 OV 0.0044 low
ENSG00000043514 TRIT1 KIRC 0.00026 high
ENSG00000043514 TRIT1 PRAD 0.0069 high
ENSG00000043514 TRIT1 LAML 0.01 low
ENSG00000043514 TRIT1 SKCM 0.014 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000043514 TRIT1 CHOL Del 1.945317 0.306751 0.620861 0.305556
ENSG00000043514 TRIT1 LUAD Amp 1.173447 0.129872 0.417489 0.267442
ENSG00000043514 TRIT1 KIRP Del 1.598301 0.036088 0.605328 0.142361
ENSG00000043514 TRIT1 ESCA Amp 2.333549 0.355284 0.836196 0.211957
ENSG00000043514 TRIT1 LIHC Del 3.057209 0.099487 0.507670 0.300000
ENSG00000043514 TRIT1 PCPG Del 1.385592 0.072845 0.676188 0.629630
ENSG00000043514 TRIT1 BLCA Amp 7.792226 0.347835 0.742948 0.252451
ENSG00000043514 TRIT1 UCEC Amp 1.776398 0.128349 0.571993 0.128015
ENSG00000043514 TRIT1 UVM Del 1.628635 0.094732 0.809086 0.300000
ENSG00000043514 TRIT1 OV Amp 24.766303 0.758000 0.824008 0.506045