Ensembl ID ENSG00000037757 Gene ID 84245 Accession 28469
Gene Symbol MRI1 Alias M1Pi;MRDI;MTNA;Ypr118w Full Name methylthioribose-1-phosphate isomerase 1
Position 19 : 13764522 - 13774282 Length 9761 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016]

ENSG00000037757 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000037757 0.64 3.22e-12 COAD
ENSG00000037757 0.73 4.82e-13 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000037757 tumors 19620624
ENSG00000037757 cervical cancer 20629080
ENSG00000037757 breast cancer 22888636
ENSG00000037757 breast cancer 24347097
ENSG00000037757 Breast Cancer 26947876
ENSG00000037757 tumor 28161723
ENSG00000037757 Tumor 29527574
ENSG00000037757 tumor 30039222
ENSG00000037757 tumor 30100273
ENSG00000037757 cancer 30448873
ENSG00000037757 tumours 31168263
ENSG00000037757 prostate cancer 31971614
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000037757 MESO 0.00057 low
ENSG00000037757 SARC 0.046 high
ENSG00000037757 STAD 0.006 low
ENSG00000037757 CHOL 0.042 low
ENSG00000037757 UVM 0.024 high
ENSG00000037757 UCEC 0.036 high
ENSG00000037757 ACC 0.0012 high
ENSG00000037757 LGG 0.00091 high
ENSG00000037757 LUSC 0.045 low
ENSG00000037757 READ 0.0086 low
ENSG00000037757 KICH 0.039 high
ENSG00000037757 LUAD 0.0018 low
ENSG00000037757 COAD 0.032 high
ENSG00000037757 DLBC 0.028 low
ENSG00000037757 PRAD 0.0028 high
ENSG00000037757 BLCA 0.047 low
ENSG00000037757 GBM 0.0015 low
ENSG00000037757 CESC 0.044 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000037757 THCA Del 0.931549 0.010414 0.633731 0.016032
ENSG00000037757 UCEC Amp 12.354066 0.273306 0.858899 0.187384
ENSG00000037757 OV Amp 38.724322 0.920166 1.072703 0.518135