Ensembl ID ENSG00000032219 Gene ID 5926 Accession 9885
Gene Symbol ARID4A Alias RBP1;RBBP1;RBP-1;RBBP-1 Full Name AT-rich interaction domain 4A
Position 14 : 58298504 - 58373887 Length 75384 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. [provided by RefSeq, Jul 2008]

ENSG00000032219 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000032219 ARID4A -0.6 3.63e-32 BRCA
ENSG00000032219 ARID4A -1.0 1.15e-49 LUSC
ENSG00000032219 ARID4A -0.8 3.48e-16 LIHC
ENSG00000032219 ARID4A -0.8 3.18e-17 UCEC
ENSG00000032219 ARID4A -0.6 9.35e-16 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000032219 ARID4A breast cancer 10496363
ENSG00000032219 ARID4A cancers 11481388
ENSG00000032219 ARID4A breast cancer 18211900
ENSG00000032219 ARID4A tumor 18728284
ENSG00000032219 ARID4A tumor 20441585
ENSG00000032219 ARID4A tumor 22247551
ENSG00000032219 ARID4A breast cancer 22693453
ENSG00000032219 ARID4A tumor 24379399
ENSG00000032219 ARID4A colorectal cancer 24382590
ENSG00000032219 ARID4A cancer 24570593
ENSG00000032219 ARID4A tumor 24928548
ENSG00000032219 ARID4A breast cancer 27217777
ENSG00000032219 ARID4A tumor 28486502
ENSG00000032219 ARID4A prostate cancer 29797600
ENSG00000032219 ARID4A tumour 30666492
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000032219 ARID4A MESO 0.0047 low
ENSG00000032219 ARID4A CHOL 0.013 low
ENSG00000032219 ARID4A THCA 0.043 low
ENSG00000032219 ARID4A ACC 0.023 high
ENSG00000032219 ARID4A HNSC 0.00018 low
ENSG00000032219 ARID4A PCPG 0.00013 high
ENSG00000032219 ARID4A UCS 0.027 low
ENSG00000032219 ARID4A PRAD 0.022 high
ENSG00000032219 ARID4A LAML 0.018 low
ENSG00000032219 ARID4A GBM 0.011 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000032219 ARID4A LGG Del 2.770308 0.058881 0.513650 0.198830
ENSG00000032219 ARID4A LIHC Del 0.676567 0.064666 0.495053 0.308108
ENSG00000032219 ARID4A OV Del 2.366471 0.209051 0.530931 0.502591