Ensembl ID ENSG00000024422 Gene ID 30846 Accession 3243
Gene Symbol EHD2 Alias PAST2 Full Name EH domain containing 2
Position 19 : 47713422 - 47743134 Length 29713 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]

ENSG00000024422 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000024422 2.24 3.00e-108 KIRC
ENSG00000024422 0.93 6.14e-13 HNSC
ENSG00000024422 -1.9 1.62e-114 BRCA
ENSG00000024422 -1.2 3.04e-12 COAD
ENSG00000024422 -1.4 4.88e-22 LUSC
ENSG00000024422 -1.1 5.78e-20 PRAD
ENSG00000024422 1.18 3.32e-12 KIRP
ENSG00000024422 -2.4 3.26e-42 UCEC
ENSG00000024422 -1.2 3.85e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000024422 breast cancer 25758127
ENSG00000024422 cancer 30995867
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000024422 MESO 0.0042 high
ENSG00000024422 STAD 0.0056 high
ENSG00000024422 PAAD 0.0054 high
ENSG00000024422 THCA 0.021 low
ENSG00000024422 ACC 0.05 high
ENSG00000024422 LUSC 0.029 high
ENSG00000024422 HNSC 0.0061 high
ENSG00000024422 READ 0.039 high
ENSG00000024422 KIRP 0.035 low
ENSG00000024422 LUAD 0.026 high
ENSG00000024422 PCPG 0.022 low
ENSG00000024422 COAD 0.045 high
ENSG00000024422 ESCA 0.0068 low
ENSG00000024422 OV 0.00054 high
ENSG00000024422 DLBC 0.019 low
ENSG00000024422 KIRC 0.00054 low
ENSG00000024422 BLCA 0.0049 high
ENSG00000024422 GBM 0.018 high
ENSG00000024422 SKCM 0.033 high
ENSG00000024422 CESC 0.00071 high
ENSG00000024422 LIHC 0.019 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000024422 LUSC Del 5.030134 0.113451 0.369309 0.295409
ENSG00000024422 LUAD Del 3.250723 0.079101 0.322667 0.379845
ENSG00000024422 LGG Del 14.568644 0.127681 0.664421 0.497076
ENSG00000024422 CESC Del 1.042674 0.074134 0.438431 0.122034
ENSG00000024422 UCS Del 0.904893 0.218463 0.475836 0.303571
ENSG00000024422 SARC Del 4.495728 0.208105 0.470262 0.330739
ENSG00000024422 GBM Del 10.392334 0.127779 0.525205 0.154246
ENSG00000024422 PAAD Del 0.892302 0.049425 0.309122 0.125000
ENSG00000024422 TGCT Del 1.181351 0.069290 0.343644 0.386667
ENSG00000024422 UCEC Del 1.483343 0.057848 0.465310 0.115028
ENSG00000024422 OV Del 15.193174 0.345363 0.582112 0.516408