Ensembl ID ENSG00000011007 Gene ID 6924 Accession 11620
Gene Symbol ELOA Alias SIII;ELOA1;TCEB3;TCEB3A;SIIIp110 Full Name elongin A
Position 1 : 23743448 - 23762059 Length 18612 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008]

ENSG00000011007 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000011007 -0.2 3.70e-14 KIRC
ENSG00000011007 -0.5 2.09e-15 KIRP
ENSG00000011007 -0.5 5.06e-12 LIHC
ENSG00000011007 -1.4 2.49e-15 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000011007 tumor 10224134
ENSG00000011007 tumor 10760578
ENSG00000011007 tumour 19594832
ENSG00000011007 tumor 20977665
ENSG00000011007 tumor 24260444
ENSG00000011007 tumor 8810329
ENSG00000011007 tumor 8896449
ENSG00000011007 tumor 9869640
ENSG00000011007 tumour 9931330
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000011007 MESO 0.0059 high
ENSG00000011007 SARC 0.0023 high
ENSG00000011007 CHOL 0.029 high
ENSG00000011007 UVM 0.013 high
ENSG00000011007 PAAD 0.044 low
ENSG00000011007 THCA 0.02 high
ENSG00000011007 ACC 0.0033 high
ENSG00000011007 LUSC 0.035 high
ENSG00000011007 HNSC 0.032 high
ENSG00000011007 READ 0.0051 high
ENSG00000011007 KIRP 0.0012 high
ENSG00000011007 KICH 0.0015 high
ENSG00000011007 LUAD 0.016 low
ENSG00000011007 PCPG 0.011 low
ENSG00000011007 COAD 0.022 low
ENSG00000011007 ESCA 0.028 low
ENSG00000011007 OV 0.026 high
ENSG00000011007 DLBC 0.043 low
ENSG00000011007 KIRC 0.001 low
ENSG00000011007 PRAD 0.0087 low
ENSG00000011007 TGCT 0.042 high
ENSG00000011007 SKCM 0.0041 high
ENSG00000011007 CESC 0.0032 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000011007 CHOL Del 20.867648 1.058591 0.678521 0.805556
ENSG00000011007 LUSC Del 4.868353 0.111939 0.385920 0.449102
ENSG00000011007 LUAD Del 1.302126 0.059588 0.293604 0.244186
ENSG00000011007 CESC Del 1.698518 0.086245 0.447045 0.115254
ENSG00000011007 KIRP Del 6.500312 0.076312 0.594947 0.177083
ENSG00000011007 READ Del 8.401119 0.206032 0.447014 0.448485
ENSG00000011007 COAD Del 19.132784 0.163958 0.453997 0.363636
ENSG00000011007 GBM Del 8.374892 0.115207 0.571531 0.109185
ENSG00000011007 PAAD Del 2.386413 0.077080 0.347250 0.326087
ENSG00000011007 ESCA Del 0.886991 0.102381 0.343360 0.358696
ENSG00000011007 SKCM Del 2.339114 0.091155 0.452819 0.198910
ENSG00000011007 HNSC Del 2.676189 0.074458 0.365855 0.181992
ENSG00000011007 LIHC Del 15.215439 0.203655 0.540757 0.372973
ENSG00000011007 PCPG Del 1.991460 0.084874 0.674895 0.623457
ENSG00000011007 BLCA Del 0.662691 0.075626 0.314154 0.188725
ENSG00000011007 BRCA Del 32.808637 0.184351 0.424941 0.408333
ENSG00000011007 STAD Del 4.574800 0.104828 0.353949 0.263039
ENSG00000011007 UCEC Del 10.018316 0.120317 0.500016 0.139147
ENSG00000011007 MESO Del 3.592314 0.227730 0.527430 0.321839
ENSG00000011007 KIRC Del 6.993638 0.054953 0.419977 0.181818
ENSG00000011007 UVM Del 2.306078 0.116385 0.819526 0.312500
ENSG00000011007 OV Del 25.024291 0.417166 0.547605 0.430052